Blood types/ transfusions Flashcards
(9 cards)
what is the universal donor group
O - has anti-a and anti-b antibodies
what is the universal recipient blood group
ab - no antibodies
what are the natural antibodies (blood groups)
anti-a/ anti-b = anti-erythrocyte antibodies
what is the optimum temperature of anti-erythrocyte antibodies
4 degrees - ‘cold’ antibodies’
what is the optimum temperature of immune antibodies
37 degrees - warm
what immunoglobulin can/ can’t cross placenta
IgM don’t, IgG can
what does rhesus positive mean
D antigen present
what is prevalence of rhesus negative
15%
what happens in haemolytic disease of the foetus and newborn (HDFN)
rhesus negative mother had rhesus positive baby; 1st baby is fine but mother sensitised to rhesus positive blood - makes IgG anti-D; crosses placenta and haemolyses foetuses RBCs