BMS 108 Ch. 20 Reproductive System Flashcards
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How many chromosomes does each gamete have? What is a cell with 46 chromosomes called? 23?
23; diploid; haploid
What is a gamete?
a sex cell formed in the gonads by meiosis
What is a zygote?
a 46 chromosome cell resulting from fusion of sperm and egg during fertilization
Each zygote inherits 23 chromosomes from mother and 23 from father. Producing 23 pairs of ___________ chromosomes. 22 of these are ___________ chromosomes and the 23rd pair are __________ chromosomes.
homologous; autosomal; sex
What are the sex chromosomes of a female? male?
XX; XY
How is chromosomal gender of the zygote determined?
All ova contain X chromosomes, some sperm contain X chromosomes and others contain Y chromosomes. Which type of sperm fertilizes the egg determines the sex of the zygote.
What chromosome induces the formation of testes?
Y chromosome
What induces the formation of male sex organs?
testosterone from the testes
Gametes are produced by what process?
Meiosis
There are two phases of meiosis, meiosis I and meiosis II. Where does the reduction in genetic material occur?
meiosis I
What are the four phases of meiosis I? Meiosis II?
Prophase, metaphase, anaphase, telephase; same as meiosis I
Describe the general interactions between the hypothalamus, anterior pituitary and gonads in the production of gametes.
- Hypothalamus releases GnRH to anterior pituitary
- Anterior pituitary releases LH and FSH which stimulates the production of sperm and eggs and gonadal sex steroids; also maintains the size of gonads
- sex steroids provide negative feedback to the hypothalamus and anterior pituitary
- gonads also secrete the hormone inhibin, which negatively feeds back on FSH secretion
What causes puberty?
- FSH and LH secretion is high for first 6 mos. of life, but fall to very low levels until puberty
- At puberty hypothalamus increases GnRH secretion»_space;> increases FSH and LH secretion
- Stimulates sex steroid secretion»_space;> drives changes in secondary sex characteristics and menarche (first menstrual flow)
What determines age of puberty in girls?
% body fat and activity level. Girls with low body fat and high activity levels enter puberty at an older age
What is an ovarian follicle?
an oocyte + surrounding follicle cells
What do follicle cells secrete?
estrogen
Describe the production of oocytes.
- At 5 month gestation, ovaries contain 6-7 million oogonia
- Toward the end of gestation, oogonia become primary ooctyes and begin meiosis I, but arrest in prophase (2n)
- There is continual loss of primary oocytes throughout life (2 million left at birth, 400,000 left at puberty)
- 400 oocytes are ovulated during reproductive years, the rest undergo apoptosis (programmed cell death)
Describe the process of follicular development.
- Primary follicle contains a primary ooctye & a layer of follicle cells
- In response to FSH, some follicles enter the ovarian cycle and grow
- Some primary follicles continue to develop and become secondary follicles (same as primary follicle but has more follicle cells and antrum)
- Graafian (mature) follicle contains a secondary ooctye (n) and is ready for ovulation
What is the menstrual cycle?
a month long cycle of ovarian activity characterized by shedding of endometrial lining of the uterus and bleeding (menstruation)
What is the follicular phase?
- Lasts from day 1 to about 13
- Dominated by growth of primary follicles into secondary follicles & production of estradiol
- One survivor becomes a graafian follicle, reaching peak at about day 12
What is follicular growth and estrogen secretion dependent on?
FSH from the Anterior Pituitary
What kind of receptors does FSH and estrogen recruit in graafian follicles?
LH
Describe how the events in the follicular phase cause ovulation.
- Rapidly rising estrogen secretion causes the hypothalamus to increase pulses of GnRH, resulting in greater LH secretion
- A positive feedback between estrogen and anterior pituitary develops, resulting in a LH surge that causes ovulation
What is the phase that follows the follicular phase?
the luteal phase