BY261 - Infection and Immunity Flashcards
Define Immunology
The study of the process initiated by the host when confronted with non-self substances considered dangerous for the body. eg:pathogens
What is the role of the immune system?
To recognise and eliminate dangerous non-self organisms or substances
define Homeostasis
The regulation of internal conditions of a cell or organism to maintain the optimum conditions for function, in response to internal and external changes
the self … non-self concept…
What is an antigen?
Antigens are marker molecules present on the surface of cells, which bind to an antibody or a T-cell receptor hence triggering an immune response.
What is an Epitope?
An epitope (Antigen determinant) is the specific portion of a macromolecular antigen (which is a group of amino acids or other chemical groups exposed on the surface of a molecule) that the antibody or T-cell receptor binds to.
Define the term “immunity”?
Name the 4 types in which innate immunity protects the body.
How long after infection can innate immunity protect the body against a microbe.
Epithelial barrier
Phagocytosis
Phagocytes
NK cells
0-12hrs
Name the 2 types in which adaptive immunity protects the body and the progression in which the cells mature.
best representation is a diagram.
[go back to the maturation of t and b cells in detail… shall mark in text book in green when found]
what is innate immunity?
Innaate immunity is the inbuilt immunity to resist infection.
[build on this from glossary of text]
What is adaptive immunity?
[text]
Name the similarities and the differences of the innate and adaptive immune response
what cells are responsible for both adaptive and innate immunity?
Leucocytes
which cells largely mediate the innate immune response?
granulocytes
which cells mediate the adaptive immune response?
lymphocytes
