CAP BOARDS 2 Flashcards

(627 cards)

1
Q

Beta-2 agents and mixed beta-1/beta-2 agents (non selective) such as propranolol will induce what in asthmatic patients?

A

bronchospasm

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2
Q

Sexual orientation may be a more stable trait in males or females?

A

males

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3
Q

Most common inherited cause of ID in males?

A

Fragile X

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4
Q

what are early signs of autism? (4)

A

1) absence of social smile by 6 mo of age
2) not babbling or pointing by 12 mo
3) not using single words by 16 mo
4) unable to use 2-word phrases

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5
Q

Results of the TEOSS (Early Onset Schizophrenia Spectrum Disorders Study)?

A

< 50% of patients responded over 8 wks of tx
All tx arms were equally efficacious (risperidone, olanzapine, and molindone)
There were no differences in EPS in the tx arms, but this result was likely influences by the ppx use of cogentin in the molindone group

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6
Q

The neurotransmitter principally affected by fluvoxamine is produced in what brain region?

A

Raphe nuclei (serotonin)

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7
Q

Norepinephrine is produced where?

A

Locus coeruleus

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8
Q

What neurotransmitter is produced in the locus coeruleus?

A

Norepinephrine

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9
Q

What neurotransmitter is produced in the raphe nuclei?

A

Serotonin

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10
Q

Where is serotonin produced?

A

Raphe nuclei

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11
Q

Ach is produced where?

A

Nucleus basalis of Meynert

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12
Q

What is produced in the nucleus basalis of Meynert?

A

Ach

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13
Q

Where is histamine produced?

A

Tuberomammillary nucleus

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14
Q

What is produced in the tuberomammillary nucleus?

A

Histamine

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15
Q

Where is dopamine produced? (2)

A

Substantia nigra and VTA

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16
Q

What neurotransmitter is produced in the substantia nigra and the VTA?

A

Dopamine

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17
Q

Risperidone has FDA approval for agitation in autism - age range?

A

5-16

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18
Q

Risperidone has FDA approval for the tx of schizophrenia - age range?

A

13-17

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19
Q

Risperidone has FDA approval for the tx of bipolar d/o - age range?

A

10-17

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20
Q

The ionic gradient necessary for a neuron to generate action potentials is established the distribution of what three ions and how?

A

K+, Cl-, Na+

High concentrations of Na+ and Cl- outside the cell membrane and high concentrations of K+ inside the cell membrane

At rest, K+ and Cl- channels are open so that K+ and Cl- gradients determine the membrane’s resting potential, which is negative by about -50mV to -75mV. Once depolarized beyond the cell’s threshold potential, voltage-gated Na+ channels open rapidly, depolarizing the membrane. The membrane potential shifts to +50mV quickly.

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21
Q

16 month child is sitting with his mother in a room, then walks over to the doorway. he walks just outside the door, looks back at his mother, and begins to cry. It seems as if he wants to explore the next room but is uncertain about leaving his mother. According to Mahler, this child is most likely in which developmental sub-phase?

A

Rapprochement (15-24 months).

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22
Q

According to Mahler, when does hatching occur?

A

5-9 months. The infant becomes aware that he/she is separate from the mother, notices surroundings, but still uses the mother as the primary reference point for understanding the world.

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23
Q

According to Mahler, when does practicing occur?

A

9-16 months, the infant can physically move about alone

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24
Q

MMPI-A can be used in what age range?

A

14-18.

