Brain Tumours

Question 1

define glial cells?

Answer 1

neural cells that do not generate AP’s and have other functions.

Question 2

aka for glial cells?

Answer 2

neuroglial cells

Question 3

Oligodendrocyte

function of this cell?

Answer 3

Myelinate nerve

Question 4

Microglia

function of this cell?

Answer 4

Macrophages of CNS

Question 5

Ependymal

function of this cell?

Answer 5

Make CSF

Question 6

Astrocytes

function of this cell?
-6

Answer 6

By synapse
Regulates Ca2+
Makes BBB
Regulates K+, glutamate, Cl-

Question 7

most common types of tumour in the brain?

Answer 7

Metastases

Question 8

5 most common tumours that spread to the brain?

Answer 8

lung
breast
bowel
skin 
kidney

Question 9

most common tumour that spreads to the brain?

-1

Answer 9

lung

Question 10

most common skin tumour that spreads to the brain?

Answer 10

melanoma

Question 11

Most common 1° brain tumour?

Answer 11

glioblastoma

Question 12

2nd most common 1° brain tumour?

Answer 12

meningioma

Question 13

Tumour from 8th CN is called what?

-2 names

Answer 13

vestibular schwannoma aka acoustic schwannoma

Question 14

Most common 1° brain tumour in kids?

Answer 14

pilocytic astrocytoma

Question 15

Vestibular schwannoma is benign or cancerous?

Answer 15

benign

Question 16

Vestibular schwannoma was previously termed what?

Answer 16

acoustic neuroma

Question 17

Vestibular schwannoma arises from what nerve?

Answer 17

eighth cranial nerve

Question 18

Vestibular schwannoma is oft seen in what angle?

Answer 18

cerebellopontine angle

Question 19

Vestibular schwannoma presentation?

-3 main features

Answer 19

hearing loss, facial nerve palsy, tinnitus

Question 20

why is there facial nerve palsy in vestibular schwannoma?

Answer 20

compression of the nearby facial nerve

Question 21

Histology features of Vestibular schwannoma?

-2

Answer 21

Antoni A or B patterns

Verocay bodies

Question 22

3 treatment routes for vestibular schwannoma?

the broad idea

Answer 22

observation, radiotherapy or surgery

Question 23

The most common primary brain tumour in children?

Answer 23

pilocytic astrocytoma

Question 24

Histology of pilocytic astrocytoma?

Answer 24

Rosenthal fibres

Question 25

what is this brain tumour? aggressive paediatric brain tumour that arises within the infratentorial compartment

Answer 25

medulloblastoma

Question 26

Medulloblastoma spreads through what system?

Answer 26

CSF system

Question 27

2 treatment routes for medulloblastoma? | the broad idea

Answer 27

chemo or surgery

Question 28

Histology of medulloblastoma?

Answer 28

Small, blue cells

Question 29

which brain tumour is commonly seen in the 4th ventricle

Answer 29

ependymoma

Question 30

Histology of ependymoma?

Answer 30

perivascular pseudorosette

Question 31

which brain tumour may cause hydrocephalus?

Answer 31

ependymoma

Question 32

what brain tumour is this? Benign, slow-growing tumour common in the frontal lobes

Answer 32

oligodendroma

Question 33

histology of oligodendroma?

Answer 33

Calcifications with 'fried-egg' appearance

Question 34

Vascular tumour of the cerebellum is called what?

Answer 34

haemangioblastoma

Question 35

Haemangioblastoma is associated with what syndrome?

Answer 35

Hippel-Lindau syndrome

Question 36

Histology of haemangioblastoma?

Answer 36

foam cells and high vascularity

Question 37

benign tumours of the pituitary gland are called what?

Answer 37

Pituitary adenomas

Question 38

Pituitary adenoma has two types. what are they?

Answer 38

secretory | or non-secretory

Question 39

define secretory pituitary adenoma?

Answer 39

makes hormones in excess

Question 40

name of surgery used for pituitary adenoma?

Answer 40

transsphenoidal resection

Question 41

2 main Ix you need to order for pituitary adenoma?

Answer 41

pituitary blood profile and MRI

Question 42

high ACTH will cause what syndrome?

Answer 42

Cushing’s

Question 43

high GH will cause what syndrome?

Answer 43

acromegaly

Question 44

Compression of the optic chiasm will cause what visual field defect?

Answer 44

bitemporal hemianopia

Question 45

Most common paediatric supratentorial tumour is called what?

Answer 45

craniopharyngioma

Question 46

craniopharyngioma derives from what pouch?

Answer 46

Rathke’s pouch