c16 & c17 genes to proteins (translation) Flashcards

(29 cards)

1
Q

gene expression

A

is the entire set of processes that results in using the information stored in a gene.
Molecules or events that increase gene expression are said to exert positive control. Molecules and events that decrease gene expression are said to exert negative control.
- Whether or not an RNA gets made from the information encoded in structural sequences. It depends on the events that occur at regulatory sequences

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2
Q

regulatory proteins

A

promoters, transcription factors

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3
Q

promoters

A

promote the gene expression

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4
Q

transcription factors

A

regulate gene expression, usually by binding directly to regulatory sequences in DNA

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5
Q

activators

A
  • Activators are transcription factors that help exert positive control
    Bind to enhancers
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6
Q

repressors

A
  • Repressors are transcription factors that help exert negative control
    Bind to silencers
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7
Q

enhancers

A
  • Enhancers are regulatory sites in DNA that are involved in positive control
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8
Q

silencers

A
  • Silencers are regulatory sites in DNA that are involved in negative control
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9
Q

operon

A

A sequence of structural gene sequences whose products have related functions and that are under the control of the same promoter and other regulatory sequences, meaning that they are transcribed as a unit.

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10
Q

exons

A

expressed, they code for the amino acids found in a protein product/

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11
Q

introns

A

intervene between exons. transcribed but later removed from the mRNA prior to translation

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12
Q

positive control (over gene expression)

A

mechanisms that increase the amount of active gene product available

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13
Q

negative control (over gene expression)

A

mechanisms that decrease the amount of active gene product available

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14
Q

transcription factors

A

proteins that regulate transcription, often by binding to regulatory sequences in DNA

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15
Q

chromatin

A

the complex of DNA and histone proteins that has DNA wrapped around it

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16
Q

nucleosome

A

a group of four histone proteins that has DNA wrapped around it

17
Q

histone proteins

A

proteins that have an abundance of positively charged lysines and arginines in their primary structure, which interact with negative charges on the sugar-phosphate backbone of DNA to form nucleosomes.

18
Q

anticodon

A

a sequence of three bases found at one end of a tRNA that binds to a codon in mRNA during translation via complementary base pairing

19
Q

release factor

A

a protein that fits into the A site of a ribosome, binds to a stop codon, and interacts with the ribosome to terminate translation

20
Q

reading frame

A

the sets of three-base codons in RNA or DNA that specify the primary sequence of codons

21
Q

ribozyme

A

an RNA molecule that catalyzes a chemical reaction, analogous to enzymes, which are protein catalysts

22
Q

genetic code

A

the set of relationships between the 64 possible codons in mRNA and the amino acids that are added to a newly synthesized proteni

23
Q

codon

A

a group of three bases in an mRNA that codes for an amino acids

24
Q

start codon

A

the codon that signals where translation and thus protein synthesis begins. usually AUG and also codes for the amino acid methionine (Met).

25
stop codon
that signals where translation and thus protein synthesis ends. usually UAA, UAG, and UGA
26
endomembrane system
a collection of machines, cytoskeletal componenets and organelles that together produce, process, and transport proteins and lipids destined for organelles, the cell membrane, or outside th ecell
27
signal sequence
a series of amino acids at the start of a protein that allows that protein to enter the endomembrane system
28
motor protein
a protein that fucntion in cell movement through shape changes caused by phosphorylation or dephosphorylation
29
phosphorylation
the addition of a phosphate group (PO4^3) to a protein or other molecule. in most cases, the phosphate group comes from ATP. Dephosphorylation is the reverse process