Board Vitals Questions Flashcards
(633 cards)
What meds are FDA approved to treat bipolar depression?
Seroquel
Latuda
Zyprexa + Prozac
What are Standard Deviations?
68-95-99.7
Sleep Stages
Stage 1 - 5%
State 2 - 50% (sleep spindles and K-complexes on EEG)
Stage 3 - 10-20% (deep/delta)
REM - 20-25% (dreams)
Non-REM/REM alternate every 90-100 - REM periods become increasingly longer as the night progresses
TCAs and seizures
- lower sz threshold
- levels may inc w/sz meds
metabolic monitoring for antipsychotics
fasting blood glc - baseline, 12wk, annual
BP - baseline, 12wk, annual
BMI - baseline, 4wk, 8wk, 12wk, quarterly
waist circum - baseline, annual
fasting lipid - baseline, 12wk, 5yr
ECT modalities
bilateral unilateral non dominant (right) - fewer cognitive SEs, less sx reduction (no absolute contraindications) 6-10 sessions 3x/wk 1 sz/session 25 second sz
can switch from uni to bilateral after 4-6 treatments if no improvements
Williams syndrome
ADHD elfin facies starburst facies IDD cheerful demeanor ease with strangers heart & blood vessel problems strabismus hypermuscularity hyperacusis (sensitivity to sounds)
autism spectrum disorder
1%
communication
social interaction
restriction of activities
childhood onset fluency disorder
5%
vagus nerve stimulation
FDA approvals
- epilepsy
- treatment resistant depression
placed in carotid sheath
thoracic/abdominal viscera - medulla
4 failed trials
ADHD
9%
2: 1 male:female (kids)
1. 6:1 male:female (adults)
adult cut off 5 sx (of 18)
kid cut off 6 sx
6mths
prior to age 12
ADHD + tics
clonidine
guanfacine
stimulant max doses (kids)
dexmethylphenidate (Focalin) 20mg
Methylin, Ritalin, Metadate 60mg
methylphenidate-OROS (Concerta) 72mg
methylphenidate patch (Daytrana) 30mg
meds to avoid w/ECT
theophylline - prolongs szs
hypoglycemincs (insulin/orals)
beta blockers - asystole
lidocaine - reduce sz induction
lithium - prolong sz and confusion/postictal delirium
clozapine (late appearing sx)
bupropion (late appearing sx)
benzos (anticonvulsant)
basilar migraine
transient headache occipital pain aura quadriplegia (stroke like) stupor psychosis blindness coma
serotonin syndrome
clonus
tachycardia
hyperthermia
leukocytosis rhabdomyolysis abnormal LFTs hypocalcemia hyponatremia hypomagnesemia
myoglobin - test for rhabdo
cocaine inhibits reuptake of serotonin
amphetamines dextromethorphan MDMA (ecstasy) St. Johns wort nefazodone meperidine (Demerol) fentanyl antiemetics carbamazepine antimigraine meds l-tryptophan
Korsakoff’s syndrome
thiamine deficiency
anterograde and retrograde amnesia
confabulation
apathy
herpes simplex encephalitis
temporal lobe
inferomedial frontal lobe
personality/behavior change
psychosis
gustatory & olfactory hallucinations
anosmia
xanthochromia PLEDS (periodic lateralized epileptiform discharges) on EEG
IV acyclovir
anterior pituitary
FSH LH ACTH TSH Prolactin Endorphins GH
brain cell types
neurons
glia
- astrocytes
- microglia (act like macrophages)
- macroglia
- -oligodendrocytes (insulate axons in CNS w/myelin sheath)
- -astrocytes (BBB, repair/scarring)
- -ependymal cells (line ventricles and help produce CSF)
- -radial glia (primary progenitors - neurons, astrocytes, oligos)
- -Schwann cells (myelinated nerves in PNS)
adrenoleukodystrophy
x-linked
accum. very long-chain fatty acids (VLCFA)
- myelin of CNS and adrenal cortex
mutations in ABCD1
vision & hearing impairment aphasia hyperactivity paralysis seizures muscle weakness adrenal failure coma
left parietal lobe
dominate
Gerstmanns syndrome
right-left confusion agraphia acalculia aphasia agnosia (inability to interpret sensations)
right parietal lobe
non dominate
dressing apraxia
difficulty understanding how things relate in space
left hemineglect
Brocas area
left frontal lobe
expressive aphasia
- understand what is being said
- difficulty forming spoken words
impaired naming and repetition
production of speech