Breast

Question 1

most common site of axillary lymph node metastases

Answer 1

lateral

Question 2

most common site of metastasis

Answer 2

bone, lung, pleura, liver

Question 3

carcinoma in situ associated with bilaterality

Answer 3

LCIS

Question 4

common carcinoma in situ in premenopausal women

Answer 4

LCIS

Question 5

True or false: tamoxifen and raloxifene are effective against DCIS and LCIS

Answer 5

raloxifene is NOT effective against DCIS and LCIS

Question 6

surveillance for (+) BRCA: breast exam every __ months and mammography every __ months starting at age __

Answer 6

breast exam every 6 months and mammography every 12 months starting at age 25

Question 7

annual mammographic screening starting at age

Answer 7

40

Question 8

True or false: DCIS and LCIS are anatomic precursors

Answer 8

LCIS is not an anatomic precursor

Question 9

True or false: for DCIS, mastectomy and lumpectomy with adjuvant radiotherapy have similar mortality rate

Answer 9

true

Question 10

True or false: for DCIS, mastectomy and lumpectomy with adjuvant radiotherapy have similar rates of local recurrence

Answer 10

lumpectomy with adjuvant radiotherapy has higher rate of local recurrence

Question 11

Differential diagnosis for Paget’s disease of the nipple, and how to differentiate

Answer 11

Paget’s disease: (+) CEA

superficial spreading melanoma: (+) S-100

Question 12

where are the Paget cells located in the skin?

Answer 12

rete pegs

Question 13

Signet ring cells and Indian file configuration are found in what type of breast cancer?

Answer 13

invasive lobular carcinoma

Question 14

True or false: invasive lobular carcinomas are unilateral

Answer 14

multifocal, multicentric and bilateral

Question 15

Medullary carcinoma can mimic

Answer 15

fibroadenoma

Question 16

Medullary carcinoma is associated with BRCA 1 or BRCA 2?

Answer 16

BRCA 1

Question 17

Mammography: visualizes upper outer quadrant and axillary tail of Specne

Answer 17

mediolateral oblique

Question 18

Mammography: visualizes medial aspect of breast

Answer 18

craniocaudal

Question 19

Mammography: images the greatest volume of breast tissue

Answer 19

mediolateral oblique

Question 20

Mammography: permits greater breast compression

Answer 20

craniocaudal

Question 21

Mammographic mimickers of breast cancer

Answer 21

radial scars, fibromatosis, granular cell tumor, fat necrosis

Question 22

True or false: multifocality is a contraindication to breast conservation surgery

Answer 22

Multicentricity
Prior radiation therapy to the breast or chest wall
Involved surgical margins or unknown margin status after re-excision
Scleroderma or lupus erythematosus

Question 23

Treatment: Her-2/neu (+)

Answer 23

doxorubicin, cyclophosphamide, paclitaxel

Question 24

Treatment: Her-2/neu (-)

Answer 24

trastuzumab

Question 25

Treatment: breast cancer in second trimester of pregnancy

Answer 25

MRM

Question 26

Treatment: breast cancer in third trimester of pregnancty

Answer 26

lumpectomy with axillary node dissection

Question 27

Most common type of male breast cancer

Answer 27

DCIS

Question 28

Metastasis in cystosarcoma phylloides

Answer 28

vascular

Question 29

True or false: cystosarcoma phylloides spreads to axillary lymph nodes

Answer 29

cystosarcoma phylloides DOES NOT spread to axillary lymph nodes

Question 30

Rotter's node

Answer 30

interpectoral group (level II)

Question 31

Gynecomastia: (+) redundancy

Answer 31

Grade III

Question 32

Malignant risk of sclerosing adenosis and intraductal papilloma

Answer 32

none

Question 33

True or false: cancers associated with BRCA1 are well differentiated and hormone receptor positive

Answer 33

poorly differentiated and hormone receptor negative

Question 34

True or false: cancers associated with BRCA1 are unilateral

Answer 34

bilateral

Question 35

True or false: cancers associated with BRCA2 are well differentiated and hormone receptor positive

Answer 35

true

Question 36

True or false: papillary breast carcinoma have high rate of axillary metastasis

Answer 36

low rate

Question 37

true or false: breast pain is associated with cancer

Answer 37

benign disease

Question 38

chemotherapy for breast cancer

Answer 38

doxorubicin-containing

Question 39

``` Most common subtype: A. ER+ and/or PR+, HER2- B. ER+ and/or PR+, HER2+ C. ER-, HER2+ D. ER-, PR-, HER2- ```

Answer 39

ER+ and/or PR+, HER2-

Question 40

True or false: cystosarcoma phyllodes are poorly demarcated

Answer 40

well-demaracted