Cancer and Infection Flashcards

1
Q

What type of cancers does the HPV cause?

A

Cervix, vulva, vagina, penis, anus, mouth or throat.

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2
Q

What does E6 protein expressed by HPV do?

A

Destroys p53.

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3
Q

What does E7 protein expressed by HPV do?

A

Prevents Rb from acting so allows E2F to promote transcription of DNA polymerase.

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4
Q

What type of tumours does EBV cause?

A

Burkitt’s lymphoma, B-cell lymphomas, Hodgkin’s lymphomas, nasopharyngeal carcinomas.

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