Cancer. Inflammation. Healing. Immunity.

Question 1

What types of cells do become cancerous?

Answer 1

Blood, skin, and liver, bone (parent or progenitor cells)

Question 2

What types do not become cancerous ?

Answer 2

Well-Differenced (skeletal and cardiac muscle)

Question 3

-sacroma and -carcionoma indicate

Answer 3

Malignant tumor

Question 4

Anaplasia

Answer 4

Loss of cellular differentiation

Question 5

Excessive cellular proliferation

Answer 5

Autonomy

Question 6

What must become mutated to become oncogenes?

Answer 6

Protooncogenes

Question 7

Paraneoplastic Syndrome

Answer 7

Tumors release substances that affect neurologic function by mimicking hormones

Question 8

The best way to diagnose cancer?

Answer 8

Biopsy

Question 9

3 purposes of Inflammation?

Answer 9

• neutralize
• limit spread
• prepare repair

Question 10

First responders injury?

Answer 10

Neutrophils

Question 11

Local effects inflammation

Answer 11

Redness, swelling, heat, pain, loss of function

Question 12

Systemic Effects of inflammation

Answer 12

mild fever, malaise, fatigue, headache, anorexia/weight loss

Question 13

Controls of fever (2)

Answer 13

Hypothalamus and pyrogens

Question 14

When does C-Reactive appear in CBC?

Answer 14

With acute inflammation and necrosis

Question 15

ESR

Answer 15

elevated erythrocyte sentiment rate indicates increase rate at which RBC settle

Question 16

Shift to the left

Answer 16

Increase in Bands (= immature neutrophils) indicating BACTERIAL infection

Question 17

Increased lymphocytes indicate

Answer 17

VIRAL infection

Question 18

Leukocytosis indicates

Answer 18

inflammation

Question 19

Resolution healing

Answer 19

minimal tissue damage

Question 20

Regeneration

Answer 20

Damaged tissue replaced by functional tissue

Question 21

Replacement

Answer 21

Functional tissue is replaced by scar tissue

Question 22

Hypertrophic scar tissue

Answer 22

Fibrous tissue with lots of collagen deposits

Ex: keloid formation

Question 23

Ulcerations

Answer 23

Cause further tissue breakdown and impairs blood supply to the area

Question 24

MHC 1

Answer 24

On all nucleated cells to prevent immune cells from destroying self cells

Question 25

MHC 2

Answer 25

On immune cells, antigen-presenting cells, B Cells, and macrophages that have engulfed an antigen

Question 26

IgG

Answer 26

Smallest (can cross placenta)
Main antibody in subsequent response
Antitoxic, antiviral, antibacterial

Question 27

IgM

Answer 27

First in the initial response to an antigen
Large size - stays in the blood
Activates the complement system
Found on B cell surfaces with IgD

Question 28

IgA

Answer 28

Part of the mucous membrane, skin, and first line of defense
Passed through break feeding
Anti-viral and anti-bacterial

Question 29

IgD

Answer 29

On B cell membranes with IgM

Stimulates B cells

Question 30

IgE

Answer 30

Allergies and parasites
Attaches to mast cells and basophils - releases histamine/triggers inflammatory response
Type I hypersensitivity

Question 31

Titre

Answer 31

Measures levels of serum immunoglobulins

Question 32

Indirect Coombs Test

Answer 32

detects Rh in blood (for blood transfusions)

Question 33

Elisa

Answer 33

Detects for HIV antibodies

Question 34

MHC typing

Answer 34

Tissue matching before transplant procedures