Cancer Metastasis Flashcards

1
Q

what main factor affects the opportunity for metastases forming

A

increased blood vessels in the tumour

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2
Q

what are the three modes by which tumour can spread

A

bloodstream, lymphatic system and transcoelemic

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3
Q

the liver is a common metastatic site from what cancer

A

colorectal

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4
Q

axial bone is a common metastatic site from what cancers

A

breast and prostate

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5
Q

the omentum is a common metastatic site from which cancer

A

ovarian

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6
Q

the lung is a common metastatic site

A

true

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7
Q

the spleen is a common metastatic site

A

false

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8
Q

the kidney is not a common metastatic site

A

true

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9
Q

the brain is a common metastatic site

A

true

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10
Q

adrenal glands are not a common metastatic site

A

false

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11
Q

skeletal muscle is a common metastatic site

A

false

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12
Q

the heart is not a common metastatic site

A

true

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13
Q

cachexia is…

A

weight loss associated with cancer

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14
Q

what are local effects of a malignant tumour

A

tissue destruction, bleeding and pain from nerve pressure and perineural infiltration

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15
Q

what are the systemic effects of a malignant tumour?

A

cachexia, normal and abnormal hormone secretion and paraneoplastic syndromes

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16
Q

what are the 4 main types of tumour biomarkers

A

oncofetal proteins, oncogene, growth factors/receptors and immune checkpoint inhibitors

17
Q

what is the key biomarker of hepatocellular carcinoma and testicular teratomas?

A

alpha-feto protein

18
Q

what cancer is Kras a biomarker for!

A

colorectal

19
Q

what cancer is braf a biomarker for?

A

melanoma

20
Q

the biomarkers for lung cancer are…

A

EGFR and PD-L1

21
Q

her2 is a biomarker for…

A

breast cancer