Bugs and their Drugs

Question 1

Enterococcus faecalis Serious Infection

Answer 1

Ampicillin ( or Penicillin G) = Gentamicin or Streptomycin OR Vancomycin = (Gentamicin or Streptomycin), Daptomycin, linezolid, tigecycline

Question 2

Enterococcus faecalis UTI

Answer 2

ampicillin, amoxicillin OR fosfomycin, nitrofurantoin

Question 3

Enterococcus faecium

Answer 3

Linezolid, quinupristin/dalfopristin, daptomycin, tigecycline

Question 4

Staph aureus/epidermidis (MSSA)

Answer 4

Nafcillin or oxacillin, Bacrim, FGC, BL

Question 5

Staph aureus/epidermidis Hospital Aquired (MRSA)

Answer 5

Vancomycin +/- (gentamicin or rifampin) or daptomycin, linezolid, tigecycline, Bacrim, quinuprisin-dalfoprisin

Question 6

Staph aureus/epidermidis Community Aquired (MRSA)

Answer 6

Clindamycin, Bacrim, Doxycycline or Daptomycin, linezolid, telavancin, tigecycline, or vancomycin

Question 7

Streptococcus (Group A,B,C,G, strep bovis)

Answer 7

Penicillin G, Penicillin V, ampicillin or FGC, erythromycin, azithromycin, clarithromycin

Question 8

Streptococcus pneumoniae Penicillin sensitive

Answer 8

Penicillin G, Penicillin V, ampicillin or FGC, doxycycline, azithromycin, clarithromycin, erythromycin

Question 9

Strep pneumoniae Penicillin intermediate

Answer 9

High dose penicillin (12 million units/day for adults), ceftriaxone, cefotaxime

Question 10

Strep pneumoniae Penicillin resistant

Answer 10

Vancomycin +/- rifampin, or per sensitivities: Cefotaxime, ceftriaxone, levofloxacin, moxifloxacin, gemifloxacin

Question 11

Strep viridans

Answer 11

Penicillin G -/+ gentamicin, or, cefotaxime, ceftriaxone, erythromycin, azithromycin, clarythromycin, or vancomycin +/- gentamycin

Question 12

Moraxella Catarrhalis

Answer 12

Amoxicillin-clavulanate, ampicillin-sulbactam, or, erythromycin, azithromycin, clarythromycin, doxycycline, SGC, cefotaxime, ceftriaxone, TGCPO

Question 13

Neisseria gonorrhoeae Disseminated infection

Answer 13

Ceftriaxone or cefotaxime, Follow up: cefpodoxime, ciprofloxacin, levoflocacin

Question 14

Neisseria gonorroeae Uncomplicated infection

Answer 14

Ceftriaxone, Cefotaxime, or cefpodoime

or Ciprofloxacin, levofloxacin

Question 15

Neisseria meningitides

Answer 15

Penicillin G, Cefotaxime, ceftriaxone

Question 16

Clostridium perfringens

Answer 16

Penicillin G +/- clindamycin, or metronidazole, clindamycin, doxycycline, cefazolin, cabapenem

Question 17

Clostridium difficile

Answer 17

Oral metronidazole, oral vancomycin

Question 18

Acinetobacter

Answer 18

Doripenem, inipenem, or meropenem +/- amikacin, ampicillin-sulbactam, colistin, tigecycline

Question 19

Bacteroides fragilis

Answer 19

Metronidazole, BL/BLI, clindamycin, cefoxitin, cefotetan, carbapenem

Question 20

Enterobacter

Answer 20

Carbapenem or cefepime +/- aminoglycoside or ciprofloxacin, levofloxacin, piperacillin - tazobactam, ticarcillin - clavulanate

Question 21

Eschericha coli Meningitis

Answer 21

Cefotaxime, ceftriaxone, meripenem

Question 22

E. coli systemic infection

Answer 22

Cefotaxime, ceftriaxone, BL/BLI, floroquinolone, carbapenem

Question 23

C. coli UTI

Answer 23

Ampicillin, Augmentin, docycycline, cephaleixin, aminoglycoside, FGC, nitrofurantoin, fluoroquinolone

Question 24

Gardnerella vaginalis

Answer 24

Metronidazole, Clinamycin

Question 25

Haemophilus influenzae Meningitis

Answer 25

Cefotaxime or ceftriaxone, meripenem

Question 26

Haemophilius influenzae Other infections

Answer 26

BL/BLI, or if beta lactamase negative, ampicillin or amoxicillin. Bactrim, cefuroxime, azithromycin, clarithromycin, fluorquinolone

Question 27

Klebsiella pneumoniae

Answer 27

BL/BLI, cefotaxime, ceftriaxone, cefepime, carbapenem (Severe), floroquinolone

Question 28

Legionella

Answer 28

Azithromycin, erythromycin +/- rifampin, or florpquinolone, Bacrim, clarithromycin, doxycycline

Question 29

Pasturella Multocidia

Answer 29

Penicillin G, ampicillin, amoxicillin, doxycycline, BL/BLI, Bactrim, cefriaxone

Question 30

Proteus mirabilis

Answer 30

ampicillin, Bacrim

Question 31

Proteus Complex infection

Answer 31

Cefotaxime, ceftriaxone, floroquinolone, BL/BLI, aztreonam, aminoglycoside, carbapenem

Question 32

Providencia stuartii

Answer 32

Amikacin, cefotaxime, ceftriaxone, floroquinolone, bacrim, aztreonam, carbapenem

Question 33

Pseudomonas UTI

Answer 33

Aminoglycoside, Ciprofloxacin, Levofloxacin

Question 34

Pseudomonas Systemic

Answer 34

Cefepime, Ceftazidime, doripenem, imipenem, meropenem, Piperacillin-tazobactam, or ticarcillin-clavulante + aminoglycoside, Azotreonam, ciprofloxacin, levofloxacin, colistin

Question 35

Salmonella typhi

Answer 35

Ciprofloxacin, levofloxacin, ceftriaxone, cefotaxime, Bacrim

Question 36

Serratia marcescens

Answer 36

Ceftriazone, cefotaxime, cefepime, ciprofloxacin, levofloxacin, aztreonam

Question 37

Stenotrophomonas

Answer 37

Bactrim, Sensitives: ceftazidime, doxycycline, minocycline

Question 38

Chlamydia Pneumonia

Answer 38

doxycycline, Azithromycin, clarithromycin, or floroquinolones

Question 39

C. trachomatis

Answer 39

Azithromycin, doxycycline, levofloxacin, erythromcyin

Question 40

Mycoplasma Pneumoniae

Answer 40

Azithromycin, clarithromycin, erythromycin, fluoroquinolone, doxycycline

Question 41

Treponema Pallidum neurosyphilis

Answer 41

Penicillin G, Cetriazone

Question 42

Treponema Pallidum Primary or seconday

Answer 42

Benzathine, penicillin G, Ceftriaxone, doxycycline

Question 43

Borrelia burgdorferi

Answer 43

Ceftriaxone or cefuroxime, doxycline, amoxicillin, high-dose penicillin, cefotaxime