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25
If a patient is already taking valproate, what is the ideal lamotrigine dose?
Initial dose should be divided to half of the normal dose then increased to a therapeutic dose gradually.
26
According to the AACAP Practice Parameters for Cultural Competence, it is more common for minority children and adolescents to engage in mental health care after referral from the court or school for disruptive bx. TRUE or FALSE?
TRUE
27
According to the AACAP Practice Parameters for Cultural Competence, non-hispanic white families are ?x more likely to seek mental health care for their children compared to minority families?
2x
28
School administrators want to create a behavioral intervention plan for an aggressive student. What is the first major step in creating this plan?
Functional behavioral analysis (FBA) - systematic method for describing a problem behavior and identifying "antecedent and consequent events" that cause or contribute to the bx.
29
Abilify is approved to tx irritability in kids with autism - what age range?
6-17
30
a 16M discusses sexual fantasies towards an older cousin during the course of psychotherapy. Which principal justifies leaving out a more descriptive account of the adolescent's sexual fantasy?
Nonmaleficience, do not harm. It includes not causing physical pain or emotional suffering or depriving others of beneficial things.
31
A recent study found that children with which gene's variant allele were more likely to become violent and antisocial adults following child abuse?
MAO-A
32
According to the Treatment of SSRI-resistant Depression in Adolescents (TORDIA) trial, after failing a trial of an SSRI, what is the next step?
SSRI or venlafaxine, but venlafacine had more side effects (so the answer is SSRI :)
33
What group did the Treatment of SSRI-resistant Depression in Adolescents (TORDIA) trial look at?
adolescents that had not responded to a previous 2-month course of an SSRI
34
What medications were looked at in the Treatment of SSRI-resistant Depression in Adolescents (TORDIA) trial? (4)
Paroxetine, citalopram, fluoxetine, and venlafaxine
35
In the Treatment of SSRI-resistant Depression in Adolescents (TORDIA) trial, patient who switched to another medication and added CBT had a response rate of?
55% (in comparison to 41% who did not add CBT)
36
In the Treatment of SSRI-resistant Depression in Adolescents (TORDIA) trial, those who switched to another medication (and did not add CBT) had a response rate of?
41% (in comparison to 55% w CBT)
37
Did the Treatment of SSRI-resistant Depression in Adolescents (TORDIA) trial exclude patients who endorsed SI?
No.
38
The Treatment of SSRI-resistant Depression in Adolescents (TORDIA) trial did not exclude patients who endorsed SI. Did the medications reduce SI?
No
39
In the Treatment of SSRI-resistant Depression in Adolescents (TORDIA) trial, what side effects were seen with venlafaxine?
Skin infections and cardiovascular side effects
40
In the Treatment of SSRI-resistant Depression in Adolescents (TORDIA) trial adolescents with a history of what four things were less likely to respond to tx? (4)
1) Chronic depression 2) Severe hopelessness 3) Self-harm bx 4) Family conflict
41
A 12 month old child has begun to walk and moves around the room, still preferring close contact with the mother at all times. According to Mahler, this child is most likely in which developmental sub-phase?
Practicing (9-16 months). The infant can physically move about alone.
42
What protocol is used for therapy tx with adolescents experiencing PTSD and concurrent substance use?
Seeking safety
43
17M is brought to the hospital for hallucinations and bizarre bx. He is screaming that his abdomen hurts. The nurses report that his urine has an unusual color. Dx?
Acute intermittent porphyria
44
Psychosis + abdominal pain + purple urine. Dx?
Acute intermittent porphyria
45
3 sxs of Acute intermittent porphyria?
Psychosis + abdominal pain + purple urine
46
What is Acute intermittent porphyria?
Rare autosomal dominant disease that affects heme production resulting from a deficiency of the porphobilinogen deaminase. The exact mechanism of acute attacks not clear. The most favored hypothesis is that porpholobilinogen buildup causes a toxic effects on neurons.
47
What cell types produces myelin in the CNS?
Oligodendrocytes. They are also a type of glial cell.
48
Macroglia are divided into what 5 types?
1) astrocytes 2) oligodendrocytes 3) ependymal cells 4) radial glia 5) Schwann cells
49
Astrocytes are a type of macroglia - function?
Form biochemical support of endothelial cells that form the blood-brain-barrier, provide nutrients to CNS, maintain ion balance, and play a role in the repair and scarring process of the brain and spinal cord
50
Oligodendrocytes are a type of macroglia - function?
Insulate axons in the CNS by providing myelin sheath
51
Ependymal cells are a type of macroglia - function?
Line the ventricles and are part of CSF production
52
Radial glia are a type of macroglia - function?
Primary progenitors capable of becoming neurons, astrocytes, and oligodendrocytes that also serve as a scaffold upon which newborn neurons migrate
53
Schwann cells are a type of macroglia - function?
Myelinate nerves in the PNS (oligodendrocytes are in the CNS)
54
Nonfunctional or reduced function alleles occur in approx 25-30% of Caucasians, resulting in about what percentage of the population having the phenotype associated with abnl metabolism? (CYP2D6)
5-10%
55
Atomoxetine is affected by which CYP?
2D6
56
When is the best time to measure plasma levels of lithium during therapy?
12 hours after the last dose
57
Which law in the US sets forth the basic requirements for an IEP?
Individuals with Disabilities Education Act
58
The Higher Education Act of 1965 was intended for what?
To strengthen the educational resources of our colleges and universities and to provide financial assistance for students in post-secondary and higher education. It increased federal money given to universities, created scholarships, gave low-interest loans for students, and established a National Teachers Corps
59
Section 504 is part of what Act?
Rehabilitation Act of 1973 that prohibits discrimination based upon disability. Section 504 is an anti-discrimination civil rights statute that requires the needs of students with disabilities to be met as adequately as the needs of the non-disabled are met.
60
What percent of patients with autism have Fragile X?
3-5%
61
What is the most common genetic cause of ID in boys?
Fragile X
62
What is the most common genetic cause of ID?
Down syndrome
63
What is imprinting?
A gene is silenced or otherwise altered by one parent, which can influence the offspring (Prader-Willi or Angelman)
64
What is anticipation?
Genetic syndrome that appears to become more pronounced with successive generations. (Fragile X)
65
Example of anticipation?
Fragile X. Genetic syndrome that appears to become more pronounced with successive generations.
66
Method of training by which successive approximations toward a target bx are reinforced
Shaping
67
Learning process in which an innate response to a potent stimulus comes to be elicited in response to a previously neutral stimulus
Classical conditioning
68
Type of learning in which the strength of a bx is modified by its consequences, such as reward or punishment
Operant conditioning
69
Walks, puts a block in a cup, drinks from a cup, and says "mama" and "dada" specifically - age?
1 year
70
17M w reddened conjunctivae, speaking in hushed tones and has tachycardia and a dry mouth. The patient's parents are worried about his grades at school, but he says he has "got it all figured out." Which drug is responsible for his sxs?
Cannabis | also causes paranoia and a slowed sense of time
71
Vertical nystagmus is pathognomonic for what?
PCP intoxication
72
Paranoia, hallucinations, aggression, and vertical nystagmus - drug?
PCP
73
HTN, anxiety, and diaphoresis - drug intoxication?
Cocaine
74
MRI shows large tumors on both VIII cranial nerves. Which syndrome is this child most likely to have?
NF2 (acostic neuromas)
75
MRI shows large tumors on both VIII cranial nerves. Which syndrome is this child most likely to have? inheritance patterN?
NF2 (acostic neuromas) | Autosomal dominant
76
Large spots on the skin (cafe-au-lait-spots), optic gliomas, pigmented raised spots on the iris. Which syndrome is this child most likely to have?
NF1
77
Large spots on the skin (cafe-au-lait-spots), optic gliomas, pigmented raised spots on the iris. Which syndrome is this child most likely to have? Inheritance pattern?
NF1 | Autosomal dominant
78
What concept was developed by Bowlby?
Attachment theory
79
Multisystemic therapy (MST) is used for what dx?
Conduct disorder MST is an intensive family and community-based tx for serious juvenile offenders with possible substance abuse issues and their families. The
80
What are the primary goals of MST?
Decrease youth criminal bx and out-of-home placements. Indicated for kids w conduct disorder
81
Testing for Fragile X syndrome involves what method?
PCR (# of CGG repeats) followed by Southern Blot (used to distinguish large pre-mutations from full mutations and to measure the degree of methylation of the FMR1 gene
82
A young child is evaluated for ID. His parents note that he frequently attempts to bit and scratch himself, often leaving serious woulds on his arms. They recall having an abnormal genetics evaluation. At that time, they were advised to feed him a special diet. Dx?
Lesch-Nyhan disease Caused by a mutation on the X chromosome. It causes a build up of uric acid in the body. It can partially be compensated for with a diet limiting the uric acid production
83
A young child is evaluated for ID. His parents note that he frequently attempts to bit and scratch himself, often leaving serious woulds on his arms. They recall having an abnormal genetics evaluation. At that time, they were advised to feed him a special diet. Caused by a mutation on what?
Lesch-Nyhan disease Caused by a mutation in the HGPRT gene located on the X chromosome. It causes a build up of uric acid in the body due to the HGPRT deficiency. It can partially be compensated for with a diet limiting the uric acid production
84
A young child is evaluated for ID. His parents note that he frequently attempts to bit and scratch himself, often leaving serious woulds on his arms. They recall having an abnormal genetics evaluation. At that time, they were advised to feed him a special diet. Causes what?
Lesch-Nyhan disease Caused by a mutation on the X chromosome. It causes a build up of uric acid in the body. It can partially be compensated for with a diet limiting the uric acid production
85
A former patient's father has difficulty paying off their bill and offers his construction services (he is a contractor). In what situation would this exchange be considered ethical?
