Bugs and Their Drugs

Question 1

Treatment for Staph. aureus infection?

Answer 1

Nafcillin, if MRSA = vancomycin

Question 2

Treatment for Staph. epidermidis infection?

Answer 2

Vancomycin

Question 3

Treatment for Staph. saprophyticus infection?

Answer 3

beta-lactam

Question 4

Treatment for Strep. pyogenes?

Answer 4

Penicillin

Question 5

Treatment for Strep. agalactiae?

Answer 5

Prophylactic peniciliin

Question 6

Treatment for Strep. pneumococcus?

Answer 6

Fluoroquinolones or penicillin (macrolides and ceftriaxone)

Question 7

Treatment for Enterococcus faecalis?

Answer 7

Unasyn + aminoglycoside (genta or strepto)

Question 8

Treatment for Enterococcus faecium?

Answer 8

linezolid or nitrofurantoin

Question 9

Treatment for disseminated Bacillus cereus?

Answer 9

vancomycin, clindamycin, gentamycin, or ciprofloxacin

Question 10

Treatment for Listeria monocytogenes?

Answer 10

ampicillin + gentamycin or Bactrim

Question 11

Treatment for Cornybacterium diphtheria?

Answer 11

Penicillin (1st line) or erythromycin, and horse antitoxin

Question 12

Treatment for nocardia asteroides?

Answer 12

sulfonamides or amikacin + beta-lactam

Question 13

Treatment for Borrelia burgdorferi?

Answer 13

Doxycycline (DOC) or amoxicillin, cefuroxime,erythromycin. take 2-4 times a day for 2-4 weeks

Question 14

Treatment for Borrelia recurrentis?

Answer 14

low doses of beta-lactams (jarisch-herxheimer syndrome)

Question 15

Treatment for Leptospira interrogans?

Answer 15

Doxycycline (DOC), penicillin, or fluoroquinolones

Question 16

Treatment for Rickettsia rickettsii?

Answer 16

Tetracycline (DOC), chloramphenicol, or fluoroquinolones

Question 17

Treatment for Rickettsia prowazekii?

Answer 17

tetracycline and Chloramphenicol for 3-4 days

Question 18

Treatment for Coxiella burnetti?

Answer 18

Tetracycline (DOC), or Bactrim

Question 19

Treatment for Bartonella henselae?

Answer 19

only treat if bacillary angiomatosis or peliosis –> erythromycin or doxycycline

Question 20

Treatment for Pasturella multocida?

Answer 20

beta-lactams

Question 21

Treatment for Bacillus anthracis?

Answer 21

Ciprofloxacin or doxycycline mainly for cutaneous infections

Question 22

Treatment for Yersinia pestis?

Answer 22

Streptomycin or tetracycline

Question 23

Treatment for Francisella tularensis?

Answer 23

streptomycin or gentamycin

Question 24

Treatment for Mycobacterium tuberculosis?

Answer 24

RIPE (rifampin, isoniazid, pyrazinomide, ethambutol) streptomycin all 1st line drugs, 2nd line = linezolid, amikacin, fluoroquinolones, cylcoserine

Question 25

Treatment for Mycobacteria leprae?

Answer 25

rifampin + dapsone + clofazimine

Question 26

Treatment for Neisseria gonorrhoeae?

Answer 26

Ceftriaxone and azithromycin

Question 27

Treatment for Neisseria meningitidis?

Answer 27

Ceftriaxone and penicillin

Question 28

Treatment for Haemophilus influenza?

Answer 28

Ceftriaxone or azithromycin

Question 29

Treatment for Bordatella pertussis?

Answer 29

erythromycin

Question 30

Treatment for Vibrio cholera and parahemolyticus?

Answer 30

electrolytes and fluid and sometimes tetracycline

Question 31

Treatment for Vibrio vulnificus?

Answer 31

tetracycline/doxycycline or fluoroquinolones

Question 32

Treatment for Campylobacter jejuni?

Answer 32

erythromycin or ciprofloxacin

Question 33

Treatment for Helicobacter pylori?

Answer 33

2 abx and 1 PPI (amoxicillin, tetracylcine, metronidazole)

Question 34

Treatment for Legionella pneumophilia?

Answer 34

Macrolides or fluoroquinolones

Question 35

Treatment for Escherichia coli?

Answer 35

when necessary use fluoroquinolones, azithromycin or rifaximin

Question 36

Treatment for Shigella?

Answer 36

Ciprofloxacin or ceftriaxone

Question 37

Treatment for Salmonella?

Answer 37

Ciprofloxacin or ceftriaxone

Question 38

Treatment for Yersinia enterocolitica?

Answer 38

Ciprofloxacine or ceftriaxone or Bactrim

Question 39

Treatment for Klebsiella pneumonia?

Answer 39

polymyxin

Question 40

Treatment for Actinomyces?

Answer 40

debride the wound and beta-lactams

Question 41

Treatment for Propionibacterium acnes?

Answer 41

benzoyl peroxide, retinoic acid, and clindamycin or erythromycin for cystic acne

Question 42

Treatment for Clostridium tetani?

Answer 42

passive immunization w/ toxoid immunoglobulin and vaccine, also debridement and penicillin

Question 43

Treatment for Clostridium botulinum?

Answer 43

passive immunization w/ anti-toxin

Question 44

Treatment for Clostridium perfringens?

Answer 44

debridement and exposure to oxygen for gas gangrene

Question 45

Treatment for Clostridium difficile?

Answer 45

discontinue original antibiotics, fluids and electrolytes, and metronidazole or vancomycin

Question 46

Treatment for Pseudomonas aeruginosa?

Answer 46

Timentin + aminoglycoside, moxifloxacin, or colistin (might treat w/ multiple drugs)

Question 47

Treatment for Burkholderia pseudomallei?

Answer 47

Timentin + aminoglyoside

Question 48

Treatment for Treponema pallidum?

Answer 48

Penicillin or tetracyclines if allergic to penicillin

Question 49

Treatment for Chlamydia?

Answer 49

azithromycin and doxycyline (doxycycline not to be used in pregnant women)

Question 50

Treatment for Mycoplasma?

Answer 50

Azithromycin (1g or Z-pak)