BMF Flashcards
(8 cards)
1
Q
what does aplastic anaemia present with?
A
pancytopenia
- anaemia
- infection
- bleeding
2
Q
what are three inherited causes of aplastic anaemia ?
A
fanconis anaemia
dyskeratosis congenita
swachman diamond syndrome
3
Q
what is fanconis anaemia ?
A
aplastic anaemia
4
Q
state some causes of pancytopenia ?
A
aplastic anaemia BM infiltration leukaemia lymphoma myelofibrosis myelodysplasia megaloblastic anaemia HIV
5
Q
state some drugs that cause pancytopenia?
A
methotrexate thaizides carbimazole - antithyroid clozapine phenytoin
6
Q
what are the three signs of pancytopenia?
A
anaemia
infection
bleeding
7
Q
what does the bone marrow look like in aplastic anaemia?
A
hypo cellular marrow
8
Q
what is the treatment for aplastic anaemia?
A
transfusion
allogenic BMT
anti thymocyte globulin