As long as the work is at fair market value
86
A 16M 2nd generation Mexican American is brought by his parents under court order for a psychiatric evaluation stemming from gang involvement. The patient reports that his grandparents were just "stupid farmers" and "did not understand the world." He also remarks that "Americans just care about money, and we (the gang) actually care about each other." Define.
Negative identification: form of marginalization where the youth is openly hostile towards both cultures and may adopt gang culture.
87
Represented by rejection of the host culture and remaining bound to an "ethnic enclave."
Separation
88
Involves a separation from both cultures and some degree of ethnic identity diffusion.
Marginalization
89
What value tells how likely the result of a study was due to random chance?
P value
90
What does P = 0.01 mean?
That there is a 1 in 100 probability that the positive results of the study were due to chance, rather than due to a real effect of the drug
91
What is absolute risk reduction and how is it calculated?
The difference between the risk of an outcome in the exposed group and the unexposed group. Mathematic inverse of NNT = control event rate - experimental event rate NNT = 1 / (control event rate - experimental event rate)
92
A well-designed randomised controlled trial in children with a particular disease found that 20 per cent of the control group developed bad outcomes, compared with only 12 per cent of those receiving treatment. ARR?
20%-12% = 8% If 100 children were treated, 8 would be prevented from developing bad outcomes. NNT = 100/8 = ~13. The NNT for one child to benefit is about 13.
93
A well-designed randomised controlled trial in children with a particular disease found that 20 per cent of the control group developed bad outcomes, compared with only 12 per cent of those receiving treatment. ARR?
20%-12% = 8% If 100 children were treated, 8 would be prevented from developing bad outcomes. NNT = 100/8 = ~13. The NNT for one child to benefit is about 13.
94
A well-designed randomised controlled trial in children with a particular disease found that 20 per cent of the control group developed bad outcomes, compared with only 12 per cent of those receiving treatment. NNT?
20%-12% = 8% = ARR If 100 children were treated, 8 would be prevented from developing bad outcomes. NNT = 100/8 = ~13. The NNT for one child to benefit is about 13.
95
What is the leading known cause of ID?
Fetal alcohol syndrome
96
What is a potential side effect of atomoxetine that affects males only?
Priapism.
97
What % of study subjects with ADHD responded preferentially to 1 of 2 classes of stimulants (methylphenidate vs amphetamine)?
44%
98
What is the initial response rate to stimulants if both stimulant classes are tried (methylphenidate and amphetamine)?
85%
99
A 16M suffering from acute mania and psychosis presents to the ED. The patient is agitated and demands to leave. The psychiatrist gives IM Haldol. Which ethical principal is working here?
Beneficience
100
Runs, stacks 4 blocks, removes garments, says at least 6 words. Age?
18 months
101
What is the correct sequence of infant development as described by Margaret Mahler? (3)
1) Autistic phase (1st few weeks of life) 2) Symbiotic phase (until 5 months of age, recognizes mother but lacks a sense of individuality) 3) Separation-individuation phase - hatching (increased interest in the outside world) - practicing (9-16 months, developing the physical ability to separate from mother) - rapproachement (15-24 months, exploring the outside world but needing mother to be present and offer support)
102
A child is noted to believe in strict rules and is unable to appreciate any exceptions or nuances to rules, such as the mindset of the person or the situation which the person was facing that the time. Which stage of cognitive development is the child most likely at?
Preoperational (concrete in their thinking, will often adopt a rigid belief in rules, and will fail to understand exceptions or motives behind possibly needing to break the rules. Age 2-7
103
A child is noted to believe in strict rules and is unable to appreciate any exceptions or nuances to rules, such as the mindset of the person or the situation which the person was facing that the time. Age?
Preoperational (concrete in their thinking, will often adopt a rigid belief in rules, and will fail to understand exceptions or motives behind possibly needing to break the rules. Age 2-7
104
9M is treated for depression. He is American born, but his family is originally from Ecuador. He is generally a good student, but this year his grades have suffered. His mother has a h/o depression that reportedly has responded well to tx with fluoxetine. Of note, the patient is a poor metabolized of fluoxetine. What is the primary consideration when dosing fluoxetine for this boy?
size. Dosing medication in older children and adolescents mainly relies on differences in body size between child and adults. Fluoxetine is FDA approved for the treatment of depression in children 8 years old +.
105
Approx what percentage of patients with chronic alcohol use disorders have at least one parents with chronic alcohol use disorder?
30%
106
16M expresses resentment towards having to care for his younger child. When he is w his friends, he consistently reports how wonderful it is to be a father. At times, he worries about his capabilities and is concerned that he will not be able to provide for his child. Defense mechanism?
Reaction formation: conversion of unconscious wishes into their opposites. The bx is the opposite of what one really desires or feels.
107
The unconscious modeling of one's self after another person's character and bx
Identification
108
Ensures that what is unacceptable to the conscious mind, and would if recalled arouse anxiety, is prevented from entering into it.
Repression
109
Shift of a sexual or aggressive drive to a more acceptable target The mind substitutes either a new aim or a new object for goals felt in their original form to be dangerous or unacceptable.
Displacement
110
Separation of a cognitive process from the affect that is associated with it
Isolation of affect
111
Wilson's disease - inheritance pattern?
autosomal recessive
112
A family h/o sleepwalking or sleep terrors is reported in up to what percentage of patients with sleepwalking disorder?
80%
113
Severe side effects of ecstasy abuse and intoxication? (7)
1) Coagulopathy 2) Acute renal failure 3) Hepatotoxicity 4) Rhabdomyolysis 5) Death 6) convulsions 7) body temp dysregulations
114
Common side effects of MDMA?
1) PMR 2) increased sexual response 3) bruxism 4) trismus 5) anorexia 6) sweating
115
A group of 3.5 y/o children are playing in a sandbox with the same toys. What kind of play behavior are they most likely to exhibit?
Associative play: (around 3 years old) Individual play starts to overlap. They share the same toys but will still play separately
116
What type of play is commonly seen with 4 y/os.
Cooperative play. Children play with toys and interact with each other.
117
At what age do you commonly see parallel play?
2 y/o
118
Parallel, associative, and cooperative play are the progressive stages of play during what Piaget development period?
Preoperational (preschool age)
119
Rash w facial involvement, mucus membrane involvement, fever, and lymphadenopathy after lamotrigine is a sign of what?
SJS
120
Lamotrigine overdose can be fatal. The most common sxs include stupor, convulsions, and intraventricular delay. Tx?
Supportive
121
A cohort study was designed to examine the Development of MDD in children of divorced parents vs married parents. What measure should the researchers use to express the probability of an event occurring when comparing an exposed group to a non-exposed group.
Relative risk. Expresses the probability of an event occurring when comparing an exposed and a non-exposed group (incidence of exposed over incidence of unexposed). It is used in RCT and cohort studies.
122
Used to calculate risk in a case-control study and signifies the odds of having a disease given an exposure (odds of disease with exposure over odds of disease without exposure).
Odds ratio.
123
For rare diseases, the odds ratio approximates what?
Relative risk
124
Calculated as the # of events over the number of subjects. It is used to calculate several measures, including relative risk and absolute risk reduction.
Event rate
125
Similar to relative risk (expresses the probability of an event occurring when comparing an exposed and non-exposed group), but while relative risk ratios are cumulative over the course of a study, this ratio reflects the instantaneous risk over a specific time period. It is helpful when 2 groups are experiencing events at different rates, even if the overall event rate may be similar.
Hazard ratio
126
17F c/o recent episodes of extreme anxiety, racing pulse, and cold sweats. Her urine vanillyl mandelic acid is elevated. What neurotransmitter is produced in excess?
Norepinephrine | pheochromocytoma
127
17F c/o recent episodes of extreme anxiety, racing pulse, and cold sweats. Her urine vanillyl mandelic acid is elevated. A neurotransmitter is produced in excess - where is it produced?
Norepinephrine - pheochromocytoma
128
17F c/o recent episodes of extreme anxiety, racing pulse, and cold sweats. Her urine vanillyl mandelic acid is elevated. Dx?
pheochromocytoma
129
17F c/o recent episodes of extreme anxiety, racing pulse, and cold sweats. Her urine vanillyl mandelic acid is elevated. Where might you see a mass?
pheochromocytoma -- usually see an adrenal mass
130
In structural family therapy, the therapist first "joins" the family in order to observe what is occurring. After joining, which technique does the therapist typically use next?
Mapping: the therapist makes an assessment of the family's structure and repetitive patterns of interactions, usually looking for the maladaptive patterns that need to be addressed during restructuring
131
What are the three phases of structural family therapy?
1) Joining 2) Mapping 3) Restructuring
132
What kind of scheduling is a casino using to encourage this gambling bx?
Variable ratio. This schedule provides reinforcement at a varying response rate. The number of game attempts to win at slots varies for each win. (a variable interval schedule provides reinforcement for responses that occur after varying amts of time)
133
A 4 y/o child presents for an initial evaluation with a h/o of school refusal. Which broad-based rating scale is best suited to evaluate anxiety?
Spence Children's Anxiety Scale (normed to the age of 2.5, parent report from age 2.5 - 6) and consists of 35-45 items geared towards assessing anxiety.
134
Age range for the SCARED?
8-18. Looks at GAD, social phobia, panic d/o, and separation anxiety.
135
