Calcium Channel Blockers Flashcards
What class of drug is verapamil?
Class IV anti-arrhythmic agent. Calcium channel blocker- phenylalkylamine.
What are some common indications of verapamil?
Arrhythmia, angina and hypertension
What is the mechanism of action of Verapamil?
Inhibits L-type calcium channels. Reduces workload of the heart by reducing force of contraction.
What are the adverse drug reactions of Verapamil?
Constipation, bradycardia, heart block and cardiac failure
What are the drug-drug interactions of Verapamil?
Beta blockers (cardiologist use only) and other antihypertensive and antiarrhythmic agents.
What class of drug is Amlodipine?
Calcium channel blocker- Dihydropyridine.
What are the indications of Amlodipine?
Hypertension and angina
What is the mechanism of action of Amlodipine?
Stops inward displacement of calcium ions. Myocardial contractility and electrical impulses of the heart are reduced. Decrease in vascular tone.
What are the adverse reactions of Amlodipine?
Ankle swelling, flushing, headaches and palpitations
What are some warnings when prescribing Amlodipine?
Unstable angina and severe aortic stenosis
What are some drug-drug interactions of Amlodipine?
Amlodipine and simvastatin
What is significant about Amlodipine?
It has a long half life and others tend to be shorter
How can you remember Amlodopine?
‘Amy’- Amlodipine
CA meron Diaz (Ca 2+ channel blocker)
Symptoms are like that of a pregnant woman, heart palpitations, ankle swelling, headaches and flushing
Adverse reactions- simvastatin, don’t want a pregnant woman to lose weight
How do you remember Verapamil?
Vera- calcium channel blocker
L type. Lonely, lovely Vera
Pearls- white, calcium, white hair
Constipation- common symptom of an elderly person
