Bone Tumours Flashcards

(38 cards)

1
Q

What is the most common bone tumour?

A

Bone metastasis

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2
Q

Which tumours commonly metastasise to bone?

A
Renal 
Thyroid 
Lung 
Prostate
Breast
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3
Q

What are the features of bone tumours?

A

Pain

  • not associated with movement
  • worse at night
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4
Q

What are common benign bone tumours?

A
Osteoid osteoma 
Aneurysmal bone cyst 
Chrondroblastma 
Osteochondroma
Chrondroma 
Giant cell tumour
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5
Q

What cell type does an osteoid osteoma arise from?

A

Osteoblast

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6
Q

What are risk factors for osteoid osteomas?

A

Male

10-20 yrs

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7
Q

What part of the bone do osteoid osteomas affect?

A

Diaphysis of long bones

Spine

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8
Q

What are the features of osteoid osteomas?

A

Localised pain

  • worse at night
  • relieved by NSAIDs
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9
Q

What is seen on an x-ray with osteoid osteomas?

A

Sclerosis with lucent nidus

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10
Q

What is an aneurysmal bone cyst?

A

Blood filled cyst growing in bone

‘Blown out appearance’- x-ray

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11
Q

What age do aneurysmal bone cysts affect?

A

Birth - 20 years

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12
Q

How are aneurysmal bone cysts managed?

A

Embolisation

Radiotherapy

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13
Q

What are chondroblastomas?

A

Rare benign cartilaginous tumours that arise in the epiphyseal region

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14
Q

What age do chondroblastomas affect?

A

<25 years

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15
Q

How are chondroblastomas managed?

A

Curettage + bone graft

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16
Q

What are osteochondromas?

A

Outgrowth from metaphysis of long bones covered with a cartilaginous cap

17
Q

What are risk factors for osteochondromas?

A

Male

10-20 years

18
Q

What is seen on an x-ray with an osteochondroma?

A

Pedunculated bony outgrowth

19
Q

What cells do chondromas arise from?

A

Chondroblasts

20
Q

What bones do chondroblasts typically affect?

A

Long bones

  • hands
  • femur
  • humerus
21
Q

What is seen on an x-ray with an chondroma?

A

Well circumscribe oval lucency with intact cortex

22
Q

What are giant cell tumours also known as?

A

Osteoclastomas

23
Q

What cells do giant cell tumours arise from?

A

Multinucleated giant cells

Stromal cells

24
Q

What part of the bone do giant cell tumours affect?

25
What is seen on x-rays with giant cell tumours?
Eccentric lytic area = 'soap bubble' appearance
26
How are giant cell tumours managed?
Surgical resection
27
What are common malignant bone tumours?
Osteosarcoma Ewing's sarcoma Chondrosarcoma
28
What is an osteosarcoma?
Most common malignant primary bone tumour
29
What part of the bone do osteosarcomas affect?
Metaphysis of long bones
30
What is seen on an x-ray with an osteosarcoma?
Lytic sclerosis Codman's triangle Sunray spiracles
31
How are osteosarcomas managed?
Chemotherapy En-bloc resection Amputation
32
What is Ewing's sarcoma?
Paediatric malignancy arising from poorly differentiated neuroectodermal cells
33
What part of the bone does Ewing's sarcoma affect?
Diaphysis
34
What is seen on an x-ray with Ewing's sarcoma?
Onion skin appearance
35
How is Ewing's sarcoma managed?
Chemotherapy En-bloc resection Amputation
36
What is chondrosarcoma?
Malignant tumour of the cartilage
37
What is seen on an x-ray with chondrosarcoma?
Popcorn sign
38
How is chondrosarcoma managed?
Surgical resection