36-item scale used to assess intensity and frequency of aggression and externalizing bxs as well as sxs of ADHD in children age 2-16. This scale was utilized to measure outcomes in PCIT.
Eyeberg Child Bx Inventory (ECBI)
136
Eyeberg Child Bx Inventory (ECBI) = 36-item scale used to assess intensity and frequency of aggression and externalizing bxs as well as sxs of ADHD in children age Range? This scale was utilized to measure outcomes in PCIT.
2-16
137
This type of aggression is a marked and pervasive tendency to perceive that others are acting with hostile intent. It is typically a result of an angry arousal and is impulsive in nature.
Reactive aggression.
138
Reactive aggression = This type of aggression is a marked and pervasive tendency to perceive that others are acting with hostile intent. It is typically a result of an angry arousal and is impulsive in nature. Tx?
Anger management
139
This type of aggression is rooted in a belief that the youth will get what he/she wants and that other strategies will not work. It is deliberate.
Proactive aggression
140
Proactive aggression = This type of aggression is rooted in a belief that the youth will get what he/she wants and that other strategies will not work. It is deliberate. Tx?
Therapeutic modalities that enhance empathy and decrease antisocial attitudes.
141
Primary enuresis - there is a high rate of spontaneous remission when?
Between ages 5-7 and after age 12
142
What gene is associated with tuberous sclerosis and is linked to ASD?
TSC1
143
Medical conditions that cause ASD can be identified in what percent of cases?
<5%
144
What percent of children with severe chronic medical illness survive into adulthood?
90%
145
What features need to be present at some point to dx Tourette's disorder?
Multiple motor tics and at least 1 vocal tic Must be present at some time during the illness, although not necessarily concurrently. 1 year. No tic free period of more than 3 consecutive months.
146
Onset of Tourette's disorder must occur before what age?
18 years
147
Who was the first person to characterize autism spectrum?
Leo Kanner
148
What part of the brain is responsible for arousal?
Pons
149
What part of the brain is responsible for most physiologic regulations, including body temperature?
Hypothalamus
150
Language is controlled by several areas of the brain, including what two lobes?
frontal and temporal
151
A child can hold her head up when sitting in a chair but cannot sit up on her own on the ground. The child will turn and look at sounds but does not yet say any sounds or words other than cooing. She has just started to reach for objects but is unable to pass them back to her parents. Age?
4 months but not quite 6 months (being unable to sit unsupported is the most common indicator).
152
MOA of mirtazapine?
Antagonism of presynaptic alpha-2-adrenergic inhibitory autoreceptors = noradrenergic and serotonergic activity.
153
Bioavailability of mirtazapine?
50% d/t extensive first-pass metabolism.
154
Common side effects of mirtazapine? (6)
1) mildly elevated ALT and triglycerides 2) weight gain 3) somnolence 4) dry mouth 5) asthenia 6) constipation
155
Telencephalon (3)?
1) Cerebral hemispheres 2) Limbic system 3) Basal ganglia
156
Diencephalon (3)?
1) Thalamus 2) Hypothalamus 3) Optic vesicle
157
Mesencephalon (3)?
1) Red nucleus 2) Substantia nigra 3) Periaqueductal gray
158
Melencephalon (2)?
1) Pons | 2) Cerebellum
159
Myelencephalon (1)?
Medulla
160
A 6 y/o is struggling to make new friends and reports to his mother that he "can't do anything right." Which basic conflict describes this child?
Industry vs inferiority (6-12) Confidence, competence, social skills
161
In what age group do you see trust vs. mistrust?
Birth to 18 months Basic trust
162
In what age group do you see autonomy vs shame?
18 months to 3 years Control and independence
163
In what age group do you see initiative vs guilt?
3 to 6 taking control of the environment, purpose
164
In what age group do you see identity vs role confusion?
12 to 28 Formation of identity, devotion
165
Pica = repeated eating of nonfood substances that are not nutritional for at least how long?
1 month
166
During a family therapy session, the therapist asks the family members to get up and stand physically closer to family members who they felt emotionally closer to and stay distant from those they felt emotionally distant from. This is an example of which technique?
Sculpting
167
First line medication for moderate - severe tics?
Guanfacine or clonidine Antipsychotics are second line
168
Patients with this personality disorder commonly experience over-involvement and intrusive bx by primary caretakers as a child. They were often socially humiliated during childhood, which leads to doubt in their own ability to function independently of others.
Dependent personality disorder
169
Patients who develop this personality disorder often had parents who were emotionally withholding and overprotective or over-controlling. The were often punished and rarely rewarded. They developed sxs as a strategy to avoid punishment.
OCPD
170
A grandiose sense of self-importance is a sx of what personality disorder?
Narcissistic PD
171
A referral to a child psychiatrist is a typical component of an IEP - TRUE OR FALSE?
FALSE
172
LOT benzos are metabolized by the liver, but primarily via what mechanism?
Conjugation
173
A transition plan is a part of an IEP that help with the transition from HS to adulthood. The transition plan starts at what age?
16
174
Common sleep disorder in teens?
Circadian rhythm disorder, delayed-phase type
175
Children and adolescents dx'd with anxiety disorders are how many more times likely to develop a depressive or anxiety disorder in adultlhood?
2-3x more likely
176
At any time, what % of adolescents report some degree of SI?
15-25%
177
What percent of teens attempt suicide?
1-10%
178
Suicide is the 2nd leading cause of death in adolescents and accounts for what % of all deaths?
11
179
22q11.w is associated with a higher risk of early onset schizophrenia. What is the syndrome?
Velocardiofacial
180
Early onset schizophrenia - lifetime risk of developing the illness is ?x higher in first-degree relatives of affected probands?
5-20x
181
A 7 y/o female enjoys forming clubs with other girls, making shared rules, and collecting dolls. Erickson stage of development?
Industry vs Inferiority
182
An 8 y/o girl is working with her mother, who pours a container of lemonade into 2 differently shaped glasses that hold the same volume The child correctly recognizes that although the glasses are different shapes they hold the same volume. Piaget phase?
Concrete operational (7-11 years old)
183
Piaget stage, starts at age 11, includes the use of abstract and hypothetical thinking. The ability to discern major principals and motivations of ideas, theories, or actions allows individuals in this stage to apply them to new and similar situations.
Formal operations
184
Irritability and aggression occur more frequently in bipolar patients with comorbid ADHD when tx'd with stimulants - true or false?
TRUE
185
What medical condition is common in patients with Down Syndrome and may mimic depression?
Hypothyroidism
186
Patients with down syndrome often experience dementia at what age?
40s and 50s
187
ID is generally profound in down syndrome -true or false?
FALSE - can be variable
188
Which model of family therapy is most concerned with triangulation?
Transgenerational family therapy is primarily concerned with helping an individual to differentiate themselves from the family.
189
What is often used in transgenerational family therapy?
Genograms. Transgenerational family therapy is primarily concerned with helping an individual to differentiate themselves from the family.
190
What is triangulation?
When 2 family members join together in opposition to another. It is tx'd with tansgenerational family therapy, which is primarily concerned with helping an individual to differentiate themselves from the family.
191
Is light therapy considered an effective tx?
YES.
192
Light therapy carries a risk of activating patients with what dx?
It carries a risk of activating patients with bipolar disorder.
193
What is the most characteristic primitive defense mechanism in OCD?
Undoing: an attempt to undo or somehow reverse an unacceptable thought, feeling , or action that already occurred by doing an opposite bx. Ex: washing hands multiple times after having an "unclean" thought. By going back and undoing the past, the anxiety over a bx is avoided.
194
A child in the preoperational stage bumps his knee against a desk and kicks the desk, accusing it of hurting him. What is this called?
Animism: the attribution of a soul to plants, inanimate objects, and natural phenomena. The child is egocentric and assumes all of the world thinks as he/she does, including inanimate objects.
195
Most sxs of acute stress will dissipate within 1 month following a tragedy - what % of children will continue to have sxs after a month?
30%
196
What is the general natural history of Tourette's syndrome?
Peaks at age 12 and then improves
197
Tourette's resolves by age 18 in about what % of children?
50%
198
Tourette's syndrome occurs in about what percent of children?
0.5%
199
Tourette's syndrome affects males more than females by a ratio of?
4:1
200
What mood stabilizer slows cardiac conduction and should be avoided in patients with high-grade atrioventricular block and sinus syndrome?
Carbamazepine
201
SIADH and hyponatremia can occur with which mood stabilizer?
Carbamazepine
202
Norfluoxetine, the metabolite of fluoxetine has a half life of up to how many days?
16
203
Fluoxetine is what percent protein bound?
94.5%
204
Why is fluoxetine contradindication within 5 weeks of thioridazine use?
QTc prolongation
205
Fluoxetine dosing for young children?
5 mg/day, 10 mg/day for older children
206
Form of encouragement that is used to convey the therapist's high level of confidence in a patient
Exhortation
207
MOA for which mood stabilizer - inhibits glutamate and voltage-gated sodium channels
Lamotrigine
208
What mood stabilizer increases GABA in the brain?
Depakote
209
Which mood stabilizer exerts its effects through the inhibition of voltage-dependent sodium channels and presynaptic sodium channels
Carbamazepine
210
How does the response to ECT vary between adolescents and adults?
Response appears to be similar
211
Before ECT is used, what needs to happen?
2 child and adolescent psychiatrists who are not the primary caregivers for the adolescent should be consulted and should agree that ECT is indicated
212
What is the most common genetic cause of ID?
Down Syndrome (Fragile X is the most common genetic cause of ID in boys).
213
Which gene is associated with developing psychosis after using cannabis?
AKT1
214
Which gene has been reported to interact with stressful life events and childhood maltreatment in the development of depression?
BDNF
215
