Bugs and Drugs

Question 1

Treatment of choice for adenovirus infections

Answer 1

Cidofovir

Question 2

Drug given with cidofovir to prevent renal tubular uptake (nephrotoxicity)

Answer 2

probenecid

Question 3

Treatment of choice for HSV

Answer 3

acyclovir

Question 4

Treatment of choice for CMV

Answer 4

Gancyclovir

Question 5

Treatment of choice for CMV in patient with pancytopenia

Answer 5

Foscarnet

Question 6

Side effect of gancyclovir

Answer 6

bone marrow suppression

Question 7

Side effect of foscarnet

Answer 7

nephrotoxicity and electrolyte abnormalities

Question 8

Side effect of cidofovir

Answer 8

nephrotoxicity (probenocid helps)

Question 9

side effect of acyclovir

Answer 9

Crystal nephropathy, neurotoxicity

Question 10

Treatment of choice for anthrax

Answer 10

any fluoroquinolone or doxycycline for 60 days

Question 11

Treatment of choice for nocardia

Answer 11

bactrim

Question 12

Treatment of choice for toxoplasmosis

Answer 12

pyrimethamine + sulfadiazine

Question 13

Treatment of choice for strongyloides infections

Answer 13

Daily ivermectin until cleared

Question 14

Tapeworm that causes cysts in the lung and liver

Answer 14

Echinococcus

Question 15

Hookworm that causes nutritional deficits and gets in from direct dermal penetration

Answer 15

Ancyclostoma duodenale

Question 16

Roundworm that causes intestinal obstructions

Answer 16

Ascaris lumbricoides

Question 17

Fluke from raw crab meat that causes eosinophilic pleural effusion

Answer 17

Paragonimus westermani

Question 18

Roundworm that migrates from the GI tract to the lungs and causes bleeding from either organ.

Answer 18

Strongyloides

Question 19

Treatment of choice for hantavirus

Answer 19

supportive

Question 20

Gram negative bacilli beta-Lactamase producing bacteria

Answer 20

ESCHAPPM

Enterobacter
Serratia
Citrobacter
Hafnia
Acinetobacter
Proteus (not mirabilis)
Providencia
Morganella Morganii

Question 21

6 Gram negative bacilli

Answer 21

E coli
ESCHAPPM organisms
Klebsiella
Legionella
Proteus mirabilis
Pseudomonas

Question 22

3 Gram negative cocci/coccobacilli

Answer 22

Neisseria meningitidis
H influ
moraxella

Question 23

2 gram negative anaerobic bacteria

Answer 23

Bacteroides
Fusobacterium

Question 24

3 gram positive anaerobes

Answer 24

Actinomyces
Clostridium
Peptostreptococcus

Question 25

6 gram positive cocci

Answer 25

MRSA MSSA S. Epidermidis Enterococcus Faecium Enterococcus Faecalis Streptococcus

Question 26

5 general gram negative antibiotics

Answer 26

Cefotetan Cefuroxime Ceftriaxone Azithromycin Clarithromcyin

Question 27

10 antipseudomonal abx

Answer 27

Aztreonam Cefepime Ceftazidime Carbapenems (except ertapenem) Colistin Gentamicin Quinolones Polymixin B Tobramicin Zosyn

Question 28

10 MRSA abx

Answer 28

Bactrim Clindamycin Daptomycin Delbavancin Doxycycline (or minocycline) Fosfomycin Gentamycin Linezolid Oritavancin Vancomycin

Question 29

6 MSSA abx

Answer 29

Cefazolin cefalexin Nafcillin Oxacillin Methicillin Dicloxacillin

Question 30

9 abx with anaerobic activity

Answer 30

PCNs Augmentin Cefotetan Zosyn Flagyl Clindamycin Moxifloxacin Doxy/minocycline Carbapenems

Question 31

5 abx for yeast

Answer 31

Micafungin Caspofungin anidulafungin fluconazole posaconazole

Question 32

1 abx for cryptococcus

Answer 32

fluconazole

Question 33

2 abx for histoplasma or blastomycosis

Answer 33

Itraconazole Posaconazole

Question 34

2 abx for aspergillus

Answer 34

Voriconazole Isavuconazole

Question 35

1 abx for mucor

Answer 35

Isavuconazole

Question 36

Organism that causes hypermucoviscous growth on agar plate

Answer 36

Hypervirulent Klebsiella pneumoniae

Question 37

Bacteria found with drinking unpasteurized milk

Answer 37

Brucella

Question 38

Treatment for brucellosis

Answer 38

Doxycycline and either streptomycin or gentamicin

Question 39

Infection in HIV that appears like HLH

Answer 39

Histoplasmosis

Question 40

Drug used to treat severe malaria in the US

Answer 40

Artesunate

Question 41

Drug used to treat mild malaria in the US

Answer 41

Doxycycline