cancer

Question 1

acute myelogenous leukemia

Answer 1

occurs in kids and adults

Question 2

acute lymphocytic leukemia

Answer 2

most common type of leukemia in children. can affect adults.

Question 3

chronic myelogenous leukemia

Answer 3

mainly affects adults.

Question 4

chronic lymphocytic leukemia

Answer 4

most often in ppl over age 55

Question 5

inactivates 6MP

Answer 5

TPMT

Question 6

procarbazine

Answer 6

treat Hodgkin’s disease and brain tumors

Question 7

dacarbazine

Answer 7

component of combo therapy for hodgkins lymphoma, also used to treat melanomas and sarcomas

Question 8

temozolomide

Answer 8

used to treat glioblastoma multiforme

Question 9

BEP

Answer 9

bleomycin, etoposide, and cisplatin. used to treat testicular cancer

Question 10

cell cycle specific agents

Answer 10

antimetabolites, topoisomerase inhibitors, antimicrotubule agents, bleomycin

Question 11

cell cycle non-specific agents

Answer 11

doxorubicin and alkylating agents (cyclophosphamide, carmustine, platinum compounds)

Question 12

MOPP

Answer 12

mechlorethamine, oncovin (vincristine), procarbazine, and prednisone. used to treat hodgkins lymphoma.

Question 13

ABVD

Answer 13

Adriamycin (doxorubicin), bleomycin, vinblastine, bacarbazine. used to treat hodgkins lymphoma. works better than MOPP

Question 14

vemurafenib

Answer 14

BRAF inhibitor used to treat melanomas
must have glutamic acid at the 600th position of BRAF rather than valine to use
most pts become resistant

Question 15

ipilimuab

Answer 15

prevents binding of B7 to CTLA4

used to treat melanoma

Question 16

nivolumab

Answer 16

monoclonal ab that binds to PD-1L= prevents it from binding to PD-1
used to treat non-small cell lung cancer, melanoma

Question 17

amifostine

Answer 17

helps reduce nephrotoxicity of cisplatin