BMS11004 - WEEK 6 TUESDAY Flashcards
what is orexigenic brain area
appetite promoting area, lateral hypothalamus
what is orexin
neuropeptin which stimulate appetite
what is anorexigenic brain area
suppress hunger, ventromedial nucleus
what is leptin
hormone produced by fat, and reduce fat
lacking leptin - obese
high body fat- more leptin
how does leptin reduc body fat
inhibit parasympathetic nervous system, activate sympathetic
increased blood glucose inhibits lateral hypothalamus, promote insulin producing, inhibit hunger promoting neuron (orexigenic), activate anorexigenic
how does GLP-1 agonists (semaglutide) work to lose weight
mimic action of GLP-1, promote insulin produce
summary for homeostasis
maintained by negative feedback loops, must be odd number of inhibitive arrows in loop
can be investigated by add/remove key peptide or hormone, inhibit brain area
what does lesioning amygdala cause
show less fears
what kind of aggression does medial hypothalamus cause
affective aggression
elec stim in cats shows anger, rage
what kind of aggression does lateral hypothalamus cause
predatory aggression
elec stim in cats causes primal behaviour, stalking rats to eat
what do rats with destroyed mesolimbic dopaminergic projections behave
enjoys food but lacks motivation to get it, dopamine drives motivation than enjoyment
whats somatic marker hypothesis in dopamine reward
embodied decision-making, emotions as gut feelings
orbitofrontal lesion don’t show anticipation strese
whats common sense theory of emotions
sensory input - emotional experience - physiological reaction
whats James-Lange theory of emotion
sensory input - physiological reaction - emotional experience
whats Cannon-Bard theory of emotion
sensory input - emotional experience, physiological reaction at same time
