Bone Tumours Flashcards

(41 cards)

1
Q

Where do osteosarcomas commonly metastasise?

A

Lung (blood-borne)

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2
Q

What are the radiological features of osteosarcoma?

A

Mixed Lytic + sclerotic zones in the metaphysics.

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3
Q

What is the common management of osteosarcoma?

A

Surgical resection+/- chemo for lung mets

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4
Q

Which area of bone do osteosarcomas affect?

A

Metaphyseal ends of long bones (distal femur + proximal tibia most common)

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5
Q

Which population does chondrosarcoma usually affect?

A

Middle aged + Elderly

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6
Q

Which area of bone do chrondrosarcomas affect?

A

Medulla or Juxtacortical

Pelvis, ribs, proximal humerus or proximal femur

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7
Q

Are chondrosarcomas fast or slow growing?

A

Slow growing, seldom metastasise

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8
Q

What are the x-ray features of chondrosarcomas?

A

Prominent end-steal scalloping and cortical thickening

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9
Q

Are radiotherapy/chemotherapy effective in chondrosarcoma?

A

No

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10
Q

Which population does ewing sarcoma affect?

A

Children

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11
Q

Which area of bone does ewing sarcoma affect?

A

Diaphysis of long bones (femur + flat bones of pelvis)

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12
Q

What are the radiological features of ewing sarcoma?

A

Lytic lesions with periosteal reactions

‘Onion’ skin appearance

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13
Q

How are ewings sarcomas managed?

A

Resection + neoadjuvant chemo

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14
Q

What is the characteristic clinical feature of osteoid osteomas?

A

Pain at night relieved by NSAIDs

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15
Q

What are the radiological features of osteoid osteomal??

A

Lucent area surrounded by reactive sclerosis.

usually <2cm

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16
Q

Which area of bone does osteoid osteoma affect?

A

shaft of long bones

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17
Q

Who does osteoid osteoma affect?

A

Males, 10-25yrs

18
Q

Who does osteochondroma affect?

A

Males, 2nd decade

19
Q

What are the clinical features of osteochondroma?

A

Asymptomatic, slow growing

20
Q

What are the radiological features of osteochondroma?

A

Pedunculated bony outgrowth from metaphysics

21
Q

How are osteoid osteomas typically managed?

A

Conservatively

22
Q

How are osteochondromas typically managed?

A

Conservatively

23
Q

Who are affected by chondromas?

24
Q

Which part of the bone is affected by chondroma?

A

Metaphysis of long bones of hands, feet, humerus, femur, tibia

25
How do chondromas usually present?
Incidental
26
What are the radiological features of chondroma?
Elongated, oval, lytic areas
27
How are chondromas managed?
Asymptomatic - conservative | Symptomatic - surgical
28
Which diseases are chondromas associated with?
Olliers disease | Maffuci syndrome
29
What are the features of giant cell tumours (osteoclastomas)?
Pain | Benign but locally aggressive
30
What are the radiological features of giant cell tumours?
'Soap bubble' appearance | Eccentric lytic areas
31
How are giant cell tumours managed?
Surgical resection | small risk transformation to osteosarcoma
32
Which part of bone do giant cell tumours present?
Epiphysis of long bones | 50% around knee
33
Who is affected by giant cell tumours?
20-40 years
34
How do bone cysts usually present?
Adolescent boys | Asymptomatic or pathological Fracture
35
What are the radiological features of bone cysts?
Ovoid radiolucent area
36
What staging system is used for primary bone tumours?
Enneking staging
37
What are the most common primary site of bone metastasis?
``` Renal Thyroid Prostate Lung Breast ```
38
What scoring system is used to stratify fracture risk in metastatic bone lesions?
Mirel scoring system
39
what is the most common soft tissue sarcoma of childhood?
Rhabdomyosarcoma
40
Pagets disease causes what x-ray findings
Cortical thickening
41
which cell type is implicated in osteopetrosis?
osteoclasts