Which gene may sensitive the developing brain to the pathogenic effect of CMV in utero, leading to schizophrenia in adulthood?
CTNNA3
216
Which gene, that codes a co-chaperone of the glucocorticoid receptor, was reported to sensitize individuals to developing PTSD after exposure to childhood maltreatment?
FKBP5
217
Which therapy approach to substance abuse in adolescents has the most empirical support?
Family therapy
218
During the Oedipal phase of development, what is characteristic of play? (4)
1) child's sense of place within the family 2) theories and feelings about babies and their origins 3) anatomical differences between the genders 4) curiosity and excitement associated with genital sensations 4) competition and rivalry
219
A RTC is designed to evaluate the relationship between HTN and differing doses of velafaxine. A linear regression model is plotted with venlafaxine on the X-axis and BP on the Y-axis. R is calculated as 0.6. How should the coefficient of determination be interpreted?
36% of variance in BP can be explained by venlafaxine dose. (calculated by the square of the R value). Variance in Y that can be explained by X.
220
The TADS study indicated that what percent of depressed youth respond to initial tx w medication?
60% | CBT + meds = 71%
221
A loaded gun at home confers a ?x higher risk in youth without any psychopathology?
30x
222
Psychological factors contributing to suicide risk?
1) impulsive aggression 2) hopelessness 3) neuroticism 4) same-sex attraction
223
patients who have first-degree relatives who have completed suicide have a ?x greater risk for suicide attempt?
4-6x
224
Genetic factors that elevate risk of suicide? (3)
1) altered serotonergic function 2) altered adrenocortical function 3) blunted sleep-stimulated growth hormone secretion
225
A white female can throw a ball overhand - this milestone is achieved by 50-90% of children by what age?
24 months
226
What are the 5 core principles of MI?
1) express empathy 2) develop discrepancy 3) avoid argumentation 4) roll w resistance 5) support self-efficacy
227
Those suffering from this condition have delayed motor development, jerky limb movements, epilepsy, face abnormalities, happy demeanor, and laugh frequently.
Angelman syndrome (maternal ch. 15)
228
Approx what % of Americans have reported PTSD at some point in their lives?
8%
229
Somatic symptom disorder is observed in what percentage of female first-degree relatives of patients with somatic symptom and related disorders?
10-20%
230
Somatic symptom disorder - prevalence in females?
0.2-2%
231
Somatic symptom disorder - prevalence in males?
< 0.2%
232
What cell type forms the blood-brain barrier and aids neuronal migration during development?
Astrocytes: type of glial cells that are responsible for the development and framework of the neurons. They outnumber neurons 5:1 and contiguously tile the entire CNS.
233
What three cellular elements of the brain microvasculature compose the blood-brain barrier?
1) endothelial cells 2) astrocyte end-feet 3) pericytes
234
Aggression in a 5 y/o with autism - only medication approved for this age?
Risperidone | abilify is approved for 6+
235
What condition is considered high risk for associated hearing defects?
Persistent fetal circulation
236
When is a PTSD dx considered "with delayed expression"?
when PTSD criteria is not met until at least 6 months after the event
237
What is the primary reason to decrease psychotropic medication doses in children with liver and kidney disease?
Decreased albumin binding: most psychotropic medications are highly protein bound (with the exception of lithium, methylphenidate, venlafaxine, depakote, gabapentin, and topiramate)
238
Which medications are NOT highly protein bound? (6)
lithium, methylphenidate, venlafaxine, depakote, gabapentin, and topiramate
239
hepatic diseases impact drug distribution through what three ways?
1) changes in blood flow 2) protein binding 3) volume of distribution
240
Uridine glucuronosyltransferase enxymes play a minor role in drug metabolism with the exception of what three medications?
Lamotrigine, morphine, and lorazepam
241
Why do extended release medications have fewer side effects?
Due to more gradual increases in the plasma concentration
242
Common side effects of depakote? (5)
1) alopecia 2) rash 3) GI 4) neurological 5) ophthalmological
243
Absolute contraindications for depakote?
1) hepatic disease 2) known urea cycle disorders 3) pregnancy 4) PCOS in females of child bearing age
244
Does depakote have FDA approval for mania in adolescents?
No, only approved for seizure disorder
245
As many as what percent of boys between ages 8-12 may have transient tics?
15%
246
A 13 y/o F has been dx'd w MDD, single, moderate. TX?
Prozac (8+) | Escitalopram // lexapro (12+)
247
Which two medications are indicated for OCD in children and adolescents?
Sertraline (6+) | Fluvoxamine (8+)
248
6F w OCD, tx?
Sertraline (6+) When she turns 8... Fluvoxamine (8+)
249
Form of non-associative learning whereby repetitive stimuli elicit weakening behavioral responses if the stimuli do not reinforce or punish the bx
Habituation
250
Form of non-associative learning whereby repetitive stimuli elicit increasingly powerful responses.
Sensitization
251
Puberty occurs how much earlier in females than males?
1.5 years
252
Puberty in females unfolds in what order? (3)
1) breast bud development 2) pubic hair growth 3) menache
253
Clozapine is a pregnancy class B drug - what does this mean
It has not been shown to cause birth defects
254
Lithium: what percent of the dose is excreted unchanged in urine?
90-98%
255
Lithium: in young patients with normal renal function, the volume of distribution is what percent greater in adolescents that for adults?
20%
256
Clozapine - when can drug-induced fever and tachycardia occur?
In the first few days of tx
257
Seizure risk with clozapine tx - what percent of patients on doses > 600 mg/day will have seizures?
4-6%
258
Agranulocytosis occurs mostly when with clozapine?
first 6 months of tx
259
Agranulocytosis is more common in what groups (3)?
1) Ashkenazi Jewish 2) advanced age 3) women
260
Is TD associated with clozapine?
No, the prevalence is low and the severity is relatively mild, with no or mild self-reported discomfort. Can be used as tx/reduce sx if patient is switched to clozapine from another antipsychotic
261
"the extent to which a theory, result, conclusion, or test/measurement is credible and corresponds accurately to the population of interest" describes what statistical term?
Validity
262
The test measured what it was supposed to measure in the initial population
Internal validity
263
The results can be generalized beyond the immediate study to other populations
External validity
264
Determines if a test will measure the problem in question
Construct validity
265
Defined as the overall consistency or reproducibility of a measure
Reliability
266
A test can be _____ without being ____ but a test cannot be ____ unless it is _____
A test can be reliable without being valid but a test cannot be valid unless it is reliable
267
The parents of a student request an evaluation for a 504 plan but then disagree with the school's findings and want a second opinion. Who pays for the second opinion?
Under section 504, the school has few obligations for second opinions and would not have to pay for any second opinion that the parents might request. Were it an IEP the school would be required to pay for an IEE.
268
You see a patient in the hospital with conversion disorder. Tx? (2)
1) Reassurance (emphasize to the family that her sxs are involuntary) 2) Reasonable rehabilitation Confrontation about the sxs is contraindicated. Psychotherapy might be useful but may also be contraindicated if the patient is resistant. Meds could be suggested later for anxiety or depressive sxs.
269
Conversion disorder - duration of sxs?
Usually remits spontaneously within 2 wks in hospitalized patients and it is unlikely to persist more than a year
270
WISC can measure intelligence - age range?
6-16
271
What test assesses academic achievement by testing reading, writing, math, and oral language?
WIAT-II
272
The WIAT-II test assesses academic achievement by testing reading, writing, math, and oral language. Age range?
4-85
273
What test can be paired with the WISC to measure both intelligence and academic achievement to look for any discrepancies?
WIAT-II: assesses academic achievement by testing reading, writing, math, and oral language
274
What is the half life of guanfacine in children?
12-14 hours
275
Guanfacine is typically dosed how many times her day?
2-3 times (half life is 12-14 hours)
276
Half life of clonidine?
8-12 hours
277
Clonidine is dosed how many times per day?
3-4 (half life is 8-12 hours)
278
How long do the behavioral effects of clonidine last?
3-6 hours
279
Hypotension and sedation is worse in clonidine or guanfacine?
Clonidine
280
Ipecac causes cardiac problems through what mechanism?
Damaging myocardial muscle cells. A toxic component of ipecac (emetine) accumulates in the myocardium. Sxs of ipecac toxicity include chest pain, dyspnea, hypotension, supraventricular tachycardia, atrial premature contractions, flattened or inverted T-waves, prolonged QT and PR intervals, ventricular tachycardia, cardiac failure, pericardial effusion, pulmonary congestion, and cardiac arrest.
281
Side effects of ipecac? (2)
Cardiomyopathy and elevated liver enzymes
282
THe vanderbilt screens for what three disorders?
ADHD, conduct disorder, and ODD
283
The SNAP-IV rating scale screens for what?
ADHD and ODD
284
The SNAP-IV rating scale screens for ADHD and ODD in what age range?
6-18
285
The Attention Deficit Disorders Evaluation Scale (ADDES-3) screens for ADHD - age range?
4-18
286
The genetic syndrome appears to become more pronounced with successive generations. A classic ex is fragile X.
Anticipation
287
Minuchin is the main proponent of what type of family therapy?
Structural
288
Psychoeducational family therapy is associated with what two people?
1) Carol Anderson | 2) William McFarlane
289
Behavioral family therapy is associated with what two people?
1) Robert Liberman | 2) Lawrence Weathers
290
Narrative family therapy is associated with what two people?
1) Michael White | 2) David Epston
291
Systemic family therapy is associated with what two people?
1) Mara Selvini Palazolli | 2) Luigi Boscolo
292
What is the most important factor in group therapy related to positive therapeutic effects?
Cohesion - a sense that the group is working together toward a common goal
293
In group therapy, the act of one member helping another, putting another person's needs before one's own, and learning that there is value in giving to others
Altruism
294
Prader-Willi syndrome: patients have short stature w hypogonadism, hyperphagia, and obesity. The genetic abnormality in what percent of patients is a deletion at ch. 15?
70%
295
