Brandon's supplemental Test 1 Cards

Question 1

Which medication is an ideal neuroprotectant and anti-convulsant, but can also cause be proconvulsant?

Answer 1

Thiopental

Question 2

Which drug is a proconvulsant and ideal for ECT?

Answer 2

methohexital

Question 3

which meds can cause centrally mediated muscle relaxation?

Answer 3

benzos

Question 4

benzos at low dose?

Answer 4

anxiolysis

Question 5

benzos at high dose

Answer 5

sedation

Question 6

Can benzos cause isoelectric EEG?

Answer 6

NO!

Question 7

Which meds decrease CMRO2 ICP and CBF?

Answer 7

Barbs
Benzos

Question 8

which meds decrease CMRO2 ICP and CPP?

Answer 8

propofol & Etomidate

Question 9

At high doses what medication can cause isoelectric EEG?

Answer 9

propofol

Question 10

which medications causes cerebral vasoconstriction?

Answer 10

propofol and etomidate

Question 11

When combined with other agents, which medication can be neuroprotectant?

Answer 11

propofol

Question 12

Which medication has no effect on CMRO2 or ICP but does decrease CBF?

Answer 12

dexmedetomidine

Question 13

Cardiac effects of benzos?

Answer 13

cardiac stable unless after induction dose, then it can decrease SVR and BP

Question 14

CV effects of propofol?

Answer 14

decrease BP, MAP, CO,
decrease SNS tone
decrase baro receptor mediated response

Question 15

CV effects of Barbituates?

Answer 15

pronounced decrease in MAP and CO, negative inotrope. Venodilation

Reflex increase in HR

Question 16

CV effects of etomidate

Answer 16

cardiac stable unless dose >0.3mg/kg, then severe drop in BP and CO

Question 17

CV effects of dexmedetomidine

Answer 17

decrease BP and HR,

can cause HTN with fast IV push of large dose

Question 18

CV effects of ketamine

Answer 18

increase everything unless endogenous catecholamines are depleted, than decrease in BP and CO can be observed

Question 19

when do you see apnea with barbs?

Answer 19

after 1-5 min

Question 20

Which medications depress the respiratory center?

Answer 20

Barbs
Benzos (mostly midazolam)
etomidate

Question 21

can brevital cause hiccups?

Answer 21

yes

Question 22

which med causes histamine release and why is that bad?

Answer 22

thiopental. Can cause bronchospasm/laryngospasm

Question 23

When do do see ventilatory response to CO2 with barbs?

Answer 23

in 6min

Question 24

What meds depress upper airway relfexes?

Answer 24

benzos. Especially with opioids

so be careful in osa and compromised airways.

Question 25

does propofol cause bronchodilation?

Answer 25

No straight from nagelhout

Question 26

when does propofol cause apnea?

Answer 26

high dose

Question 27

which drug decreases MV but ^ RR?

Answer 27

etomidate

Question 28

which meds maintain upper airway reflexes?

Answer 28

etomidate ketamine

Question 29

When does etomidate or ketamine cause apnea?

Answer 29

high dose, especially with opioids

Question 30

only induction agent that is a bronchodilator?

Answer 30

ketamine

Question 31

why is there increased risk of laryngospasm with ketamine?

Answer 31

increased salivation, so give with glycopyrolate but be careful of HR.

Question 32

Which induction agent can cause decreased airway reactivity in COPD patients?

Answer 32

precedex

Question 33

which induction agent decreases salivation?

Answer 33

precedex

Question 34

Which inducation agent is good for focal but not global injuries due to reverse steal effect

Answer 34

barbituates