Canine Viruses

Question 1

rabies virus family

Answer 1

• rhabdoviridae

Question 2

diagnosis gold standard of rabies

Answer 2

• antigen detection (DFA)

Question 3

what is pathognomonic about rabies

Answer 3

• Negri bodies

- not used anymore

Question 4

clinical forms of rabies (2)

Answer 4

• furious

- dumb or paralytic

Question 5

canine distemper family

Answer 5

• paramyxoviridae

Question 6

epidemiology of canine distemper

Answer 6

• high morbidity and mortality

- highly contagious by direct contact (shed in all excretions)

Question 7

forms of canine distemper (5)

Answer 7

• multisystemic
• mild to innapparent
• old dog encephalitis
• hyperkeratosis
• enamel hypoplasia

Question 8

biphasic fever is a clinical sign of ____ that corresponds to onset of ____

Answer 8

• canine distemper

- severe leukopenia

Question 9

two late forms of canine distemper that is usually fatal

Answer 9

• old dog encephalitis

- hard pad disease

Question 10

diagnosis of canine distemper

Answer 10

• antigen detection

Question 11

canine hepatitis family

Answer 11

• adenoviridae - adenovirus 1

Question 12

3 syndromes seen in pups with canine hepatitis

Answer 12

• preacute disease
• acute disease
• mild disease

Question 13

vaccination with CAV-1 vaccine can result in

Answer 13

• bilateral corneal edema (blue eye)

Question 14

vaccination of canine hepatitis

Answer 14

• use CAV-2

- provides herd immunity

Question 15

canine parvovirus family

Answer 15

• parvovirdae

Question 16

3 different age-related disease syndromes of canine parvovirus

Answer 16

• generalized neonatal
• myocarditis syndrome
• leukopenia/enteritis syndrome

Question 17

pathogenesis of canine parvovirus

Answer 17

• enters through oropharynx -> replicates in tonsils and regional lymph nodes
• viremia occurs by day 2

Question 18

canine parvovirus requires host cells to be in ___ phase of cell cycle

Answer 18

• s phase

- replicating

Question 19

diagnosis of canine parvovirus

Answer 19

• SNAP test

Question 20

canine coronavirus family

Answer 20

• Coronarviridae

Question 21

canine coronavirus clinical signs

Answer 21

• mild gastroenteritis

Question 22

canine coronavirus commonly occurs with what virus

Answer 22

• canine parvovirus -> not as good of an outcome

Question 23

vaccine for canine coronavirus

Answer 23

• exists but isn’t used

Question 24

kennel cough is also known as

Answer 24

• infectious canine tracheobronchitis

Question 25

kennel cough is caused by

Answer 25

- diverse group of agents | - why you can still get infected if vaccinated

Question 26

canine influenza family

Answer 26

- orthomyxoviridae (replicates in nucleus!)

Question 27

canine influenza peplomers

Answer 27

- rod-shaped HA | - mushroom shaped NA

Question 28

clinical signs of canine influenza (mild and severe)

Answer 28

- mild - kennel cough - soft moist | - severe - fever, dyspnea, pneumonia

Question 29

why is virus isolation and PCR not useful in diagnosing canine influenza

Answer 29

- need to know what stain you are looking for and it is constantly changing

Question 30

treatment of canine influenza

Answer 30

- symptomatic

Question 31

disinfection of canine influenza

Answer 31

- 1:30 sodium hypochlorite, chlorhexidine, benzalkonium

Question 32

canine parainfluenza family

Answer 32

- paramyxoviridae

Question 33

canine parainfluenza normal clinical signs

Answer 33

- inapparent or mild respiratory disease | - can also cause CNS disease

Question 34

severe cases of canine parainfluenza clinical signs

Answer 34

- conjunctivitis, tonsillitis, anorexia and lethargy

Question 35

virus that can infect humans and jump species

Answer 35

- canine parainfluenza

Question 36

diagnosis of canine parainfluenza

Answer 36

- virus isolation from nose or throat swabs if severe

Question 37

control of canine parainfluenza

Answer 37

- vaccination

Question 38

hemorrhagic disease of pups family

Answer 38

- herpesviridae

Question 39

canine herpes site of entry determines

Answer 39

- clinical signs - nasal cavity -> respiratory disease - mucosal of eye -> eye disease

Question 40

canine herpes transmission

Answer 40

- sexually | - can cross placenta and infect puppies during birth

Question 41

can canine herpes cause abortion

Answer 41

- yes

Question 42

when canine herpes is an problem during reproduction

Answer 42

- if infection is at time of pregnancy or right before having the litter

Question 43

canine herpes in puppies is severe because of ____ that enables the virus to spread

Answer 43

- having a low body temperature

Question 44

clinical signs of canine herpes in puppies

Answer 44

- crying weakness, depression - discharge from nose - soft, yellow feces - loss of suckling reflex

Question 45

reactivation of canine herpes can be caused by what (2)

Answer 45

- stress | - immunosuppressive drugs (steroids)

Question 46

diagnosis of canine herpes in puppies upon necropsy

Answer 46

- hemorrhages in kidneys, liver, lungs and GI tract

Question 47

what does serology show in respect to canine herpes

Answer 47

- what dogs have been exposed

Question 48

canine papillomatosis family

Answer 48

- papovaviridae

Question 49

lesions of canine papillomatosis

Answer 49

- in cutaneous and mucous membranes | - look dry (cauliflower like)

Question 50

clinical signs of young animals with canine papillomatosis

Answer 50

- oral - ocular - genital

Question 51

clinical signs of all ages with canine papillomatosis

Answer 51

- cutaneous

Question 52

treatment of canine papillomatosis

Answer 52

- no treatment | - usually regresses in months but can take up to 2 years

Question 53

diagnosis of canine papillomatosis

Answer 53

- immunohistochemistry can idnetify virus within lesion

Question 54

control of canine papillomatosis

Answer 54

- separate affected animals in groups settings

Question 55

best way to control canine herpes

Answer 55

- keep negatives away from positives