Prader-Willi syndrome: hyper or hypo gonadism?
Hypogonadism
296
The sensorimotor stage of child development occurs at which age, according to Piaget?
Birth through 18-24 months
297
A child is able to jump up and down. This milestone is acheived by 50-90% of children by which age?
24 months
298
What part of the brain is primarily responsible for visual and spatial recognition?
Parietal lobe
299
The parietal lobes are key areas for what three things?
1) Sensory integration 2) Somatosensory function 3) Visual and spatial recognition
300
The temporal lobes are the key areas for the brain for what two things?
1) Hearing | 2) Naming
301
The occipital lobe is the key area for what?
Visual functions
302
The frontal lobe is the key area for what 5 things?
1) Executive function 2) Social conduct 3) Judgment 4) Insight 5) some motor function
303
According to Minuchin, which family dynamics predict the development of "psychosomatic families"?
Enmeshment, rigidity, overprotectiveness, and the lack of conflict resolution.
304
Most family therapies of what disorder have been developed based on the classical description of the "psychosomatic" family by Minuchin?
Eating disorder Enmeshment, rigidity, overprotectiveness, and the lack of conflict resolution.
305
A large retrospective cohort study indicated that children and young adults do or don't have a higher risk of cardiovascular events?
DO NOT
306
Atomoxetine - contraindications?
patients with a history of serious structural cardiac abnormalities, cardiomyopathy, arrhythmia, and other cardiac issues.
307
Atomoxetine's effect on HR and BP
Increases
308
Atomoxetine increases HR and BP through what mechanism?
decreasing the reuptake of norepinephrine
309
Guanfacine ER can cause AV block, bradycardia, hypotension, orthostasis, sinus node dysfunction, and syncope. Dose dependent?
YES
310
Guanfacine ER can cause AV block, bradycardia, hypotension, orthostasis, sinus node dysfunction, and syncope. When are the side effects most common?
The first few weeks of treatment
311
What is chronotherapy?
used in people with circadian rhythm sleep disorders. It involves intentionally delaying going to sleep by two to three hours on successive days until you are able to fall asleep at the desired bedtime. This can be difficult to do at home and is sometimes done in a hospital setting. After this, you must strictly enforce this sleep-wake schedule.
312
Which form of child maltreatment confers the highest risk of the child eventually attempting suicide?
Sexual abuse confers the highest risk of a poor outcome for the child. The risk of SA is nearly 10x higher for sexually abused children compared to other types of abuse.
313
The risk of SA is nearly ?x higher for sexually abused children compared to other types of abuse.
10x Abuse by closer relatives also tends to carry a poorer prognosis.
314
The cerebral hemisphere originate from which of the following developmental divisions of the CNS?
Telencephalon
315
The 6 secondary divisions occur around what week of gestation?
5th
316
According to Mahler, during what age range does hatching occur?
5-9 months
317
Increased rates of persistent pulmonary HTN have been associated with SSRI use at which stage of pregnancy?
Late in pregnancy. The absolute risk was found to be low.
318
What IPT focus area is focused on conflict in significant relationships?
Role dispute
319
The study sample is most representative of the overall population when what time of sampling is used?
Random sampling
320
samples may allow estimations of what in resulting statistics?
Error
321
The "threshold of responsiveness" is a temperamental dimension according to Chess and Thomas - what does it mean?
Indicates the degree of environmental change that must occur to elicit a response from the child.
322
A child is able to sleep with a TV on, in any position in bed, and at a wide range of temperatures. According to Chess and Thomas what is this referring to?
A high "threshold of responsiveness"
323
16M w new-onset paranoid schizophrenia. What is the most characteristic primitive defense mechanism in psychosis?
Projection: attributing undesirable thoughts and feelings to others to avoid facing them or to reduce anxiety around them. In psychosis, individuals may attribute their own thoughts to hallucinations and perceive the hallucinations to be something separate from them, thus making this a form of projection.
324
The most frequently studied genes implicated in the development of substance use disorders, including alcohol use disorder, encode which substances? (2)
1) alcohol dehydrogenase | 2) aldehyde dehydrogenase
325
Alcohol dehydrogenase metabolizes what?
ETHANOL TO ACETALDEHYDE
326
Aldehyde dehydrogenase metabolizes what?
Acetaldehyde to acetate
327
Alcohol dehydrogenase and aldehyde dehydrogenase are the most frequently studied genes implicated in the development of substance use disorders. This work has confirmed the role of these genes in what pathway?
Dopamine pathway
328
What converst L-DOPA to dopamine?
DOPA decarboxylase
329
Gain-of-function polymorphisms of the SLC6A4 promoter have been linked to what disorder?
OCD | also alcohol consumption
330
What is the rate limiting step in serotonin synthesis?
Tryptophan hydroxylase
331
Bx that serves a purpose for the individual and is ongoing
Functional bx
332
The MOA for the addictive component of cannabis?
Releases dopamine in the mesolimbic system
333
Cannabis triggers the release of dopamine in what system which causes addiction?
The mesolimbic
334
What is the MOA of cannabis?
Activation of endogenous cannabinoid receptors in the brain.
335
What substances are partial 5HT receptor agonists?
LSD and other hallucinogens
336
4M is noted by his parents to have lost his ability to speak. He was previously healthy and had average language skills for his age. An EEG revealed electrographic seizures, but he has not been noted to have seizures clinically. Dx?
Landau-Kleffner syndrome: infantile acquired aphasia, acquired epileptic ahasia, or aphasia with convulsive d/o.
337
Landau-Kleffner syndrome: 4M is noted by his parents to have lost his ability to speak. He was previously healthy and had average language skills for his age. An EEG revealed electrographic seizures, but he has not been noted to have seizures clinically. Age range of children affected?
3-7 years
338
Landau-Kleffner syndrome: 4M is noted by his parents to have lost his ability to speak. He was previously healthy and had average language skills for his age. An EEG revealed electrographic seizures, but he has not been noted to have seizures clinically. Affects what areas of the brain?
Broca's and Wernicke's
339
Landau-Kleffner syndrome: 4M is noted by his parents to have lost his ability to speak. He was previously healthy and had average language skills for his age. An EEG revealed electrographic seizures, but he has not been noted to have seizures clinically. Can be difficult to dx and misdx'd as what?
Autism.
340
Skipping is first seen at what age?
5 y/o
341
Being able to draw a circle - age?
3 y/o
342
Correctly naming 4 colors - age?
5 y/o
343
MR spectroscopy is used to evaluate which parameter?
Biochemical concentrations of brain metabolites. Several different metabolites can be measured to differentiate between tumor types, including amino acids, lipids, lactate, alanine, N-acetyl aspartate...
344
MR spectroscopy is used to determine the biochemical concentrations of brain metabolites. It is commonly used to evaluate what?
Brain tumors
345
Persistent depressive disorder: depressed or irritable mood + 2 of the following: (6)
1) poor appetite or overeating 2) insomnia or hypersomnia 3) low energy or fatigue 4) low self-esteem 5) poor concentration or difficulty making decisions 6) feelings of helplessness
346
Persistent depressive disorder: depressed or irritable mood + 2 mood sxs for how long?
At least 1 year
347
Test that reveals underlying motives, concerns, and social worldview through the stories a patient makes up about ambiguous pictures of people
Thematic Apperception Test (TAT) - projective psychological test
348
Test that measures a person's emotional functioning
Rorschach test ("inkblot")
349
Tests cognitive ability and intelligence
Stanford-Binet Intelligence Scale
350
What percent of offspring are affected when one parent has a h/o prolonged noctural enuresis?
50%
351
What percent of offspring are affected when both parent have a h/o prolonged noctural enuresis?
75%
352
Electrolytes in laxative abuse - sodium?
Increased or normal
353
Electrolytes in laxative abuse - K+?
Decreased
354
Electrolytes in laxative abuse - Cl-?
Increased or decreased
355
Electrolytes in vomiting - sodium?
Increased, decreased, or normal
356
Electrolytes in vomiting - K+?
decreased
357
Electrolytes in vomiting - CL-?
Decreased
358
Electrolytes in vomiting - bicarbonate?
Increased
359
pH in vomiting?
Increased
360
pH when using diuretics?
Increased
361
Sodium when using diuretics?
Decreased or normal
362
K+ when using diuretics?
Decreased
363
Chloride when using diuretics?
Decreased
364
Bicarbonate when using diuretics?
Increased
365
What percentage of preschoolers with poor peer relationships and inadequate problem-solving patterns predictive of impulsive aggression have a h/o physical abuse?
20-25% Planned aggression starts approx 2 years later and is driven by aggressive role models and a positive valence of aggression rather than the physical abuse.
366
A family complains that their 15 y/o daughter refuses to listen when they ask her to do her homework. During a family therapy session, the therapist asks the parents to pretend to ask their daughter to do her work and for the daughter to pretend to refuse. What technique is being used here?
Paradoxical intervention. The idea is that patients can sometimes believe that such conflicts are out of their control. Having the patients purposely create the situation is voluntary and brings the sx on in a controlled way. This can help patients work through the sx during the sessions and also perhaps come to see it as under voluntary control.
367
A child can walk backwards. This milestone is scheived by 50-90% of children by which age?
16-18 months
368
Mahler's separation-individuation is subdivided into 3 phases - what are they?
1) hatching 2) practicing 3) rapproachement
369
What are the comparative rate of youth incarceration for children raised in intact families as compared to stepmother families?
1:4
370
Prenatal exposure to what influences human sexual orientation?
Androgenic hormones
371
In exposure with response prevention, immediately following an exposure, what response is being prevented?
Compulsive bxs.
372
What does response prevention mean?
Refraining from compulsions, avoidance, or escape bxs. The response most commonly prevented is a compulsion that acutely reduces anxiety but perpetuates the disorder by making the sufferer believe that the compulsion is needed to reduce anxiety or some feared consequence of not performing the compulsion by addressing the anxiety or anxious thoughts.
