bread and butter Flashcards by sophie hayton

drugs increasing lithium levels

[  ] Ace increases
[  ] Loop increases
[  ] Spiro increases
[  ] Ibuprofen increases
[  ] Mtx increases

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drugs causing gingival hyperplasia

[ ] Ccbs
[ ] Cilosporin
[ ] Phenytoin

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antidote to loperamide

naloxone

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antidote to heparins

protamine sulphate

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antidote to benzodiazepines

flumazenil

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antidote to dabigatran

idrucizumab

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antidote to apix and rivarox

andexanet alpha

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antidote to digoxin

digoxin specific antibody

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antidote for methotrexate

colonic acid

calcium foliate

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QTP?

[  ] Amiodarone
[  ] Sotalol
[  ] Macrolides
[  ] Haloperidol
[  ] Ssrus citala and escit
[  ] Tcas
[  ] Antifungals
[  ] Rlccbs
[  ] Atomoxetine
[  ] Methadone
[  ] Domperidone
[  ] Tacrolimus
[  ] All SABA/LABAs
[  ] Quinolones

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what juice does warfarin interact with

cranberry and pomegranate

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what juice does Amiodarone interact with

grapefruit

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what juice do statins interact with

grapefruit

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what juice do SSRIs interact with

grapefruit

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what juice does ciclosporin interact with

purple grape,grapefruit and pomelo

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what juice does tacrolimus interact with

grapefruit,pomelo and pomegranate

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CYP450 substrates

[  ] Statins
[  ] Amiodarone
[  ] Digoxin
[  ] Montelukast
[  ] Warfarin
[  ] Theophylline
[  ] Benzos
[  ] Ssris
[  ] Tca
[  ] Sildenafil (inhibitors)
[  ] Tamsulosin (inhibitors)
[  ] Sumatriptan

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drugs lowering seizure threshold

[  ] Theophylline 
[  ] Tramadol
[  ] Quinolones (ibuprofen)
[  ] Lithium
[  ] Antiepileptics
[  ] Orlistat
[  ] Chlorquine
[  ] Mefloquine

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drugs causing serotonin syndrome

[  ] Tramadal
[  ] Triptans
[  ] Lithium
[  ] Ssris
[  ] Tcas
[  ] Maois
[  ] Bupropion
[  ] Linezolid
[  ] Snris ( venlafaxine)

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Drugs causing SJS

[  ] Phenytoin
[  ] Carbamazepine
[  ] Lamotrigine
[  ] Galantamine
[  ] Vancomycin
[  ] Co-trimoxazole

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hepatotoxic drugs

[  ] Itraconazole and antifungals (ketaconazole the most)
[  ] Alcohol
[  ] Amiodarone
[  ] Macrolides
[  ] Benzos
[  ] Carb pheny valproa
[  ] Maoi a phenel and isocarboxazid
[  ] Atomoxetine
[  ] All tb meds except ethambutol
[  ] Flucloxicillin
[  ] Chloramphenicol
[  ] Nitrofurantoin
[  ] Tetracyclines
[  ] Terbinafine
[  ] Mtx
[  ] Sulfasalazine
[  ] Mesalazine

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drugs causing pancreatitis

[ ] Glutides
[ ] Gliptins
[ ] Valproate
[ ] Carbimazole

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drugs causing suicidal ideation

[ ] Finasteride
[ ] All antiepileptics
[ ] Atomoxetine
[ ] Varenicicline

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drugs causing neuropsychiatric reactions

[ ] Mefloquine
[ ] Isotretonoin
[ ] Montelukast
[ ] Quinolones

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checking lithium levels after?

12 hours

check digoxin levels after?

6 hours

checking gent levels (MDD and ODD)

MDD: after 3-4 doses and at dose changes ODD: 20 hours post dose

carbamazepine levels after?

1-2 weeks

theophylline levels?

4-6 hours post dose of mr formulation | 5 days after initation and 3 days after any dose changes

drugs to avoid tyramine rich foods?

MAOIs isonazid linezolid

drugs causing neuroleptic malignant syndrome?

all APs | donepezil

with or after food?

metronidazole nitrofurantoin clarithromycin MR

empty stomach

[ ] Phenoxymebthylpenicllin [ ] Tetracycline/oxyteyracyclime [ ] Flucloxicillin [ ] Azithromycin- capsules only

drugs causing ototoxicity

``` [ ] Clarightromycin and other macrolides [ ] Cisplatin [ ] Linezolid [ ] Vancomycin [ ] Vinca alkaloids [ ] Gentamicin ```

drugs causing photosensitivity

``` [ ] Doxycycline [ ] Isotretenoin [ ] Tacrolimus [ ] Amiodarone [ ] Ciclosporin [ ] Quinolones ```

drugs causing blood disorders?

``` [ ] Tacrolimus [ ] Co-trimoxazole [ ] Sulfasalazine [ ] Mesalazine [ ] antiepileptics ```

tacrolimus interacts with? (an important one)

macrolides

what colour does nitrofurantoin turn your urine

yellow brown

rifampicin colour

red

entacapone colour

brown red

traimterene colour

blue

Senna urine colour

yellow brown

chlorhexidine

stains teeth brown

POM to P?

``` PPI Chloramphenicol mometasone sildenafil maloff amrolofine sumatriptan tamsulosin tranexamic acid orlistat ```

drugs causing BMS

mycophenalate | all cytotoxic except bleomycin and vincas

drugs reducing intestinal mobility

[ ] Loperamide [ ] Codeine [ ] Metoclopramide

drug causing chug Strauss

montelukast

avoid antacids

tetracyclines quinolone bisphosphonates

drugs causing diarrhoea:

``` colchicine antibiotics laxatives magnesium ant acids digoxin ``` CALMD

Drugs causing constipation

``` al antacids AMs AHs AEs verapamil clozapine- refer ```

treating vertigo and tinnitus

betahistine

pregnancy nausea

cyclizine and prochlorperazine

treating an acute asthma attack in community

pMDI large volume spacer 4pu initially then 2 every 2 minutes for up to 10 puffs can repeat every 10 minutes- 20 minutes children: 1 pu every 30-60 seconds up to 10 puffs

breath accuated?

slow and steady over 4 s

DPI breathing

quick and deeply

pMDI breathing

slow and steady

potency of: | betametasone valerate

potent

potency of: | clobetasol propinate

very potent

potency of clobetasone butyrate

moderate

potency of hydrocortisone

mild

potency of nerisone forte?

very potent