Breast pathophys Flashcards

(34 cards)

1
Q

What allows for breast mobility

A

retromammary space

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2
Q

What types of tissue make up the breast

A

glandular
fibrous
fatty (makes up the bulk)

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3
Q

What is the name of the ducts that attach to the lobules of the mammary glands

A

lactiferous

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4
Q

What is the job of lactiferous ducts

A

carry milk that is produced in the glandular tissue to the nipple

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5
Q

What protects the nipple during breast feeding

A

Sebaceous glands that produce oily secretions

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6
Q

Where does the venous drainage from the breast occur

A

primarily the axillary vein

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7
Q

Where does the lymphatic fluid of the breast collect

A

subareolar lymphatic plexus

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8
Q

Where does most the lymphatic fluid of the breast drain

A

Axillary lymph nodes

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9
Q

How does estrogen effect breast development

A

encourages ductal growth and fat distribution

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10
Q

How does progesterone effect breast development

A

gland growth and develop the functional cells within the acini

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11
Q

What are the functional units of the breast

A

Acini

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12
Q

What is responsible for contraction to cause ejection of milk

A

Myoepithelial cells under the acini cells

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13
Q

What is the first sign of puberty for women

A

breast development

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14
Q

How long does it take breasts to fully develop

A

4 years

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15
Q
A
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16
Q

What hormone stimulates milk production

17
Q

What hormone stimulates milk letdown

18
Q

What causes premenstrual breast fullness and discomfort

A

progesterone causing dilation of the ducts

19
Q

What hormone stimulates milk letdown

20
Q

When does breast growth stop

A

around age 35

21
Q

Where is milk made and secreted from after birth

A

alveolar lumen

22
Q

What is the first milk produced after delivery

23
Q

What is important about colostrum

A

Contains immunologic components

24
Q

Where are fibrocystic changes typically felt in the breast

A

upper/outer breast tissue

25
When are fibrocystic breast changes most common
women of child bearing years
26
How is a fibroadenoma described
firm, mobile, painless and typically 1-3cm in diameter typically solitary
27
What is a fibroadenoma
overgrowth of epithelial and supporting structural cells
28
What is the main difference between fibroadenomas and fibrocystic changes
Fibroadenomas are not under monthly hormonal influence so it will have slow growth
29
When does mastitis typically occur
m/c in the first 3 months of lactation
30
What is mastitis associated with
decreased milk ejection d/t infrequent feedings nipple damage weaning rapidly oversupply of milk blockage of duct tree/fatigue
31
When should mastitis be worked up for infectious etiology
if it persists 12-24 hours
32
What is a breast abscess
complication of mastitis or cellulitis with formation of a pocket of purulent fluid
33
What is the most common cause of galactorrhea
hyperprolactinemia
34
What causes paraneoplastic syndrome
small cell lung cancer