Buzz Words

Question 1

mechanism of action of SSRIs

Answer 1

block reuptake of serotonin into presynaptic cell

Question 2

best SSRI in adolescents

Answer 2

fluoxetine

Question 3

what pathway does fluoxetine block

Answer 3

CYP450

Question 4

best SSRI in epileptics

Answer 4

citalopram

Question 5

safest SSRI in cardiac patients

Answer 5

sertraline

Question 6

contraindicated drugs with SSRIs

Answer 6

triptans
NSAIDS
Aspirin
Warfarin

Question 7

mechanism of action of TCAs

Answer 7

block reuptake of serotonin + noradrenaline into presynaptic terminals

Question 8

mechanism of action of phenelzine

Answer 8

irreversible inhibition of monoamine oxidase enzymes – slows breakdown of noradrenaline + serotonin

Question 9

mechanism of action of moclobemide

Answer 9

reversible inhibition of monoamine oxidase enzymes – slows breakdown of noradrenaline + serotonin

Question 10

what is phentolamine used for

Answer 10

treatment of hypertensive crisis

Question 11

what type of drug is lofepramine and imipramine

Answer 11

TCAs

Question 12

what type of drug is venlafaxine

Answer 12

serotonin noradrenaline reuptake inhibitor

Question 13

mirtazapine

Answer 13

NaSSA

-antagonises adrenergic receptors + blocks serotonin receptors

Question 14

trazodone

Answer 14

given to treat sexual dysfunction caused by SSRI

Question 15

mechanism of action of sodium valproate

Answer 15

increases GABA

Question 16

mechanism of action of lamotrigine

Answer 16

blocks sodium channels - decreases glutamate release

Question 17

typical antipsychotics

Answer 17

haloperidol

chlorpromazine

Question 18

treatment of extra pyramidal side effects

Answer 18

procyclidine

Question 19

mode of action of galantamine + rivastigmine

Answer 19

cholinesterase inhibitors

Question 20

mode of action of memantine

Answer 20

blocks NMDA receptors

Question 21

what is a jaw jerk a sign of

Answer 21

frontal cognitive syndrome

Question 22

confusion, ataxia, ophthalmoplegia

Answer 22

thiamine deficiency

Question 23

which area has strongest association with addiction

Answer 23

septal area

Question 24

problem with broccas area

Answer 24

expressive aphasia

Question 25

problem with wernicke area

Answer 25

receptive aphasia

Question 26

trisomy 18

Answer 26

Edwards syndrome

Question 27

IQ 70-84

Answer 27

Borderline learning disability

Question 28

IQ 50-69

Answer 28

mild learning disability

Question 29

IQ 35-49

Answer 29

moderate learning disability

Question 30

IQ 20-34

Answer 30

severe learning disability

Question 31

IQ <20

Answer 31

profound learning disability

Question 32

PHQ-9 score

Answer 32

used to assess severity of depression

Question 33

SADPERSONs

Answer 33

used to calculate suicide risk

Question 34

oculogyric crisis

Answer 34

example of a dystonic reaction, involuntary prolonged upward deviation of the eyes

Question 35

torticollis

Answer 35

example of a dystonic reaction- asymmetrical head/neck position

Question 36

patient with alcohol dependence 'staggering, confused, restricted eye movements'

Answer 36

wernicke's encephalopathy

Question 37

Korsakoff syndrome

Answer 37

patient acting strange, confabulating, short term memory problems

Question 38

1st line for alcohol dependence relapse prevention

Answer 38

naltrexone

Question 39

mode of action of naltrexone

Answer 39

opioid antagonist - reduces reward from alcohol

Question 40

mode of action of acamprostate

Answer 40

acts of glutamate + GABA systems to decrease cravings

Question 41

mode of action of disulfiram

Answer 41

inhibits acetaldehyde dehydrogenase

Question 42

opioid overdose therapy

Answer 42

naloxone

Question 43

dialectical behavioural therapy

Answer 43

borderline PD

Question 44

Tx of Parkinson's induced psychosis

Answer 44

clozapine

Question 45

Tx of Parkinsons induced dementia

Answer 45

rivastigmine