Cancer genetics Flashcards
1
Q
Driver mutations
A
2
Q
Passenger mutations
A
3
Q
Oncogenes
A
4
Q
Tumor suppressor genes
A
4
Q
proto-oncogenes
A
4
Q
Cancer cell definition
A
4
Q
miRNA function
A
4
Q
Excessive-elevated signaling by oncoprotein can lead to
A
- oncogene activation
- DNA damage response
4
Q
Two hit hypothesis
A
5
Q
Monoallelic loss-of-function
A
6
Q
Haploinsufficiency
A
7
Q
methylation of genes
A
8
Q
breakage-fusion-bridge cycles
A
9
Q
chromoplexy
A
10
Q
Chromothripsis
A
