body parts Flashcards

(49 cards)

1
Q

What are the main functions of the kidney?

A

Removal of waste and maintenance of fluid and electrolyte balance.

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2
Q

What fluid does the kidney help regulate?

A

Extracellular fluid, especially blood.

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3
Q

What concept does kidney support to avoid accumulation?

A

Mass balance – everything entering the body must eventually leave.

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4
Q

What is the functional unit of the kidney?

A

The nephron.

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5
Q

What does the nephron do?

A

Makes urine and balances blood composition through filtration and reabsorption.

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6
Q

What are the three main tubes connected to the kidney?

A

Renal artery, renal vein, and ureter.

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7
Q

What are the two layers of the kidney?

A

Renal cortex (outer) and renal medulla (inner).

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8
Q

What structure funnels urine into the ureter?

A

Renal pelvis.

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9
Q

Where does filtration occur in the nephron?

A

Renal corpuscle, made up of the glomerulus and Bowman’s capsule.

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10
Q

What is the glomerulus?

A

A porous capillary network where filtration begins.

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11
Q

What is ultrafiltration?

A

Water pressure forcing material out of the glomerulus into the Bowman’s capsule.

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12
Q

What increases pressure in the glomerulus?

A

Narrower exit vessel compared to entry vessel.

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13
Q

What are the layers material passes through during filtration?

A

Capillary wall, glomerular basement membrane, podocyte foot processes.

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14
Q

What does inulin test?

A

Kidney filtration, as it is not reabsorbed.

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15
Q

What is the role of microvilli in the proximal convoluted tubule?

A

Increases surface area for absorption.

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16
Q

How is glucose reabsorbed?

A

By active transport with sodium via cotransporters in the proximal tubule.

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17
Q

What is the loop of Henle’s function?

A

Concentrates urine by removing water and pumping out solutes.

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18
Q

Why does water move out of the descending limb?

A

Because of increasing solute concentration in the surrounding fluid.

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19
Q

What happens in the ascending limb of the loop of Henle?

A

Solutes (like sodium and chloride) are actively pumped out, but water is retained.

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20
Q

What hormone increases water reabsorption in the collecting duct?

A

ADH (antidiuretic hormone).

21
Q

How does ADH work?

A

It inserts aquaporins into the collecting duct walls, increasing water reabsorption.

22
Q

What triggers ADH release?

A

High solute concentration in the bloodstream, detected by the hypothalamus.

23
Q

What hormone regulates potassium excretion?

24
Q

How does aldosterone affect potassium and sodium?

A

It increases sodium reabsorption and potassium secretion using sodium-potassium ATPases.

25
What part of the nephron prevents red blood cells from entering urine?
The glomerular filter.
26
What does 'hepatic' mean?
Pertaining to the liver.
27
What does the liver produce to help clot wounds?
Coagulation factors.
28
What is the liver’s role in hormone regulation?
It inactivates hormones to regulate their concentration.
29
How does the liver protect against infection?
It destroys bacteria and viruses from the gut before they enter the bloodstream.
30
What is the hepatic portal vein?
A vessel that brings nutrient-rich, low-oxygen blood from the gut to the liver (75% of blood supply).
31
What is the hepatic vein?
Carries blood away from the liver after filtration and nutrient processing.
32
What is the hepatic artery?
Supplies oxygen-rich blood to the liver from the heart (25% of blood supply).
33
What are liver lobules?
Hexagonal functional units of liver tissue with a central vein and portal triads at the corners.
34
What are hepatocytes?
Liver cells (80% of liver cells) that filter blood and produce bile.
35
What is the portal triad?
Consists of a hepatic artery branch, portal vein branch, and hepatic duct.
36
Where is bile made and where does it go?
Made by hepatocytes in lobules; flows to the hepatic duct and into the digestive system.
37
How does the liver maintain glucose homeostasis?
Through glucagon (releases glucose) and insulin (stores glucose).
38
How does the liver help regulate cholesterol?
By distributing cholesterol using lipoproteins: LDL and HDL.
39
What is LDL?
Low-density lipoprotein; transports cholesterol from the liver to body cells and vessels (bad cholesterol).
40
What is HDL?
High-density lipoprotein; collects cholesterol from body and returns it to the liver (good cholesterol).
41
What is albumin?
A plasma protein made by the liver that maintains osmotic balance in blood vessels.
42
What causes swelling in tissues?
Water moves out of capillaries via osmosis due to lower osmolarity in the blood.
43
Why is iron important?
It helps transport oxygen in red blood cells by being part of hemoglobin.
44
What is transferrin?
A protein that carries two atoms of iron in the blood.
45
What is ferritin?
A protein complex that stores iron in the liver.
46
How is iron recycled?
From old red blood cells broken down by white blood cells.
47
What is hepcidin?
A hormone made by the liver that regulates iron levels by degrading ferroportin channels.
48
What does high hepcidin do?
Prevents iron from entering the bloodstream by degrading ferroportin.
49
What is ferroportin?
A channel protein that allows iron to pass through the cell membrane into the bloodstream.