373
What form of therapy specifically states that the goal of the therapist is to initiate what happens during therapy and take direct responsibility for influencing people?
Strategic family therapy
374
A specific form of brief psychotherapy that focuses on providing solutions to practical problems, such as conduct problems and drug use.
Strategic family therapy
375
This type of therapy was founded by Jay Haley and encourages the therapist to take an active role, initiate what will occur during therapy, and take direct responsibility for influencing people.
Strategic family therapy
376
A 4 y/o child presents with diffuse weakness, cerebellar ataxia, partial ophthalmoplegia. Vitamin deficiency?
Vit E.
377
What is the only common vitamin that causes spinocerebellar degeneration? Patients may have myelopathy w posterior column lesions, a positive Babinski sign, and loss of vibration and joint position sense.
Vit E.
378
It takes approx 15-20 years for adults to deplete vit Ed stores, but only 2-3 years for this to occur in children. Deficiency states may be seen in what type of disorders?
Fat malabsorption Ex: Bassen-kornzweig syndrome, Ataxia with isolated vit E deficiency (AVED)
379
Babies with this vitamin deficiency may have increased intracranial pressure with lethargy, night blindness, and "bitot spots" (white foamy lesions) on the conjunctiva.
Vit A
380
Children with this vit deficiency develop irritability, an exaggerated startle response, and seizures refractory to conventional anticonvulsants. They develop normally one the deficiency is treated.
B6 (pyridoxine)
381
Vitamin B6 (pyridoxine) may be dietary, congenital, or drug-induced - what three medications?
1) isoniazid 2) hydralazine 3) penicillamine
382
This vitamin deficiency manifests as proximal weakness, which may include neck muscles. Patients may have waddling gait. EMG demonstrates short-duration, low-amplitutde, polyphasic motor unit potentials w/o spontaneous activities.
Vit D
383
Vit D deficiency made result from?
1) hyperparathyroidism 2) hypophosphatemia 3) chronic renal failure 4) use of certain anticonvulsants 5) malabsorption 6) low dietary intake 7) lack of sun exposure
384
Lab tests reveal elevated alkaline phosphatase level and a compensatory increase in parathyroid hormone. Vit deficiency?
Vit D
385
Vitamin deficiency: diarrhea, dermatitis, and dementia. Patient may also exhibit spasticity, positive Babinski, gegenhalten, and startle myoclonus. Results from corn as the sole carbohydrate source.
Pellagra: nicotinic acid (niacin) deficiency
386
This vit deficiency may also be associated with alcohol abuse and is suspected when tx with thiamine does not improve cognition.
Pellagra: nicotinic acid (niacin) deficiency
387
What has been shown in one well-designed study to lower the risk of progressing from prodromal psychotic sxs to full blown schizophrenia.
Omega-3 fatty acids
388
An examiner is playing toys with a child and hides the toy. The child begins to look for the toy. Stage?
Sensorimotor. One of the main accomplishments of this stage was achieving object permanence.
389
Around what age does object permanence occur?
8 months (sensorimotor stage)
390
In a stuporous state, the patient would arouse to response purposefully to what?
Vigorous external stimulation
391
Locked-in syndrome occurs when a focal injury occurs where? A conscious patient is unable to move muscles, but can voluntarily blink and make vertical eye movements.
To the base of the pons.
392
In this state the patient has normal sleep-wake cycles and is arousable but has no awareness or apparent cognitive function. It may occur as a transition between coma and recovery, or between coma and brain death or death.
Persistent vegetative state
393
This occurs when the patient is able to follow with his/her eyes but does not initiate other movements or obey commands
Akinetic mutism
394
A child is able to run but falls occasionally. This milestone is achieved by 50-90% of children by what age?
18 months
395
What percentage of children with oppositional defiant disorder will develop conduct disorder?
30%
396
A lesion of which structure will result in prosopagnosia?
Fusiform gyrus: right and/or left, is associated with face recognition. The "fusiform face area" is located on the ventral stream on the ventral surface of the temporal lobe, on the lateral side of the fusiform gyrus.
397
Destruction to the inferior parietal lobule of the dominant hemisphere results in what syndrome?
Gerstmann's syndrome: right-t0-left confusion, finger agnosia, dysgraphia and dyslexia, dyscalculia, contralateral hemianopia, or lower quadrantanopia.
398
Rudimentary gender identity is usually formed around what age?
3
399
Medication approved for ODD?
There is no FDA-approved medication for ODD.
400
In young children (prior to adolescence), is ODD more prevalent in males or females?
Males (1.4:1)
401
In adolescents, is ODD more prevalent in males or females?
Same
402
A pediatric patient is scheduled for follow up care, but has a large outstanding bill. What do you do?
Administer care as needed. | must given reasonable written notice to allow the location of an alternative source of care
403
Fetal alcohol syndrome occurs at a rate of what % per live birth?
1%
404
CNS abnormalities in FAS?
1) abnl brain size and shape 2) smaller cerebellar and ventricular size 3) agenesis of the corpus callosum
405
A broad type of sleep disorders involving difficulty falling or remaining asleep, which can lead to excessive sleepiness during the day due to the reduced quantity, quality or timing of sleep.
Dyssomnia
406
Sleepwalking disorder is what type of disorder?
Parasomnia
407
Sleep-wake disorders include what 10 disorders?
1) insomnia 2) hypersomnolence 3) narcolepsy 4) breathing-related sleep 5) circadian rhythm 6) non-REM sleep arousal 7) REM sleep bx 8) restless legs 9) nightmare 10) substance/medication induced
408
ODD comorbidity with ADHD - what percent?
50%
409
ODD - do most kids with ODD have insight that their bx is problematic?
No
410
9F who is otherwise healthy, is crying after skinning her knee on the playground. She then has sudden onset right-sided face, arm, hand, and leg weakness and numbness, which resolves over the following 25 minutes. Angiogram = stenosis of the supraglenoid ICA and MCA with the development of collateral circulation. Dx?
Moyamoya disease: consists of progressive non-atherosclerotic b/l stenoses of the distal internal carotid arteries and trunks of the anterior and middle cerebral arteries. Collaterals develop at the base of the brain w a characteristic "puff of smoke" appearance on angiography.
411
This disease is most common in Japanese girls and may have autosomal recessive inheritance. Collaterals develop at the base of the brain w a characteristic "puff of smoke" appearance on angiography. Dx?
Moyamoya disease: consists of progressive non-atherosclerotic b/l stenoses of the distal internal carotid arteries and trunks of the anterior and middle cerebral arteries. 9F who is otherwise healthy, is crying after skinning her knee on the playground. She then has sudden onset right-sided face, arm, hand, and leg weakness and numbness, which resolves over the following 25 minutes.
412
17 minor who has enlisted in the Army arrives at the ED in police custody. He is suspected of ingesting ilicit medications to avoid arrest. The police request a NG aspirate for evidence, the patient refuses. What do you do?
Honor the patient's wishes and do not proceed with care. The patient is likely emancipated from his parents since he joined the army. He is therefore authorized to consent to medical care.
413
Individuals with ASD have weak central coherence - what does this mean?
Poorly integrate information into meaningful wholes
414
Individuals with ASD typically have deficits in the theory of mind tasks - true or false?
True
415
MRI brain of a patient with ASD shows? (2)
1) larger brains | 2) aberrations in white matter tract development
416
Rates of EEG abnormalities and seizures in patients with ASD?
20-25%
417
13F w anxiety. She has a h/o seizures since age 2. She is overly friendly and overly excitable. She has poor language skills and was dx'd w moderate ID? What genetic marker is responsible for this condition?
15q11-13 maternal deletion. Angelman syndrome. "Happy puppet syndrome."
418
The firing of dopamine-releasing neurons, with cell bodies in the ? and axon terminals in the nucleus accumbens, marks the importance or salience of a reward and signals that a rewarding event is about to occur.
VTA
419
The firing of dopamine-releasing neurons, with cell bodies in the VTA and axon terminals in the ?, marks the importance or salience of a reward and signals that a rewarding event is about to occur.
nucleus accumbens
420
Endogenous opiod neuropeptides are controlling links of the ? and ?.
1) Nucleus accumbens | 2) Amygdala
421
A psychiatrist is designing a study comparing the reflexes of subjects before and after they are exposed to dextroamphetamine. The subjects will be asked to tap a screen when a shape appears on the screen, and their reaction time will be recorded. What statistical test will provide the best comparison of the results?
Paired t-test. Best for comparing whether the averages of 2 groups of data are statistically different from each other, specifically when the data are linked together in some way (ex: comparing tx effects in the same group of people before and after exposure to a drug). In this case, the effects are measured from the same people, so the data are considered linked together.
422
Statistical measure of how close a series of data comes to a calculated regression line. It tells how well data fit along a straight line or curve and is often used for dose-response studies.
R^2
423
R^2 is a statistical measure of how close a series of data comes to a calculated regression line. It tells how well data fit along a straight line or curve and is often used for what type of studies.
dose-response
424
Statistical method used to compare the means of multiple sets of data at once and determine whether they are likely to be different due to chance. This would be useful when comparing the means of multiple groups exposed to multiple different doses.
ANOVA
425
This statistical test is best used for comparing categorical variables - this is usually something like a yes/no question, such as whether a subject is depressed or not.
Chi-squared test
426
Infantile anorexia interferes with which important developmental event?
Somatopsychological differentiation: the ability to differentiate sensations in the body.
427
This disorder usually occurs between 6 months and 3 years and can vary between meals and feedrs. The infant's feeding is directed by his/her emotional needs instead of physiological sensations of hunger and satiety. He/she fails to develop somatopsychological differentiation, which is the ability to differentiate sensations in the body.
