Canterbury Presentation

Question 1

Flucticasone Propionate can be used in?

Answer 1

4 y/o +

Question 2

Flutciasone furuoate can be used in?

Answer 2

2 y/o +

Question 3

1st gen antihistamines can cross and cause what?
2nd gen anthistamines can cross and cause what?

Answer 3

1st gen - BBB and sedation - used with caution
2nd gen - NO CROSSING - does not cause sedation

Question 4

Use anthistamines as what prior to exercising?

Answer 4

Prophylaxis

Question 5

Azelastine age restrictions for prescribing?

Answer 5

5-11 y/o half dose; 12+ full dose

Question 6

How long should you use sympathomimetics for?

Answer 6

3-5 days ONLY; can cause serious adverse effects if used longer such as rebound sutffiness, CV events, stroke, death.

Question 7

Antihistamines can cause what kind of reaction in the elderly?

Answer 7

Glaucoma and BPH

Question 8

Best antitussive agent?

Answer 8

Dextamethorphan

Question 9

What should you avoid in the common cold?

Answer 9

Abx, it will go away

Question 10

When should you avoid OTC pediatric cold meds?

Answer 10

< 6 y/o

Question 11

Purpose of Asthma medication usage?

Answer 11

DECREASE impairment and DECREASE risk

Question 12

COPD diagnosis regarding FEV1/FVC?

Answer 12

<0.70 (this claims there is some form of obsturction

You want > 0.75 in older adults and >0.85 in young adults and adolescents

Question 13

Initial tx/order of asthma: I Like Lazy Saturdays

Answer 13

ICS
Leukotreine mods
LABA
SABA

Question 14

Goal of asthma therapy: SABAs and ICS

Answer 14

ICS as PRN
uses SABAs as PRN and sparingly

USE TOGETHER

Question 15

1 controller of asthma?

Answer 15

ICS (budesonide and fluticasone)

Question 16

A/e of ICS for use of asthma? HOCUS pocus

Answer 16

Hoarseness
oral thrush
coughing
URI
sor throat

Question 17

Leukotriene mod MAJOR adverse effect? BLACK BOX?

Answer 17

neuropsychiatric effects such as insomnia, depression, night terrors, anxiety

Question 18

BIG 3 uses of Montelukast?

Answer 18

asthma prophylaxis 1 y/o+
decreasing exercise bronchospasm in 15 y/o+
relief of allergic rhinitis

Question 19

When would you use cromolyn (MCS)?

Answer 19

prior to an asthma attack!!! NEVER GIVE DURING!!!!! Will not affect it

Question 20

Omalizumab should have what lab drawn prior?

Answer 20

needs antibody test prior to use to identify antibody presence of IgE

Question 21

What medication should be paired with a LABA to decrease mortality? Why?

Answer 21

ICS d/t ICS managing inflammation, LABAs do not decrease inflammation only bronchodilate

Question 22

Theophylline needs what life style modification? Why?

Answer 22

Smoking cessation d/t smoking accelerating metabolism…. the medication will have no affect if the medication is rapidly metabolized.

Question 23

Ipratopium can only be used for what?

Answer 23

COPD ONLY, can be used off label for asthma

Question 24

Ipratopium can worsen?

Answer 24

Glaucoma…

Question 25

Aclidium is what class of med? What is it contraindicated in?

Answer 25

LAMA; patients with glaucoma and urinary retention..... can further worsen both

Question 26

Bacteriostatic vs. Bactericidal?

Answer 26

static - decreases protein synthesis (decrease replication -- "static") cidal - kills

Question 27

What major bacteria does tetracycline target?

Answer 27

Mycoplasma

Question 28

Clindamycin can cause what? What do you do if this occurs?

Answer 28

C. diff, stop and initiate vancomycin

Question 29

Macrolides can cause what?

Answer 29

Widening QT interval

Question 30

Linezolid is used for?

Answer 30

Untreatable infx such as MRSA, VRE, etc.

Question 31

Most aminoglycosides are what? static or cidal?

Answer 31

CIDAL!

Question 32

What happens if you increase aminoglyocisde dose?

Answer 32

Increase clearance of infx

Question 33

What do you monitor for in regards to gentamicin?

Answer 33

RENAL and OTOTOXICITY d/t narrow index

Question 34

How do you monitor for chronic gentmicin use?

Answer 34

Trough and peak GATHER TROUGH prior to admin to assess narrow index

Question 35

What can cause gentamicin otoxicity and nephrotoxicity?

Answer 35

High gentamicin troughs

Question 36

Tobramycin and Aztreonam use?

Answer 36

Nebulization for P. aerugonia Increase concatenation in the airways; decrease systemic concentration = increase safety

Question 37

What two things are trimethoprim is used for? Trimethoprim/Sulfamethoxazate is ued for?

Answer 37

Travelers diarrhea, middle ear inf Pneumostatic pneumonia (PCP)

Question 38

You should not use a sulfonamide in what age group?

Answer 38

< 2 mos r/t kernicterus

Question 39

When is an individual clear of TB?

Answer 39

Sputum is clear of mycobacterium r/t tx -- still take medications post sputum clearance to avoid recurrence and resistance

Question 40

Isnoiazid (INH) is used as what?

Answer 40

single tx of active TB prophylaxis for TB

Question 41

Primary tx of active TB?

Answer 41

Rifampin and INH

Question 41

Rifampin can cause what in a patient?

Answer 41

red/orange excretions

Question 42

What is the biggest issue for INH?

Answer 42

Resistance

Question 43

What should you monitor for a pt on INH?

Answer 43

LFTs every 2 weeks

Question 44

Rifampin can do what if not trying to get pregnant?

Answer 44

decrease contraception abilities

Question 45

What should you monitor for pts on rifampin?

Answer 45

LFTs

Question 46

Ethambutol is contraindicated in what pt population?

Answer 46

NOT RECOMMENDED FOR CHILDREN

Question 47

Ethambutol can cause what?

Answer 47

Optic neuritis - can cause distortion of colors

Question 48

Amphotericin B can cause what?

Answer 48

ALWAYS CAUSE renal toxicity, will improve once off

Question 49

What should you monitor with a patient on amphotericin B?

Answer 49

Renal fx test q 3-4 days

Question 50

What antifungal should a woman not take?

Answer 50

Ketoconazole d/t hepatotoxicity

Question 51

What fluoroquinolone can you use for kids >28 days?

Answer 51

Levofloxacin

Question 52

What fluoroquinoline can you NOT use for kids < 16 y/o?

Answer 52

Ciprofloxacin