Cancer

Question 1

Antifolates drugs

Answer 1

Methotrexate
Raltitrexed
Pemetrexed

Question 2

Pyrimidine analogs

Answer 2

5-fluorouracil
Tegafur 
Capecitabine
Trifluridine
Tipiracil

Question 3

Purine analogs

Answer 3

6-mercaptopurine
6-thioguanine
Fludarabine
Nelarabine

Question 4

Deoxycytidine analogues

Answer 4

Gemcitidine

Cytarabine

Question 5

Inhibition of RNA reductase

Answer 5

Hydroxycarbamide

Hydroxyurea

Question 6

Alkylating agents nitrogen mustard derivatives

Answer 6

Cyclophosphamide
Ifosfamide
Melphalon
Thiotepa

Question 7

Alkylating agents Nitrosurea

Answer 7

Carmustine

Lomustine

Question 8

Alkylting drugs platinium analogs

Answer 8

Cisplatin
Carboplastin
Oxaliplatin

Question 9

Other dna alkylating for glioma

Answer 9

Busulfan
Temozolomide
Dacarbazine
Procarbazine

Question 10

Antibiotics

Answer 10

Bleomycin (in G2 phase)

Actinomycin D

Question 11

Topoisomerase I inhibitors

Answer 11

Irinotecan

Topotecan

Question 12

Topoisomerase II Anthracyclines

Answer 12

Doxorubicin
Daunorubicin
Epirubicin
Idarubicin

Question 13

Topoisomerase II inhibitors Antracenediones

Answer 13

Mitoxantrone

Question 14

Topoisomerase II inhibitors Epidophyllotoxins

Answer 14

Etoposide

Teniposide

Question 15

Taxanes

Answer 15

Paclitaxel
Docetaxel

They inhibit the depolymerization

Question 16

Vinca alkaloids !!! Pediatrics

Answer 16

Vincristine

Vinblastine

Question 17

Others

Answer 17

Estramustine phosphate
Mitotane
Bexarotene

Question 18

Glucocorticoids for cancer

Answer 18

Prednisolone
Methylprednisolone
Dexamethasone

Question 19

Progestins

Answer 19

Medroxyprogesterone

Megestrol

Question 20

Anti estrogen

Answer 20

Tamoxifen
Toremifene
Fulvestrant

Question 21

Aromatase inhibitors

Answer 21

Anastrozole

Exemestane

Question 22

Antiandrogen

Answer 22

Flutamide

Bicalutamide

Question 23

LH-RH analogs

Answer 23

Buserelin
Goserelin
Leuprolide

Question 24

Gn-RH inhibitors

Answer 24

Degarelix

Question 25

Carcinoid tumor drug

Answer 25

Octreotide

Question 26

MTOR inhibitors

Answer 26

Everolimus | Temsirolimus

Question 27

Receptor tyrosine kinase inhibit ABL/Ckit/PDGFR

Answer 27

Imatinib

Question 28

Receptor tyrosine kinase HER2 + EGFR antagonist

Answer 28

Lapatinib

Question 29

Receptor tyrosine kinase EGFR selective antagonist

Answer 29

Afatinib Gefitinib Erlotinib

Question 30

Receptor tyrosine kinase Bruton tyrosine kinase inhibitor

Answer 30

Ibrutinib

Question 31

Receptor tyrosine kinase multiple GFR antagonist

Answer 31

Sorafenib | Sunitinib

Question 32

Receptor tyrosine kinase selective VEGFR 1,2,3 antagonist

Answer 32

Axitinib

Question 33

Multiple tyrosine kinase inhibitors

Answer 33

Regorafenib

Question 34

Receptor tyrosine kinase anaplastic lymphoma kinase inhibitor

Answer 34

Crizotinib | Certinib

Question 35

Receptor tyrosine kinase BRAF kinase inhibitors

Answer 35

Vemurafenib | Dabrafenib

Question 36

Receptor tyrosine kinase MAP kinase inhibitor

Answer 36

Trametinib

Question 37

Proteasome inhibitor

Answer 37

Bortezomib

Question 38

BCL-2 protein inhibitor

Answer 38

Venetoclax

Question 39

Retinoids

Answer 39

Tretinoin Alitretinoin Bexaroten

Question 40

Monoclonal antibody against CD20

Answer 40

Rituximab

Question 41

Anti -EGFR mab

Answer 41

Cetuximab | Panitumumab

Question 42

Anti HER-2

Answer 42

Trastuzumab + emtansin (MT inhibitor)

Question 43

Anti-IL-2

Answer 43

Aldesleukin

Question 44

2 binding sites: CD3 and CD19

Answer 44

Blinatumomab

Question 45

3 binding sites: CD3, macrophages and EpCAM

Answer 45

Catamaxomab

Question 46

Binds CTLA-4

Answer 46

Ipilimumab

Question 47

Binds PD-1

Answer 47

Pembrolizumab

Question 48

Human IgG4 mab which binds PD-1

Answer 48

Nivolumab

Question 49

Anti VEGF-A antibody

Answer 49

Bevacizumab