Canine Pathogen Flashcards
Actinomyces
bacterial infection often associated with migration of a grass awn
Acute anterior uveitis
intraocular pressure often decreased below normal (10-20 mmHg), chronic uveitis can lead to glaucoma and resultant high pressures
Ancylostoma caninum
Hookworm; treat with Ivermectin, fenbendazole, pyrantel, or butamisole. Can penetrate through the skin of young pups and migrate to the lungs where they are coughed up and swallowed and mature in the small intestine. There, the worms suck blood and cause bleeding ulcers; up to 0.1 ml of blood per worm can be lost per day. Aberrant migration under the skin of infected people results in cutaneous larva migrans.

Aortic stenosis treatment
Medical management with beta blockers (ex. atenolol) used to reduce myocardial oxygen demand, thus reducing the frequency of ventricular arrhythmias.The owner should also be warned to the dog will need prophylactic antibiotics for any situation in which the dog may develop a bacteremia since it is at high risk of developing infective endocarditis.
Avascular necrosis (Legg-Calves-Perthes Disease)
Results in a collapse or fragmentation of the femoral epiphysis because of a disruption in blood flow. The cause of blood flow interruption is unknown. The condition occurs in young small-breed dogs prior to closure of the capital femoral physis. The condition can be seen bilaterally in 10-17% of patients. Dogs are usually 6-7 months of age when they first start showing clinical signs but the age may range from 3-13 months. Treatment with a femoral head and neck ostectomy (FHO) generally yields excellent results. Alternatively, if owners demand perfect biomechanics, a total hip replacement may be considered, but most veterinarians tend to recommend an FHO.
Blastomycosis
Broad-bases buddy organism. Dog likely has a history of travel to the Ohio River alley.
Blood profile with hypervitaminosis D
High Ca and High P
Excessive intake of vitamin D is associated with an increase in 25-hyroxyvitamin D3 levels. At high levels, 25-hydroxyvitamin D3 competes with 1,25-dihyroxyvitamin D3 for its receptors on the intestines and bone causing increased absorption of Ca and P from te intestinal tract and resorption of bone causing increased levels of circulating Ca and P. A common source of confusion in that this is in contrast to PTH which causes high Ca but generally causes unchanged or normal phosphorus because it also enhances renal phosphorus excretion.
Campylobacteriosis
mucous-laden diarrhea. Gram-negative “gull shaped” rods, single or in pairs or chains.
Canine Distemper
Clinical signs: diarrhea, increased respiratory effort, and seizures. Most susceptible at 3-6 months of age, before 3 months protected by maternally derived antibodies. Very contagious and spreads mainly by aerosolized respiratory secretions. Virus is shed for several weeks after infection.
Diagnosis: Immunofluorescent assay on affected epithelium
canine familial dermatomyositis
Collies
Canine Tracheobronchitis
Caused by canine parainfluenza virus
Central Diabetes Insipidus
Patient has a problem with the function of the hypothalamus (ADH production) and/or neurohypophysis/posterior pituitary (ADH release) so the patient can not respond to the changes in the serum osmolality or blood volume and pressure. The urine specific gravity of a CDI patient is usually 1.001-1.007. The kidneys have no problem responding to ADH in CDI patients. There is a lack of the hormone, not an over-abundance.
Chronic Superficial Keratitis (CSK)
(Pannus or Uberreiter’s disease) immune-mediated inflammatory disease of the cornea, particularly seen in GSDs due to UV light exposure. It is believed that the UV light alters corneal proteins leading to an immune reaction. It is treated with topic steroids and cyclosporine, and animals ofter require lifelong therapy.
Coccidiocomycosis
Spherules - pic in screen shots
Clinical history: chronic cough and development of lameness with lesions over lameness. Chest radiographs - diffuse bronchointerstitial pattern which is nodular in some regions. Hilar lymphadenopathy. Treat with prolonged fungal treatment. Fluconazole is the treatment of choice. Ketoconazole and itraconazole are good choices.
Coonhound paralysis (idopathic polyradiculoneuritis)
may be seen after a raccoon bite, systemic illness, or vaccination; the cause is often unknown. Cranial nerve involvement is usually limited tot he facial and pharyngeal/laryngeal region. Additionally, diffuse hyperesthesia may be present with Coonhound paralysis.
Corneal dermoid
congenital tumour in Dog and Cat
Cricopharyngeal dysphagia
congenital disorder characterized by incoordination of swallow reflex.
Demodex canis
Commensal mite, secondary to an underlying disease or immunosuppression. There are several treatment options. Amitraz (Mitaban) is the only FDA approved one but difficult to get a hold of and use (is a dip and must be administered in a hospital). Ivermectin and milbemycin are also used to treat this condition “off-label” To stop treatment: requires two negative skin scrapes one month apart
Dipetalonema reconditum
is not pathogenic and is therefore not treated.microfilaria parasite found in the peripheral blood of dogs. Blood parasite that looks similar to the microfilariae of Dirofilaria immitis, the agent of Heartworm disease. The two parasites must be differentiated because Dipetalonema reconditum
Dirofilaria immitis
canine heartworm
Dystocia
most common cause is uterine inertia, followed by malpresentation, fetal oversize, narrow canal, and malformation
Eclampsia
Should be suspected in a nursing dog with neurologic signs, pain or stiffness. It is due to reduction in serum-ionized calcium secondary to the demand of producing large amounts of milk. Treatment is with calcium supplementation.
Ehlers-Danlos Syndrome
group of connective tissue disorders that are characterised by fragile, stretchy and loose skin, caused by a genetic defect in the production of collagen
Emphysematous cystitis
Caused by the presence of gas-forming bacteria. Even if a patient is asymptomatic, emphysematous cystitis typically has an underlying cause that should be determined and treated. The most common rule outs include Cushing’s disease (ACTH stimulation test), diabetes mellitus (urinalysis to look for glucosuria), chronic urinary tract infections (urine culture) and bladder stones. Once the underlying disease process is treated, the cystitis will typically resolve with antibiotic therapy.