Breast Cancer Flashcards
(7 cards)
1
Q
Approach for a patient with breast lump
A
Clinical Exam with imaging
US +/- Mammogram
FNAC/B
(fine needle aspiration cytology/biopsy)
2
Q
Features that make you suspicious of a malignant lump
A
Irregular & Hard Fixed to chest wall Skin above is tethered Palpable axillary lymph nodes Indrawn nipple/nipple involvement Bone tenderness/pain
3
Q
Fibroadenoma
A
Benign Breast Tumour
4
Q
What does calcification indicate during a mammogram
A
Benign Tumour
5
Q
Mastectomy
A
Full removal of breast
6
Q
Factors affecting Tumour Progosis
A
Tumour Size Lymph Node Stage Histological Type Histological Grade Vascular Invasion Excision Margins In situ component Hormone & HER2 Receptor Status
7
Q
HER2 Receptor
A
Receptors on breast cells
Normally, they help control how a breast cell grows, divides, and repairs itself
In some breast cancers, the HER2 gene doesn’t work correctly and makes too many copies of itself