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Cáncer epitelial de ovario Flashcards

(13 cards)

1
Q

lugar neoplasias en la mujer

mortalidad ?

A

2º lugar neoplasias en la mujer

mortalidad >50%

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2
Q

FR: hormonales y reproductivos

A

no demostrados
menarca tardía 12 años
menopausia >50 años
endometriosis cel claras

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3
Q

FR: ambientales

A

talco
tabaquismo cancer ep mucinoso
obesidad –> cancer epitelial

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4
Q

FR genéticos

A

HF

H. genéticos: 2 familiares 1er grado RR 50 –> BCRA I,II; Lynch

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5
Q

Factores protectores

A

aquellos que disminuyan los ciclos menstruales por la teoría Fathalla

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6
Q

CLASIFICACIÓN HISTOGÉNETICA DE NEOPLASIAS OVARICAS

A
  • cep epitelio celómico 70%
  • cep germinales –> joven, crecimiento rápido, displasia gonadal
  • cep estroma gonadal –> hormonas
  • mesénquima
  • metastásicos
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7
Q

Clínica

A

1º asintx

-sintx digestivos leves: aumento del perímetro abdominal. dolor abdominal, variación del peso

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8
Q
DX
Gold standar
marcador
-extensión:
-embarazo: 
-seguimiento
-RxTx
A
DX 
Gold standar: US
marcador CA 125
-extensión: TAC
-embarazo: RM
-seguimiento: PET
-RxTx: metástasis pulmonar, derrame pulmonar
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9
Q

Manejo de grupos de alto riesgo

  • ca mama-ovario hereditario:
  • Lynch:
A

Manejo de grupos de alto riesgo

  • ca mama-ovario hereditario: mastografía 25 años, SOB 35-40 o edad más temprana HF
  • Lynch: colonoscopia 25 años, biopsia de endometrio 30 años
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10
Q

PROFILAXIS:

-mutaciones

A

PROFILAXIS: salping-oofectomía

-mutaciones BRCA 1, 2

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11
Q

TAMIZAJE

A

TAMIZAJE

-no existe en población general

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12
Q

PRINCIPALES FORMAS DE DISEMINACIÓN:

-mayor riesgo de recurrencias:

A

PRINCIPALES FORMAS DE DISEMINACIÓN: transcelómica, linfática

-mayor riesgo de recurrencias: transcelómica

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13
Q

TX:

  • QX estadificadora
  • QX citorreducción :
A

TX:

  • QX estadificadora: para estadificar al paciente, histerectomía+ SOB, biopsia correderas, fondo de saco, diafragma
  • QX citorreducción: extirpar tumor dejar <1cm
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