Cancer Treatments Flashcards
(18 cards)
Small Cell Lung Cancer Treatment:
- Chemotherapy is essential
- Adjuvant chemotherapy is recommended for those who have undergone surgical resection (early stage).
- Regional metastasis = Radiotherapy/Chemotherapy
- Extensive metastasis = Just Chemotherapy
- First Line Chemo: Cisplatin + etoposide
- Subsequent treatment relapses: Topotectan or docetaxel
Small Cell Lung Cancer Treatment:
First Line Chemo
Cisplatin + Etoposide
Small Cell Lung Cancer Treatment:
Subsequent treatment for relapses
Topotectan or Docetaxel
Small Cell Lung Cancer Treatment:
Treatment for regional metastasis?
Chemotherapy and Radiotherapy
Small Cell Lung Cancer Treatment:
For those who have undergone surgical resection (early stage) what is recommended?
Adjuvant chemotherapy.
Non-Small Cell Lung Cancer Treatment:
- Surgery w/ or w/o radiation is the mainstay for localized and regionally advanced tumors.
- Neoadjuvant and adjuvant therapy: Cisplatin + vinorelbine.
- Advanced metastatic NSCLCs: Bevacizumab + Platinum compounds
- First-line therapy in patients with sensitizing EGFR mutations (advanced stages) = Erlotinib
Non-Small Cell Lung Cancer Treatment:
Neoadjuvant and adjuvant therapy
Cisplatin + vinorelbine
Non-Small Cell Lung Cancer Treatment:
Mainstay of advanced metastatic NSCLC treatment
Bevacizumab + Platinum compounds
Non-Small Cell Lung Cancer Treatment:
What is the recommended first-line therapy in patients with sensitizing EGFR mutations?
Erlotinib
Prostate Cancer:
- Radical Prostatectomy (RP) for localized disease
- RP + RPLND with external beam radiation therapy for regionally advanced disease
- Androgen deprivation w/ docetaxel for metastatic disease.
Prostate Cancer:
Treatment for localized disease?
Radical Prostatectomy (RP)
Prostate Cancer:
Treatment for regionally advanced disease
RP + RPLND with external beam radiation therapy.
Prostate Cancer:
Metastatic disease
Androgen deprivation with docetaxel
Ovarian Cancer:
- Salpingo-oopherectomy for localized disease
- Paclitaxel, cisplatin and bevacizumab (I.P.) for advanced cases.
Ovarian Cancer:
Treatment for localized disease?
Salpingo-oopherectomy
Ovarian Cancer:
Treatment for advanced cases?
Paclitaxel, cisplatin, and bevacizumab (I.P.)
Breast Cancer:
- Invasive Breast Cancer:
- HER2 negative: Doxorubicin & cyclophosphamide followed by paclitaxel
- HER2 pos: doxorubicin & cyclophosphamide followed by paclitaxel + trastuzumab.
- Tamoxifen or aromatase inhibitor as adjuvant endocrine therapy (if patient is ER/PR +).
Breast Cancer:
What is added to the treatment regimen if it is HER2 Pos?
Trastuzumab is added
