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BMR 607 Final > Cancer Treatments > Flashcards

Cancer Treatments Flashcards

1
Q

Small Cell Lung Cancer Treatment:

A
  • Chemotherapy is essential
  • Adjuvant chemotherapy is recommended for those who have undergone surgical resection (early stage).
  • Regional metastasis = Radiotherapy/Chemotherapy
  • Extensive metastasis = Just Chemotherapy
  • First Line Chemo: Cisplatin + etoposide
  • Subsequent treatment relapses: Topotectan or docetaxel
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2
Q

Small Cell Lung Cancer Treatment:

First Line Chemo

A

Cisplatin + Etoposide

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3
Q

Small Cell Lung Cancer Treatment:

Subsequent treatment for relapses

A

Topotectan or Docetaxel

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4
Q

Small Cell Lung Cancer Treatment:

Treatment for regional metastasis?

A

Chemotherapy and Radiotherapy

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5
Q

Small Cell Lung Cancer Treatment:

For those who have undergone surgical resection (early stage) what is recommended?

A

Adjuvant chemotherapy.

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6
Q

Non-Small Cell Lung Cancer Treatment:

A
  • Surgery w/ or w/o radiation is the mainstay for localized and regionally advanced tumors.
  • Neoadjuvant and adjuvant therapy: Cisplatin + vinorelbine.
  • Advanced metastatic NSCLCs: Bevacizumab + Platinum compounds
  • First-line therapy in patients with sensitizing EGFR mutations (advanced stages) = Erlotinib
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7
Q

Non-Small Cell Lung Cancer Treatment:

Neoadjuvant and adjuvant therapy

A

Cisplatin + vinorelbine

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8
Q

Non-Small Cell Lung Cancer Treatment:

Mainstay of advanced metastatic NSCLC treatment

A

Bevacizumab + Platinum compounds

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9
Q

Non-Small Cell Lung Cancer Treatment:

What is the recommended first-line therapy in patients with sensitizing EGFR mutations?

A

Erlotinib

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10
Q

Prostate Cancer:

A
  • Radical Prostatectomy (RP) for localized disease
  • RP + RPLND with external beam radiation therapy for regionally advanced disease
  • Androgen deprivation w/ docetaxel for metastatic disease.
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11
Q

Prostate Cancer:

Treatment for localized disease?

A

Radical Prostatectomy (RP)

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12
Q

Prostate Cancer:

Treatment for regionally advanced disease

A

RP + RPLND with external beam radiation therapy.

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13
Q

Prostate Cancer:

Metastatic disease

A

Androgen deprivation with docetaxel

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14
Q

Ovarian Cancer:

A
  • Salpingo-oopherectomy for localized disease
  • Paclitaxel, cisplatin and bevacizumab (I.P.) for advanced cases.
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15
Q

Ovarian Cancer:

Treatment for localized disease?

A

Salpingo-oopherectomy

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16
Q

Ovarian Cancer:

Treatment for advanced cases?

A

Paclitaxel, cisplatin, and bevacizumab (I.P.)

17
Q

Breast Cancer:

A
  • Invasive Breast Cancer:
    • HER2 negative: Doxorubicin & cyclophosphamide followed by paclitaxel
    • HER2 pos: doxorubicin & cyclophosphamide followed by paclitaxel + trastuzumab.
    • Tamoxifen or aromatase inhibitor as adjuvant endocrine therapy (if patient is ER/PR +).
18
Q

Breast Cancer:

What is added to the treatment regimen if it is HER2 Pos?

A

Trastuzumab is added

BMR 607 Final (10 decks)

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