BRS + GH Flashcards

1
Q

Which of the following substances is released from neurons in the GI tract and produces smooth muscle relaxation?

A. Secretin
B. Gastrin
C. CCK
D. VIP
E. GIP
A

D. VIP

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2
Q

Which of the following is the site of secretion of intrinsic factor?

A. Gastric antrum
B. Gastric fundus
C. Duodenum
D. Ileum
E. Colon
A

B. Gastric fundus

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3
Q

Which of the following abolishes “receptive relaxation” of the stomach?

A. Parasympathetic stimulation
B. Sympathetic stimulation
C. Vagotomy
D. Administration of gastrin
E. Administration of VIP
F. Administration of CCK
A

C. Vagotomy

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4
Q

Micelle formation is necessary for the intestinal absorption of:

A. Glycerol
B. Galactose
C. Leucine
D. Bile acids
E. Vitamin B12
F. Vitamin D
A

F. Vitamin D

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5
Q

Which of the following changes occurs during defecation?

A. Internal anal sphincter relaxed
B. External anal sphincter contracted
C. Rectal smooth muscle relaxed
D. Intra-abdominal pressure is lower than when at rest
E. Segmentation contractions predominate
A

A. Internal anal sphincter relaxed

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6
Q

Which of the following is true about secretion from the exocrine pancreas?

A. It has a higher Cl concentration than does plasma
B. It is stimulated by the presence of HCO3 in the duodenum
C. Pancreatic HCO3 secretion is increased by gastrin
D. Pancreatic enzyme secretion is increased by CCK
E. It is hypotonic

A

D. Pancreatic enzyme secretion is increased by CCK

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7
Q

A pt with a duodenal ulcer is treated successfully cimetidine. The basis for cimetidine’s inhibition of gastric H secretion is that it

A. Blocks muscarinic receptors on parietal cells
B. Blocks H2 receptors on parietal cells
C. Increases intracellular cAMP levels
D. Blocks H,K-ATPase
E. Enhances action of ACh on parietal cells

A

B. Blocks H2 receptors on parietal cells

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8
Q

A 49 y/o patient with severe Crohn’s disease has been unresponsive to drug therapy and undergoes ileal resection. After the surgery, he will have steatorrhea because

A. The liver bile acid pool increases
B. Chylomicrons do not form in the intestinal lumen
C. Micelles do not form in the intestinal lumen
D. Dietary TAGs cannot be digested
E. The pancreas does not secrete lipase

A

C. Micelles do not form in the intestinal lumen

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9
Q

Which of the following substances is secreted in response to an oral glucose load?

A. Secretin
B. Gastrin
C. CCK
D. VIP
E. GIP
A

E. GIP

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10
Q

Which of the following is not normally foundin abundance in the portal blood?

A. Amino acids
B. Glucose
C. Short chain fatty acids
D. Triglycerides

A

D. Triglycerides

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11
Q

A 19 y/o female complains of diarrhea, nausea, light headedness, and flatulence. The physician administers 50 g of oral lactose at time zero, and measures breath hydrogen every 30 min for 3 hrs. The results indicate a rise in hydrogen ions over time with a peak at 3 hrs. Which of the following best describes the patient’s condition?

A. Brush border lactase deficiency
B. Brush border lactase excess
C. Decreased pancreatic lactase
D. Increased pancreatic lactase
E. No digestive abnormality
A

C. Decreased pancreatic lactase

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12
Q

Compared to plasma, saliva has the highest relative concentation of which of the following ions under basal conditions?

A. Bicarbonate
B. Chloride
C. Potassium
D. Sodium

A

C. Potassium

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13
Q

Which of the following ions has the highest concentration in saliva under basal conditions?

A. Bicarbonate
B. Chloride
C. Potassium
D. Sodium

A

A. Bicarbonate

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14
Q

Biopsies are taken from the antral and duodenal mucosa of a 65 y/o woman. Which of the following hormones can be found in tissue homogenates from both locations?

A. CCK
B. GLIP
C. Gastrin
D. Motilin
E. Secretin
A

C. Gastrin

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15
Q

A 10 y/o boy consumes a cheeseburger, fries, and chocolate shake. The meal stimulates the release of several GI hormones. The presence of fat, carbs, or protein in the duodenum stimulates the release of which of the folllowing hormones from the duodenal mucosa?

A. CCK
B. GLIP
C. Gastrin
D. Motillin
E. Secretin
A

B. GLIP

[glucose dependent insulinotropic peptide]

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16
Q

Which of the following factors can inhibit gastric acid secretion?

A. GLIP, nervous reflexes
B. Secretin
C. Secretin, enterogastrones
D. Somatostatin, enterogastrones, nervous reflexes
E. Somatostatin, GLIP
F. Somatostatin, secretin, GLIP, enterogastrones, nervous reflexes

A

F. Somatostatin, secretin, GLIP, enterogastrones, nervous reflexes

17
Q

Gastric emptying is tightly regulated to ensure that chyme enters the duodenum at an appropriate rate. Which of the following events promotes gastric emptying under normal physiological conditions in a healthy person? (In order of tone of orad stomach, segmentation contractions in SI, tone of pyloric sphincter)

A. Decrease, decrease, decrease
B. Decrease, increase, decrease
C. Increase, decrease, decrease
D. Increase, decrease, increase
E. Increase, increase, increase
A

C. Increase, decrease, decrease