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Flashcards in Breast Deck (40):
1

most common site of axillary lymph node metastases

lateral

2

most common site of metastasis

bone, lung, pleura, liver

3

carcinoma in situ associated with bilaterality

LCIS

4

common carcinoma in situ in premenopausal women

LCIS

5

True or false: tamoxifen and raloxifene are effective against DCIS and LCIS

raloxifene is NOT effective against DCIS and LCIS

6

surveillance for (+) BRCA: breast exam every __ months and mammography every __ months starting at age __

breast exam every 6 months and mammography every 12 months starting at age 25

7

annual mammographic screening starting at age

40

8

True or false: DCIS and LCIS are anatomic precursors

LCIS is not an anatomic precursor

9

True or false: for DCIS, mastectomy and lumpectomy with adjuvant radiotherapy have similar mortality rate

true

10

True or false: for DCIS, mastectomy and lumpectomy with adjuvant radiotherapy have similar rates of local recurrence

lumpectomy with adjuvant radiotherapy has higher rate of local recurrence

11

Differential diagnosis for Paget's disease of the nipple, and how to differentiate

Paget's disease: (+) CEA
superficial spreading melanoma: (+) S-100

12

where are the Paget cells located in the skin?

rete pegs

13

Signet ring cells and Indian file configuration are found in what type of breast cancer?

invasive lobular carcinoma

14

True or false: invasive lobular carcinomas are unilateral

multifocal, multicentric and bilateral

15

Medullary carcinoma can mimic

fibroadenoma

16

Medullary carcinoma is associated with BRCA 1 or BRCA 2?

BRCA 1

17

Mammography: visualizes upper outer quadrant and axillary tail of Specne

mediolateral oblique

18

Mammography: visualizes medial aspect of breast

craniocaudal

19

Mammography: images the greatest volume of breast tissue

mediolateral oblique

20

Mammography: permits greater breast compression

craniocaudal

21

Mammographic mimickers of breast cancer

radial scars, fibromatosis, granular cell tumor, fat necrosis

22

True or false: multifocality is a contraindication to breast conservation surgery

Multicentricity
Prior radiation therapy to the breast or chest wall
Involved surgical margins or unknown margin status after re-excision
Scleroderma or lupus erythematosus

23

Treatment: Her-2/neu (+)

doxorubicin, cyclophosphamide, paclitaxel

24

Treatment: Her-2/neu (-)

trastuzumab

25

Treatment: breast cancer in second trimester of pregnancy

MRM

26

Treatment: breast cancer in third trimester of pregnancty

lumpectomy with axillary node dissection

27

Most common type of male breast cancer

DCIS

28

Metastasis in cystosarcoma phylloides

vascular

29

True or false: cystosarcoma phylloides spreads to axillary lymph nodes

cystosarcoma phylloides DOES NOT spread to axillary lymph nodes

30

Rotter's node

interpectoral group (level II)

31

Gynecomastia: (+) redundancy

Grade III

32

Malignant risk of sclerosing adenosis and intraductal papilloma

none

33

True or false: cancers associated with BRCA1 are well differentiated and hormone receptor positive

poorly differentiated and hormone receptor negative

34

True or false: cancers associated with BRCA1 are unilateral

bilateral

35

True or false: cancers associated with BRCA2 are well differentiated and hormone receptor positive

true

36

True or false: papillary breast carcinoma have high rate of axillary metastasis

low rate

37

true or false: breast pain is associated with cancer

benign disease

38

chemotherapy for breast cancer

doxorubicin-containing

39

Most common subtype:
A. ER+ and/or PR+, HER2-
B. ER+ and/or PR+, HER2+
C. ER-, HER2+
D. ER-, PR-, HER2-

ER+ and/or PR+, HER2-

40

True or false: cystosarcoma phyllodes are poorly demarcated

well-demaracted