Cancer staging

Question 1

Stage IA ovarian?

Answer 1

One ovary, capsule intact, no tumour on surface, negative washings

Question 2

Stage IB ovarian?

Answer 2

Tumour involves both ovaries, capsule intact, no tumour on surface, negative washings

Question 3

Stage IC1 ovarian?

Answer 3

IA or IB with surgical spill

Question 4

Stage IC2 ovarian?

Answer 4

Either IA or IB but with capsule rupture before surgery or tumour on epithelial surface

Question 5

Stage IC3 ovarian?

Answer 5

Either IA or IB but with malignant cells in the ascites or peritoneal washings

Question 6

Stage IIA ovarian?

Answer 6

Extension and/or implant on uterus and or fallopian tubes

Question 7

Stage IIB ovarian?

Answer 7

Extension to other pelvic intraperitoneal tissues

Question 8

Stage IIIA ovarian?

Answer 8

Positive retroperitoneal lymph nodes and or microscopic mets beyond the pelvis

Question 9

Stage IIIA1 ovarian?

Answer 9

Positive retroperitoneal lymph nodes only
IIIAi: mets <10mm
IIIAii: met >10mm

Question 10

Stage IIIA2 ovarian?

Answer 10

Microscopic, extrapelvic (above the brim) peritoneal involvement +/- positive retroperitoneal lymph nodes

Question 11

Stage IIIB ovarian?

Answer 11

Macroscopic, extrapelvic, peritoneal mets <2cm +/- positive retroperitoneal lymph nodes

Question 12

Stage IIIC ovarian?

Answer 12

Macroscopic, extrapelvic, peritoneal mets >2cm +/- retroperitoneal lymph nodes, includes extension to capsule of liver/spleen

Question 13

Stage IVA ovarian?

Answer 13

Pleural effusion with +ve cytology

Question 14

Stage IVB ovarian?

Answer 14

Hepatic and/or splenic mets, inguinal lymph nodes and lymph nodes outside abdominal cavity

Question 15

Stage IA endo?

Answer 15

<50% of myometrial thickness

Question 16

Stage 1 endometrial 5 year survival?

Answer 16

95%

Question 17

Stage 2 endometrial survival?

Answer 17

77%

Question 18

Stage 3 endometrial survival?

Answer 18

39%

Question 19

Stage 4 endometrial survival?

Answer 19

14%

Question 20

Stage Ib endo?

Answer 20

> 50%

Question 21

Stage 2 endo?

Answer 21

Cervical stroma

Question 22

Stage 3a endo?

Answer 22

Serosa or adenxal invasion

Question 23

Stage 3b endo?

Answer 23

Vaginal or parametrium

Question 24

Stage 3c1 endo?

Answer 24

Pelvic node involvement

Question 25

Stage 3c2 endo?

Answer 25

Para-aortic involvement

Question 26

Stage 4a endo?

Answer 26

Bladder/bowel

Question 27

Stage 4b endo?

Answer 27

Distant mets

Question 28

Treatment low risk stage 1 endo ca?

Answer 28

Total hysterectomy and BSO, careful inspection and/or palpation of the abdomen and pelvis (diaphragm, liver, omentum, pelvic and para-aortic lymph nodes, pelvic and bowel peritoneal surfaces)

Question 29

Low risk endo ca?

Answer 29

Stage 1a endometroid, grade 1-2, LVSI negative

Question 30

Intermediate risk endo ca?

Answer 30

Stage 1b endometroid, grade 1-2, LVSI negative

Question 31

High-intermediate risk endo?

Answer 31

Stage 1b, grade 3

Question 32

High risk endo cancer?

Answer 32

Stage 1 if LVSI +ve Stage ib grade 3 Stage II Stage III

Question 33

``` Adjuvant treatment for endo cancer: Low Intermediate High-intermediate High? ```

Answer 33

Low - none Intermediate - brachytherapy High-intermediate - brachytherapy +/- external beam High - external beam +/- chemo