Breast

Question 1

Limits of Radical Mastectomy (Halsted)

Answer 1

Superiorly - Clavicle
Inf - sheath covering abdominal wall muscles
Medial - Midsternum
Lateral - Subscapularis or Latissimus dorsi
Deeper - P. Major and minor

Question 2

Absolute contraindications BCT

Answer 2

Pregnancy except 3rd trimester
Persistently positive margin
Multicentricity
History of radiation exposure

Question 3

Contraindications of Sentinel Node Biopsy

Answer 3

Palpable LN
Axillary surgery
RT to breast or axilla
Multicentric lesion

Question 4

Risk factors breast carcinoma

Answer 4

Age 
Female
Family
LCIS
atypical hyperplasia - ductal - Lobular
Proliferative breast disease 
Mammographically dense breast

Increased estrogen 
Endogenous
Early menarche
Nulliparity
Late first full term pregnancy 
Obesity (postmenopausal)

Question 5

Relative contraindications of BCT

Answer 5

Connective tissue disorders
SLE and Scleroderma- absolute
RA not a C/I

Lump to breast ratio high
Lump just below nipple areolar complex
Inability to lie supine
Severe cardiac disease for left sided Ca breast
Severe COPD
Lump in pendulous breast
Patient from far flung areas

Question 6

Risk factors of Male breast cancer

Answer 6

Age
Family history
BRCA2
cryptoorchidism
Testicular atrophy
Klinefelter
Testicular feminising syndrome
Cirrhossis
High fatty diet

Question 7

Features of malignancy on USG IN BREAST

Answer 7

Hypoechoic
Taller than wider cells
Central vascularity

Question 8

Proliferative benugn breast disorder with no risk of malignancy

Answer 8

Sclerosing adenosis

Intraductal papilloma

Question 9

Tamoxifen indications

Answer 9

ER/PR positive
Recurrence decrease
Contralateral involvement prevention