bone tumors

Question 0

permeated lesions

Answer 0

motheaten; confluent little holes

fast growing things

Question 1

sclerotic/geographic margin

Answer 1

slow growing lesion so that bone has time to respond to it

–bone thickened around sharp margin

Question 2

lesion mineralization suggests

Answer 2

it contains calcium

Question 3

with calcium, a dense lesion in the bone shaft may be

Answer 3

hard to catch

Question 4

stipped, flocculent and rings and arches patterns suggest

Answer 4

cartilage is mineralizing

Question 5

periosteium reflects

Answer 5

triggers inside and outside the bone that determine speed of growth

Question 6

slow growing cortical lesion

Answer 6

continuous pattern of periosteum around it- forming bump

Question 7

onion skin pattern in periosteum reflects

Answer 7

waxing and waning of growth speed

Question 8

interrupted pattern reflects

Answer 8

fast growth

Question 9

flocculent

Answer 9

calcified cartilage where it shouldnt be

Question 10

slow growth rate

Answer 10

georgraphic margin

solid periosteal rxn

Question 11

intermediate growth rate

Answer 11

ill defined internal margin/moth eaten

shells periosteal rxn

Question 12

fast growth rate

Answer 12

permeative internal margin

lamellar periosteal rxn

Question 13

Fastest growth rate

Answer 13

invisible internal margin

periosteal rxn spiculated invisible

Question 14

geographic lesions include

Answer 14

cysts
chondroma
fibrous dysplasia
giant cell tumor
chrondrosarcoma
osteomyelitis
metastasis

Question 15

moth eaten tumors include

Answer 15

osteosarcoma
ewing sarcoma
chondrosarcoma
osteomyelitis
metastasis

Question 16

permeative tumors include

Answer 16

osteosarcoma
ewing sarcoma
chondrosarcoma
osteomyelitis
metastatsis

Question 17

tumors of the diaphysis

Answer 17

ewing sarcoma (middle)
osteoid osteoma (edge)
fibrous dysplasia (middle small)
chondromyloid fibroma( edge with metaphysis)

Question 18

tumors of metaphysis

Answer 18

cysts (middle)
osteochondroma (sticking off side)
osteosa (large middle) 
non-ossifying fibroma (side)
cartilage neoplasms (middle)
giant cell tumor (edge + epiphysis)

Question 19

epiphysis tumors

Answer 19

chrondroblastoma

Question 20

what tumor is not seem in kids

Answer 20

chondrosarcoma

Question 21

what tumor is not seen in metaphysis

Answer 21

ewing

Question 22

what suggests osteomyelitis

Answer 22

increase WBC with a swollen finger

Question 23

primary bone lesions are usually

Answer 23

signular

Question 24

bone forming tuors (2)

Answer 24

osteoid osteoma | osteosarcoma

Question 25

cartilage forming tumors (3)

Answer 25

osteochrondroma chonrome chrondosarcoma

Question 26

round cell maliginancies

Answer 26

ewing's tumor lymphoma multiple myeloma

Question 27

fibrous tumor like conditiosn

Answer 27

fibrous dysplasia

Question 28

fibrous dysplasia

Answer 28

diaphyseal, intramedullary fusiform lesiosn with a ground glass appearance that can be associated with growth deformities

Question 29

histo of fibrous tumor-like conditions

Answer 29

spindle cells in a colalgenous matrix with woven bone

Question 30

clinical releavance of fibrous dysplasia

Answer 30

greater in female | usually in children

Question 31

ewing's sarcoma

Answer 31

childhood malig of primitive mononuclear cells, often presents a diagnostic challenge since its pathological presnetation can mimic ALL and metastatic neuroblastoma

Question 32

where in bone is ewing's

Answer 32

meta-diaphyseal permative lesion with prominent periosteal rx

Question 33

clinical path of swing's

Answer 33

age range 5-15 years presentation with pain mets to other bones and lung

Question 34

molecular cytogenetics of ewings

Answer 34

translocation of chrom 11;22 -->results in fusion protein EWS FLI-1

Question 35

osteosarcoma path

Answer 35

metaphyseal, most often about the knee (most active bone growth) radio appearance depends on histo (osteoblastic vs chondroblastic) and location (intramedullary, cortical, periosteal)

Question 36

clinical age for osteosarcoam

Answer 36

10-25 years, more in men

Question 37

clinical presentation osteosarcoma

Answer 37

pain--persistant and sometimes welling or pathologic freacture mets blood and pulm

Question 38

giant cell tumor is

Answer 38

benign but aggressive

Question 39

giant cell tumor path

Answer 39

metaphyseal lytic lesion ususally appearing after closure of the growth plates and therefore can extend epiphyseally; usually above the knee

Question 40

clinical course of giant cell tumor

Answer 40

ages 20-40 years | may present with pain, pathologic fracture, and recurrence rate is high if primary surgical treatment is inadequate

Question 41

chrondosarcoma is

Answer 41

malginant

Question 42

chrondosarcoma can be both

Answer 42

intramedullary or peripheral

Question 43

clinical path of chrondrosarcoma

Answer 43

adults, usually >50 slwolwy enlarging sometimes painful--can become quite large, particularly when they arise in pelvic bones

Question 44

osteomyelitis

Answer 44

sweollen and painful arm

Question 45

staph osteomylitis shows

Answer 45

empty trabeculae (dead osteoblasts)

Question 46

tx of osteomyelitis

Answer 46

w/ IV abx

Question 47

benign endochondroma

Answer 47

varaibale radiographic appearance depdenent on size, location of bone, degree of calc lytic with speckled calcification- usually solitary although multiple forms are seen and represent rare clinical syndromes

Question 48

Ollier's

Answer 48

>1 chrondroma with fibrous displasia (in ref to endochondromas)

Question 49

Maffuci's

Answer 49

>1 chondroma with angiomata (in ref to endochondroma)

Question 50

clinical present wtih benign endochondroma

Answer 50

variable presentations --most common being that of an incidental radiographic finding

Question 51

osteoid osteoma is

Answer 51

benign

Question 52

osteoid osteoma path

Answer 52

diaphyseal | usually cortical in location with sclertoci thickening within which a small lucent nidus is found

Question 53

nidus is composed of

Answer 53

rich vascularized disorganized woven bone and osteoid

Question 54

clinical presenation of osteoid osteoma

Answer 54

adolescents (3:1 male:F) 50% femur pain, progressive severity, often at night

Question 55

how is osteoid osteoma relieved

Answer 55

with aspirin