Bovine 1 Flashcards
(85 cards)
Malignant Catarrhal Fever:
- causative agent?
Ovine herpesvirus 2
Malignant Catarrhal Fever:
- pathophys of disease
affects lymphocytes & allows animals own killer cells to attack BV’s leading to arteritis and multisystemic signs
Malignant Catarrhal Fever:
- KEY C/S?
- high fever, enlarged LNs
Malignant Catarrhal Fever:
- other multisystemic signs
- diarrhea
- oral erosions
- mucopurulent nasal discharge
- peeling nose
- corneal opacity
- ocular discharge
- CNS signs
- lameness
- sloughing of hooves
Malignant Catarrhal Fever:
- Dx?
- ELISA serum antibodies
- PCR (false negs)
Malignant Catarrhal Fever:
- prevention
- keep cattle and sheep seperate
- no vx avail
BVDV:
- Etx agent?
Pestivirus
BVDV:
- describe the different ways the disease presents and the clinical signs associated
1.) Subclinical
2.) Acute
- 6-24m of age
- fever, leukopenia, oculonasal discharge, oral erosions/ulcers, diarrhea
- immunosuppressed, pneumonia
3.) Hemorrhagic Syndrome:
- thrombocytopenia
4.) Reproductive loss:
- infertility & EED @ any stage of gestation
- congenital defects when infected 100-150d
- PI fetal infxn when infected 40-120d
5.) Mucosal/Chronic BVD:
- PI animal is superinfected w/ CP or NCP switches to CP
- peracute, often fatal
BVDV:
- Diagnosis
antigen detection
- fluorescent antibody
- IHC (ear notch)
- ELISA
BVDV:
- How does it affect reproduction
- infertility and EED at any stage of gestation
- PI infections 40-120d
- congenital defects 100-150d
IBR:
- Etx?
Bovine Herpes virus 1
IBR:
- Tranmission?
- airborne or direct contact
- in utero, at breeding or at birth
IBR:
- C/S?
1.) Respiratory
- fever, red nose +/- white plaques, non-productive cough, decreased appetite
- usually entire herd
2.) Abortion
- 5-6m gestation
- can induce abortion w/ live vx
3.) Ocular:
- severe conjunctivitis, clear xs ocular discharge w/ corneal opacity
4.) Infectious Pustular Vulvuovaginitis
- red spots & pustules lining vulva and vagina
- xs tail swtiching, frequent urination, decreased milk prod’n
5.) Generalized neonatal infection
- resp tract, kidneys, liver, GIT, adrenals
- usually fatal
6.) Encephalitis
IBR:
- tx
- none effective; supportive ambs, nsaids
IBR:
- prevention
- isolate new additions
- dont use live vx in neonatal calves or preg cows
BSE:
- Etx?
- prion
BSE:
- Transmission?
contaminated feed w/ rendered infected cattle usually
BSE:
- This disease is REPORTABLE, what can is cause in humans?
Creutzfeld-Jakob dz
BSE:
- c/s and onset?
- onset over several months
- hyperesthesia, nervousness
- fine tremors
- persistent licking of the muzzle
BSE:
- Dx?
IHC demonstrating prion protein fibrils
BSE:
- Tx?
Cull
Bovine Lymphosarcoma:
- etx?
bovine leukemia virus
Bovine Lymphosarcoma:
- C/S
1.) CNS
- plegia, paresis, head tilt, facial paralysis, dysphagia
2.) GI
- free gas bloat, vagal indigestion, enlarged abdominal LNs, melena, thickened rectum
3.) Cardiac
4.) 25% have peripheral lymphadenopathy
5.) Exopthalmus, weight loss
Bovine Lymphosarcoma:
- dx
- ELISA = positive antibodies