BS Flashcards

(57 cards)

1
Q

Carbohydrates- RDA

A
  • 130 g/d
  • 520 kcal/d
  • 45-65% diet
  • Amount of glucose required for brain to support normal physiological function
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2
Q

Fiber- RDA

A
  • 14 g/100kcal
  • More for men than women
  • GI, DM, benefits
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3
Q

Simple sugars- RDA

A
  • Part of the carbohydrate intake

- < 30-50 g of sugar

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4
Q

Protein- RDA

A
  • 45-56 g/d

- 10-30%

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5
Q

Thiamine- phys fxn

A
  • Cofactor for enzymes in cellular glucose and amino acid metabolism
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6
Q

Thiamine- RDA

A
  • 1.2-1.1 mg/d

- No know adverse effect for taking in excess

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7
Q

Riboflavin- phys fxn

A
  • Coenzyme in oxidation/ reduction reaction- FMN & FAD

- Required for fatty acid oxidation and mitochondrial electron transport- ATP from glucose

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8
Q

Riboflavin- RDA

A
  1. 3-1.1 mg/d

- No upper limit

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9
Q

Niacin- phys fxn

A
  • Precursor for NAD/ NADP
  • Involved in energy metabolism pathway
  • Catabolism of fatty acids & glycolysis
  • Synthesis for cholesterol, DNA, RNA
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10
Q

Niacin- RDA

A

16-14 mg/ day

- Max 35 mg/day to avoid flushing

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11
Q

Pantothenic acid- phys fxn

A
  • CoA- brings acetyl coA into citric acid cycle

- Fatty acid oxidation

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12
Q

Pantothenic acid- AI

A
  • Not enough evidence for RDA

- 5 mg/d

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13
Q

Pyridoxine- phys fxn

A
  • Involved in amino acid metabolism

- Heme biosynthesis

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14
Q

Pyridoxine- RDA

A
  • 1.3 mg/d
  • UL: 100 mg/d
  • High intake- sensory neuropathy
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15
Q

Biotin- phys fxn

A

Facilities energy metabolism- fatty acid synthesis, gluceogenesis

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16
Q

Biotin- AI

A

30 mcg/d

- No upper limit

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17
Q

Cyanocobalamin- phys fxn

A
  • Methionine synthase- methylation rxns, Roxy of fatty acids

- RBC formation and maturation

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18
Q

Cyanocobalamin- RDA

A
  • Risk of vegans/ vegetarians- no plant based

- 2.4 mcg/day

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19
Q

Folate- phys fxn

A

Facilitates DNA replication, Turning genes on and off

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20
Q

Folate- RDA

A
  • 400 mcg/day
  • Max: 1000 mcg/day
  • Important in pregnancy- neural tube defects
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21
Q

Vit C- phys fxn

A
  • Cellular antioxidant
  • Neutralizes free radicals
  • Enhances iron absorption
  • Collagen formation & stability- wound healing, bleeding gums, petechiae
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22
Q

Vit C- RDA

A
  • 75 - 90 mg/day
  • Smokers +35mg/day due to increased free radicals
  • UL: 2000 mg/day
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23
Q

Vit A- fxn

A
  • Vision

- Gene transcription: reprodcution, immune, embryonic,

24
Q

Vit A- RDA

A
  • 700-900 mcg retinol activity equivalents
  • UL: 10,000 iu, 3,000 RAE
    Upper limit can cause birth defects in pregnancy
25
Vit D- fxn
- Helps body absorb calcium | - Gene transcription
26
Vit D- RDA
600 IU/day | - UL: 4,000 IU/day
27
Vit E- fxn
- lipid soluble antioxidant | - integrity of biological membranes
28
Vit E- RDA
15 mg | - UL: 1000 mg
29
Vit K- fxn
- Allows normal blood clotting | - AI 90-120 mg/day
30
Hormone of satiety: Ghrelin
- Produced in stomach - When elevated stimulates appetite - Decreased initiates satiety
31
Hormone of satiety: Leptin
- Produced in adipocytes & stimulates hypothalamus | - Initiates satiety
32
Hormone of satiety: Orexin
- Stimulates food craving, arousal and wakefulness - Increased by ghrelin & hypoglycemia - Narcolepsy - Inhibited by leptin
33
Thiamine deficiency- Eti
- Due to alcoholism
34
Thiamine deficiency- Sx
- Anorexia, muscle cramps, paresthesia & irritability - Wet beriberi- high output HF - Dry beriberi- Pain, paresthesia and loss of reflex
35
Thiamine deficiency- Dx
- Clinical response to thiamine supplementation | - Urinary thiamine excretion
36
Thiamine deficiency- Tx
Large parenteral thiamine doses
37
Riboflavin deficiency- Eti
- occur in combination with other deficiencies due to undernutrition and medication interactions
38
Riboflavin deficiency- Sx
- Cheilosis - Angular stomatitis - Glossitis - Seborrrheic dermatitis - Corneal vascularization - Anemia
39
Riboflavin deficiency- Dx
- Measurement of erythrocyte reductase and serum levels
40
Riboflavin deficiency- Tx
- Empirical treatment through nutrition & oral supplements
41
Niacin- Eti
- alcoholism, nutrient- drug interactions, inborn errors of metabolism
42
Niacin- Sx
- Traid of pellagra: dermatitis (dark, dry and scaling), diarrhea & dementia
43
Niacin- Dx
- Urine test | - Clinical
44
Niacin- Tx
Oral niacin
45
Vit B 6- Eti
Medication interactions - Alcoholism - Immunodeficiency
46
Vit B 6- Sx
- mouth soreness, glossitis, cheilosis, weakness, and irritability - Peripheral neuropathy, anemia, seizures
47
Vit B 6- Dx
Pyridoxal phosphate levels in blood
48
Vit B 6- Tx
- Oral supplementation
49
Vit C- Eti
- Dietary inadequacy in urban poor, elderly & chronic alcoholism - Cigarettes, CKD & CA
50
Vit C- Sx
- Malaise & weakness - Scurvy: Petechiae, bleeding gums, perifollicular hy[erkeratotic papules - Edema, oliguria & neuropathy
51
Vit C- Dx
Clinically based on skin lesions - Atraumatic hemearthrosis - Decreased plasma levels
52
Vit C- Tx
Ascorbic acid, improvement occurs within days
53
Vit A- Eti
Most common- elderly & urban poor - Common cause of blindness - Fat malabsorption syndromes of mineral oil laxatives
54
Vit A- Sx
- Night blindness - Xerosis - Bitot spots
55
Vit A- Dx
- Low serum levels | - Abnormalities in dark adaptation
56
Vit A- Tx
- Oral supplementation
57
Fat
- Unsaturated better - 20-35% of diet - Type of fat important- no trans, saturated