Brand/Generic/MOA Flashcards
1
Q
Ranexa
- Indication/Dose
- Metabolism pathway
A
Ranolazine
- Chronic stable angina in combo w/ BB, amlodipine, or nitrate for pts w/ inadequate response to other anti-angina drugs
- D: 500 mg BID. Max 1000 mg BID
- 3A4 subtrate => inhibitor such as verapamil or diltiazem 500 mg BID max
2
Q
Monoket
ISMO
- Frequency
A
Isosorbide Mononitrate
- BID
3
Q
Nitrostat
NiroQuick
A
Nitroglycerine Sublingual
4
Q
Nitroglycerine SL
- Patient counseling poinsts
A
- Place under tongue/sit down immediately
- Take 3 in 15 min, 5 min intervals PRN.
- If not relieved after 1st dose => 911
- Cont w/ NTG until paramedics arrive
- Keep in original bottle
- Protect from light, heat, and moisture
- Keep container w/ u all the times
- If do not have SL NTG use Amyl Nitrate (X)
- Crush the cap and wave under nose
- 0.3mL inhaled as needed/may cause HA, flushing. Flammable
5
Q
Nitrolingual
NitroMist
- Indication
- Prime how many time
- Stability
A
NTG SL Spray = place under the tongue
- I: Acute Angina
- Prime: Nitrolingual = 5x; NitroMist = 10x
- Stability: Nitrolingual 2 yr; NitroMist = 3 yr
6
Q
Nitrol
NitroBid
- Brand/Indication:
A
NTG Ointment 2%
- I: Angina prophylaxis. NOT FOR ACUTE ANGINA
7
Q
Deponit Minitran Nitrodisc Nitro-Dur Transderm-Nitro
- Brand/Indication:
A
NTG Transdermal
- I: Angina prophlaxys. DO NOT use for acute attack
8
Q
Coronary Spasm
- Treatment drugs:
A
Response well to CCB and nitrates
- Verampamil
- Diltiazem
- Amlodipine
- Nicardipine
- Nifedipine
9
Q
Ranolazine(Ranexa)
- ADEs
- Cautions/CI
A
ADE
- HypoTN,
- HA, dizziness
- **QT prolonged
CI
- Hepatic cirrhosis
- 3A4 inhibitors/inducers
10
Q
Nitrate MOA
A
- Alleviates ischemic myocardial pain
- Has a dilatory effect all ALL vascular SM
- Vasodilation of coronary arteries
- Vasodilation of the peripheral arteries
- Vasodilation of venous capacitance vessels
11
Q
Nitrate indication
A
- Adm to all pt w/ suspected ischemic type pain, provided that SB is > 90 mm Hg and no other CI
12
Q
Nitrates cautions:
A
- Do not adm if SBP < 90 mm Hg => severe bradycardia or extreme tachycardia
- Use w/ caution for suspected RV infarction (right ventricular infarction => hyopTN & bradycardia
- Pts who have use viagra w/in past 24H => severe hypoTN refractory to vasopressors
13
Q
Sorbitrate
- Indication
A
Isosorbide Dinitrate chewable
- I: acute attack 3 dose in 15 min
14
Q
Isordil
- Indication
A
Isosobide dinitrate SL
- I: acute attack 3 dose in 15 min
15
Q
Isodil Titradose
- Dose
A
Isosobide dinitrate PO
- Dose: 5-10 mg TID 7am, 12pm, 5pm.
To give 10-14H free period of nitrate
