Breast

Question 1

What is Fine-Needle Aspiration (FNA)?

Answer 1

A minimally invasive procedure used to obtain tissue samples from a breast lesion for cytological examination.

Question 2

True or False: FNA is a surgical procedure.

Answer 2

False

Question 3

What type of needle is typically used in Fine-Needle Aspiration?

Answer 3

A thin, hollow needle.

Question 4

What is the primary purpose of Fine-Needle Aspiration in breast evaluation?

Answer 4

To differentiate between benign and malignant breast lesions.

Question 5

Fill in the blank: FNA samples are primarily evaluated through ______.

Answer 5

cytology.

Question 6

What imaging techniques are often used to guide FNA procedures?

Answer 6

Ultrasound or mammography.

Question 7

What is the main advantage of using FNA over surgical biopsy?

Answer 7

It is less invasive and has a lower complication rate.

Question 8

True or False: FNA can provide information about the architecture of breast tissue.

Answer 8

False

Question 9

What is the role of cytology in the evaluation of FNA samples?

Answer 9

To examine the cellular characteristics and determine the nature of the lesion.

Question 10

What are the common indications for performing FNA on breast lesions?

Answer 10

Palpable masses, suspicious imaging findings, and lymph node involvement.

Question 11

What are the potential complications of Fine-Needle Aspiration?

Answer 11

Bleeding, infection, and pain at the site.

Question 12

Fill in the blank: FNA is often used in conjunction with ______ for comprehensive breast assessment.

Answer 12

histological analysis.

Question 13

What is the histological technique commonly used after FNA for further diagnosis?

Answer 13

Core needle biopsy.

Question 14

What cytological feature is indicative of malignancy in breast FNA samples?

Answer 14

Anisonucleosis.

Question 15

True or False: FNA can be used to evaluate both solid and cystic lesions.

Answer 15

True

Question 16

What is the typical needle gauge used in Fine-Needle Aspiration?

Answer 16

22 to 25 gauge.

Question 17

What type of lesions may be challenging to diagnose using FNA?

Answer 17

Lesions with low cellularity or cystic lesions.

Question 18

What is the significance of a ‘suspicious’ FNA result?

Answer 18

It may indicate the need for further investigation, such as a biopsy.

Question 19

Fill in the blank: FNA samples are often spread on slides for ______ staining.

Answer 19

Papanicolaou.

Question 20

What does a benign cytological finding in FNA imply?

Answer 20

The lesion is likely non-cancerous.

Question 21

What is the role of a pathologist in the FNA process?

Answer 21

To analyze the cytology slides and provide a diagnosis.

Question 22

True or False: FNA can replace surgical biopsy in all cases.

Answer 22

False

Question 23

What is the typical follow-up procedure after a suspicious FNA result?

Answer 23

A core needle biopsy or excisional biopsy.

Question 24

What are the limitations of Fine-Needle Aspiration?

Answer 24

It may not provide sufficient tissue for a definitive diagnosis in some cases.

Question 25

Fill in the blank: Adequate ______ is crucial for accurate FNA results.

Answer 25

sampling.

Question 26

What is a common cytological diagnosis for a benign breast lesion?

Answer 26

Fibroadenoma.

Question 27

What does the term 'cytologic atypia' refer to?

Answer 27

Abnormalities in cell size, shape, and organization.

Question 28

How does FNA compare to core needle biopsy in terms of invasiveness?

Answer 28

FNA is less invasive than core needle biopsy.

Question 29

What is the importance of patient history in the FNA process?

Answer 29

It helps in assessing risk factors and guiding the procedure.

Question 30

Fill in the blank: The ______ of the needle can affect the quality of the sample obtained.

Answer 30

size.

Question 31

What is the recommended follow-up for a benign FNA result?

Answer 31

Regular monitoring and clinical examination.

Question 32

True or False: FNA is effective for diagnosing inflammatory breast conditions.

Answer 32

True

Question 33

What is the typical turnaround time for FNA results?

Answer 33

1 to 2 days.

Question 34

What is the main disadvantage of FNA in breast cancer diagnosis?

Answer 34

It may yield insufficient tissue for molecular testing.

Question 35

Fill in the blank: FNA is often performed in an ______ setting.

Answer 35

outpatient.

Question 36

What are the common cellular features of invasive carcinoma seen in FNA?

Answer 36

Increased nuclear-to-cytoplasmic ratio and irregular nuclear contours.

Question 37

What is the role of imaging in conjunction with FNA?

Answer 37

To locate and characterize the lesion prior to aspiration.

Question 38

True or False: FNA can be performed without imaging guidance.

Answer 38

True

Question 39

What is the typical follow-up for a malignant FNA result?

Answer 39

Further imaging and possible surgical intervention.

Question 40

What type of breast lesions is FNA particularly useful for?

Answer 40

Palpable masses and suspicious lesions.

Question 41

Fill in the blank: The success of FNA is highly dependent on the ______ technique used.

Answer 41

sampling.

Question 42

What is the key benefit of using ultrasound guidance during FNA?

Answer 42

Improved accuracy in targeting the lesion.

Question 43

What might a 'negative' FNA result indicate?

Answer 43

No malignant cells were detected, but further evaluation may be needed.

Question 44

True or False: FNA can help in the diagnosis of metastatic breast cancer.

Answer 44

True

Question 45

What is a common cytological feature of a benign cystic lesion in FNA?

Answer 45

Simple fluid with few cells.