Brucellosis And Typhoid Fever Flashcards
(29 cards)
Brucella is gram?
Negative + intracelular
The animal reservoir:
Goats
Sheep
Camels
B. Melitensis
Cows , buffalo
B. Abortus
Pigs
B. Suis
Ingestion of raw milk and undercooked meat leads to?
Brucellosis
IP of brucella is?
5 days to 3 months
The commonest clinical manifestation of brucellosis is?
Undulant fever (intermittent + variable duration)
Which of the following is NOT a complication of brucellosis?
- Arthritis.
- Spondylitis.
- Osteomyelitis.
- Epididymo-orchitis.
- Chronic fatigue.
- Liver failure.
Liver failure
The most specific test of brucellosis?
Blood culture
Titres of non endemic areas of brucellosis?
> 1:160
Titres of endemic areas of brucellosis?
> 1:320
Typhoid fever is caused by?
Salmonella enterica
Transmitted by close contact or ingestion of contaminated food or water?
Typhoid fever
IP of salmonella enterica ?
5 to 21 days
Raising fever + chills + constipation occurs in which week of typhoid fever illness?
1st week
Abdominal pain and “rose spots” are seen in?
2nd week of typhoid fever
excretion of the organism in stool or urine >12 months after acute infection.
Chronic salmonella carriage
The most sensitive routinely available diagnostic tool of typhoid fever?
BM culture
Chronic salmonella carriage should be treated with?
4 weeks of fluoroquinolone
Doxycycline + rifampicin for 6 months are used to treat?
- Brucellosis.
- Typhoid fever.
- TB.
- HIV.
Brucellosis
Used for preventing relapse of brucellosis?
- Doxycycline 6w + streptomycin 2-3w.
- Doxycycline 2-3w + streptomycin 6w.
A
Which of the following can be used as a substitute for streptomycin in the Tx of brucellosis?
- Primaquine.
- Cephalosporins.
- Gentamicin.
- Vancomycin.
Gentamicin
Pregnant women with brucellosis is treated with?
Rifampicin alone or with TMP-SMX
Has three surface antigens O,H and Vi.
Salmonella
