Brunner: genetic mutations (Biological) Flashcards

1
Q

Method?

A

Quasi natural/ correlation

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2
Q

Sample?

A

5 affected males within one Netherland family

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3
Q

Procedure?

A

Data collected from analysis of urine samples over 24 hours and an IQ test

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4
Q

Results?

A
  • all had mental retardation (mean IQ under 85)
  • urine tests= lack of enzyme MOAO
  • DNA: mutation identified in X chromosome (gene responsible for producing MAOA)
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5
Q

Possible explanation?

A
  • MAOA involved in serotonin metabolism (neurotransmitter involved in anger and aggression)
  • Males had abnormally high levels of serotonin in which could have made them resistant
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6
Q

Conclusions?

A
  • gene mutations can be responsible for aggressive behaviour, could lead to criminal
  • defect in gene led to MAOA deficiency
  • may account for inability for males to regulate aggression
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7
Q

Strengths?

A
  • urine samples= objective+support psychology as a science
  • ecologically valid as didn’t create the aggressive tendencies
  • standardised= internal reliability
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8
Q

Weaknesses?

A
  • urine samples= don’t offer cause and effect
  • reductionist as doesn’t take nurture into account
  • low population validity= cannot generalise to wider population
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9
Q

Aim?

A

To explain the behaviour of a large family in the Netherlands where the males are affected by mental retardation and abnormal violent behaviour

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