breast benign and cystic 01-20

Question 1

what 4 benign/fibrocystic changes?

Answer 1

fibrocystic change
intraductal papilloma
fobroadenoma
phylloides tumor

Question 2

1. Fibrocystic change. definition?

Answer 2

Development of fibrosis and cysts in the breast

Question 3

Development of fibrosis and cysts in the breast?

Answer 3

1. Fibrocystic change.

Question 4

1. Fibrocystic change. in what population?

Answer 4

most common change in the PREMENOPAUSAL breast; thought to be hormone mediated

Question 5

1. Fibrocystic change. presentation?

Answer 5

vague irregularity of the breast tissue (,lumpy breast’), usually in the upper outer quadrant

Question 6

1. Fibrocystic change. gross exam?

Answer 6

Cysts have BLUE-DOME appearance on gross exam

Question 7

vague irregularity of the breast tissue (,lumpy breast’), usually in the upper outer quadrant?

Answer 7

1. Fibrocystic change.

Question 8

1. Fibrocystic change. cancerous?

Answer 8

benign, but some changes are associated with increased risk for invasive carcinoma (increased risk applies for both breasts)

Question 9

1. Fibrocystic change. Which change does not increase risk for cancer?

Answer 9

fibrosis, cysts, and apocrine metaplasia

Question 10

1. Fibrocystic change. fibrosis, cysts, and apocrine metaplasia - risk for cancer?

Answer 10

no risk

Question 11

1. Fibrocystic change. what increases 2x risk for cancer?

Answer 11

Ductal hyperplasia and sclerosing adenosis

Question 12

1. Fibrocystic change. Ductal hyperplasia and sclerosing adenosis what risk for cancer?

Answer 12

2x risk

Question 13

1. Fibrocystic change. what increases 5x risk?

Answer 13

atypical hyperplasia

Question 14

1. Fibrocystic change.atypical hyperplasia what risk?

Answer 14

5x

Question 15

2. Intraductal papilloma. definition?

Answer 15

papillary growth, usually into a large duct

Question 16

papillary growth, usually into a large duct?

Answer 16

2. Intraductal papilloma.

Question 17

2. Intraductal papilloma. morphology?

Answer 17

fibrovascular projections lined by epithelial (luminal) and myoepithelial cells

Question 18

fibrovascular projections lined by epithelial (luminal) and myoepithelial cells?

Answer 18

2. Intraductal papilloma.

Question 19

2. Intraductal papilloma. presentation?

Answer 19

bloody nipple discharge in a PREmenopausal woman

Question 20

bloody nipple discharge in a PREmenopausal woman?

Answer 20

2. Intraductal papilloma.

Question 21

2. Intraductal papilloma. from what other must be distinguished?

Answer 21

papillary CARCINOMA, which also presents as bloody nippe discharge

Question 22

2. Intraductal papilloma. diff. from papillary carcinoma?

Answer 22

1. papillary carcinoma is characterized by fibrovascular projections lined by epithelial cells without underlying myoepithelial cells.
2. Pap. carcinoma increases with age, thus more common in POSTmenopausal women.

Question 23

2. Intraductal papilloma AKA papillary tumor

Answer 23

.

Question 24

3. Fibroadenoma. definition?

Answer 24

Tumor of fibrous tissue and glands

Question 25

Tumor of fibrous tissue and glands?

Answer 25

3. Fibroadenoma.

Question 26

3. Fibroadenoma. prevalence and in what population?

Answer 26

most common benign neoplasm of the breast. seen in PREmenopausal women

Question 27

most common benign neoplasma of the breast?

Answer 27

3. Fibroadenoma.

Question 28

3. Fibroadenoma. presentation?

Answer 28

well-circumscribed, mobile, marble-like mass, painless

Question 29

well-circumscribed, mobile marble-like mass?

Answer 29

3. Fibroadenoma.

Question 30

3. Fibroadenoma. risk for cancer?

Answer 30

no risk

Question 31

3. Fibroadenoma. sensitive to what?

Answer 31

estrogen sensitive - grows during pregnancy and may be painful during the menstrual cycle

Question 32

estrogen sensitive - grows during pregnancy and may be painful during the menstrual cycle?

Answer 32

3. Fibroadenoma.

Question 33

4. Phylloides tumor. morphology?

Answer 33

fibroadenoma-like tumor with overgrowth of the fibrous component.

Question 34

4. Phylloides tumor. biopsy?

Answer 34

,,leaf-like" projections on biopsy

Question 35

,,leaf-like" projections on biopsy?

Answer 35

4. Phylloides tumor.

Question 36

4. Phylloides tumor. in what population?

Answer 36

POSTmenopausal women

Question 37

4. Phylloides tumor. risk for malignancy?

Answer 37

can be malignant in some cases.

Question 38

UW. Fibroadenoma. Age?

Answer 38

15-35 (PREMENOPAUSAL)

Question 39

UW. Fibroadenoma. which side?

Answer 39

can occur as multiple/bilateral leasions

Question 40

UW. Fibroadenoma increase when?3

Answer 40

during pregnancy, lactation or with estrogen therapy

Question 41

UW. Fibroadenoma histology?

Answer 41

benign-appearing cellular or myxoid stroma that encircles epithelium-lined glandular and cystic spaces.

Question 42

benign-appearing cellular or myxoid stroma that encircles epithelium-lined glandular and cystic spaces?

Answer 42

Fibroadenoma

Question 43

UW. Mammary ductal ectasia. Histopathology?

Answer 43

Ductal dilation, breast secretion and CHRONIC granulomatous inflammarion in the periductal and interstitial areas. Cells: PLASMA CELLS, lymphocytes, histiocytes, foamy macrophages (biski papildziau is pathology outlines)

Question 44

Ductal dilation, breast secretion and CHRONIC granulomatous inflammarion in the periductal and interstitial areas. Cells: PLASMA CELLS, lymphocytes, histiocytes, foamy macrophages

Answer 44

UW. Mammary ductal ectasia.

Question 45

UW. Sclerosing adenosis - what is it?

Answer 45

fibrocytic change, that increases risk for invasive carcinoma 2x

Question 46

UW. Sclerosing adenosis histology?

Answer 46

Central acinar proliferation and compression with surrounding fibrotic tissue and peripheral ductal dilation.

Question 47

Central acinar proliferation and compression with surrounding fibrotic tissue and peripheral ductal dilation?

Answer 47

UW. Sclerosing adenosis