Infantile anorexia
428
Has a pincer grasp - age?
9 months
429
Put hands together, has a social smile, recognizes parents, laughs - age?
3 months
430
Rolls from tummy to back - age?
4 months
431
Sits unsupported, rolls in both directions, begins to crawl, reaches and passes objects from one hand to another, babbles with strings of vowel and consonant sounds - age?
6 months
432
May develop stranger anxiety, stands unassisted, has pincer grasp - age?
9 months
433
walks, says "mama" and "dada" -age?
12 months
434
Runs, stacks 2 cubes, removes clothing, has a 6-word vocabulary - age?
15 months
435
The most effective tx for bullimia overall is what?
CBT
436
What medication is FDA-approved for bullimia?
Fluoxetine (an SSRI alone is not conisdered adequate tx for bullimia - need CBT)
437
For MI, what does OARS stand for?
Open-ended questions Affirmations Reflective listening Summaries
438
The neurotransmitter produced in the tuberomammillary nucleus is responsible for what systemic reaction?
Itching - histamine!
439
Sweating is mediated by what receptors?
Muscarinic Ach receptors (Ach is produced in the nucleus basalis of Meynert).
440
Where is Ach produced?
Nucleus basalis of Meynert
441
Bradycardia is mediated by what receptors?
Muscarinic Ach receptors (Ach is produced in the nucleus basalis of Meynert).
442
Nausea is mediated by what neurotransmitter?
Serotonin, which is produced in the raphe nuclei
443
Where is serotonin produced?
Raphe nuclei
444
Arterial vasoconstriction is mediated by what neurotransmitter?
Norepinephrine, which is produced in the locus coeruleus
445
Where is norepinephrine produced?
Locus coeruleus
446
What factors are most predictive of an ultimate outcome in children with autism? (2)
1) Presence of speech by age 5 | 2) Severity of ID
447
A child is referred for seizures, ID, developmental delay, and behavioral problems. + Fhx. If the patient's skin was examined under a Wood's lamp, which classic finding may be revealed?
Hypopigmented macules (ash leaf spots) Up to 95% of patients with tuberous sclerosis complex have one of the following lesions: hypopigmented macules, angiofibroma, Shagreen patches, or brown fibrous plaque on forehead.
448
A child is referred for seizures, ID, developmental delay, and behavioral problems. + Fhx. One of the following lesions: one of the following lesions: hypopigmented macules, angiofibroma, Shagreen patches, or brown fibrous plaque on forehead. Dx?
Tuberous sclerosis
449
Most evidence-based therapies for adolescent substance use disorder? (2)
Family-based therapy | Motivational enhancement therapy/brief intervention
450
A child presents for evaluation and is speaking in full sentences with mostly clear pronunciation. The parents report that the child has been riding his tricycle and feeding himself. The child is able to put his shoes on independently, using 10 blocks to build a tower, and copy a circle. The child alternates footsteps up and down the stairs and hops off the last step. Age?
36 months
451
Child is learning to stand independently, can begin dressing, and may also be able to use single words - age?
12 months
452
Child is walking more independently but still occasionally falls and can build towers 3 blocks high. The child is able to understand basic commands. Age?
18 months
453
Child has begun to run and can kick a ball. These children are learning to go up and down stairs independently. Towers composed of about 7 blocks can bow be built. There is also the "no" phase. Children at this age can start pulling on a shirt or pulling up pants. Age?
2 y/o
454
Child is able to skip, draw a person, completely dress and undress, and speak with nearly full fluency. Age?
5 year old
455
EPS occurs in what percent of pediatric patients on first-generation antipsychotics?
75%
456
What is the opposite of enmeshment?
Disengagement
457
In structural family therapy, the therapist goes through 3 techniques - joining, diagnosing, and restructuring. What occurs during restructuring?
The therapist attempts to promote new patterns within the family that will help it to be more flexible and functional. Therapist promotes growth and encouragement in individuals for the building of family support.
458
Individuals w ASD have decreased formation of what type of cells in the cerebellum?
Purkinje cells
459
Individuals w ASD have decreased formation of Purkinje cells in what part of the brain?
Cerebellum
460
Brain size in patients with ASD?
Increased overall brain size
461
Patients with ASD experience accelerated growth of what during infancy?
the head
462
Abnormalities in the synthesis of what neurotransmitter is seen in patients with ASD?
Serotonin
463
According to Chess and Thomas - what are the three types of children?
Difficult, easy, slow-to-warm up
464
What bx most commonly precedes an adolescent SA?
Confessing suicidal thoughts to friends
465
is there research to indicate that inpatient hospitalization reduces suicidality?
No
466
The increase of SSRI rxs correlated with a significant increase or decrease in completed suicides in teens?
Decreased
467
Most individuals with the DSM dx of "profound ID" have what feature?
Most people have an identified neurological condition that accounts for their ID
468
Which influential child therapist stressed that child development was a continuous cumulative process rather than defined stages, initiating the concept of "developmental lines" ?
``` Anna Freud (interaction between internal and environmental influences) ```
469
This theorist postulated that there are several developmental lines that a child moves along (development between infant and mother, infant and his/her own body).
Anna Freud
470
How often does the FDA recommend following up with a youth started on an antidepressant?
Every week for the first month and then every other week thereafter
471
When ending with a patient, written notice should be given, preferably by certified mail, with a brief explanation for termination of the relationship and an agreement to continue to provide tx and access to services for a reasonable length of time - how much time?
30 days
472
What percentage of patients with ID fit the DSM dx for severe ID?
3-4%
473
What is the most common psychiatric dx in children?
ADHD
474
Prevalence of ADHD dx?
9.4% of children ages 2-17
475
What is the leading inherited cause of ID?
Fragile X
476
What structure is responsible for temperature control?
Hypothalamus
477
What structure is responsible for the physiologic regulation of much of the body - sleep, hydration, and temp.
Hypothalamus
478
What structure in the body controls arousal, sleep-wake cycles, respiration, swallowing... communication been different parts of the brain. Locked in syndrome!
Pons
479
Eyes in opioid intoxication?
Miosis
480
Eyes in opioid w/d?
Mydriasis
481
Standards that apply to > 95% of the time and are based on rigorous empirical evidence and/or overwhelming clinical consensus
Minimal standards
482
What terms means "apply up to 75% of the time and should usually be considered, but there are significant exceptions to their universal application"
Clinical guidelines
483
What establishes a recommendation of "options"?
They are acceptable but not required and may have insufficient empirical evidence
484
Why should atypical neuroleptics (antipsychotics) be tapered slowly? (2)
1) allow for adjustment to lowered dose | 2) prevent w/d akathsia
485
When does akathisia typically present?
After a few weeks of tx
486
When does dystonia typically present?
Within the first few days of tx
487
when does TD typically present?
After years of tx
488
A young child presents with a dramatic increase in aggression and seems confused. He eventually has a seizure. Imaging shows diffuse changes in one of the temporal lobes. Cause?
Herpes encephalitis HIV tends to be more non-specific and Tuberous sclerosis would usually show district lesions
489
Sleep terror disorder usually begins in children in what age range?
4-12 years
490
How old must you be to be dx'd with ASPD
18 years old
491
14M has intense expressions of emotion and chronic feelings of emptiness and anger towards himself for being "a loser" with no purpose in life. The therapist notes that during sessions, she tends to become angry with the patient and even criticize him for his inability to set goals. Which process is occurring?
Projective identification. When a patient projects unwanted or intolerable aspects of himself/herself onto another person, and when he/she induces the other person to take on those characteristics and play the role the patient has assigned to him/her. In this case, the child has projected feelings of "being a loser" onto the therapist and managed to have her play the role of a critic.
492
This type of therapy is designed to address practical problems that children and adolescents face. It could be used to reduce conduct problems, ODD issues, drug use, or other issues that need more immediate help.
Brief strategic family therapy
493
What disorder is most commonly seen with body dysmorphic disorder?
MDD social phobia and OCD are often seen with BDD, but MDD is most common
494
Approx 65% of patients with GAD have a comorbid psychiatric disorder. What is the most common?
MDD
495
What percent of patients with OCD also have a comorbid anxiety disorder?
75%
496
What percent of patients with OCD also have a mood disorder?
60% (with MDD being the most common)
497
What percent of patients with OCD also have OCPD?
20-30%
498
At what age is the first comprehensive eye exam recommended?
6 months (between 6 months and 5 years) (infants can accommodate fully and visual acuity is nearly that of an adult.
499
What is the approx ratio of boys to girls in pediatric OCD?
3:2. Boys are approx 50% more likely to be dx'd with OCD than girls and are likely to be dx'd earlier.
500
age? 2 word sentences, 50 word vocab, follows 2 step commands, 50% intelligible
2
501
Age? three word sentences, says name and gender. 75% intelligible
3
502
Age? Names colors, understands adjectives, adult like grammar. 100% intelligible
4
503
Age? Counts, understands opposites, talks about past, present, and imaginary events. 100% intelligible
5
504
Medications approved for bipolar depression in youth?
Seroquel Er Latuda Olanzapine/fluoxetine
505
12M w schizophrenia, unusual looking face and has been noted to have episodes of hypocalcemia. He sees a cardiologist for hear defects. Which chr. was likely affected?
22q11.2 deletion syndrome //velocardiofacial syndrome // DiGeorge syndrome (CATCH 22) Cardiac abnormalities, abnl face, thymic aplasia, cleft palate, hypocalcemia, hypothyroidism
506
Patients with 22q11.2 deletion syndrome //velocardiofacial syndrome // DiGeorge syndrome have a ?x increased chance of developing schizophrenia.
20x
507
PTSD has been associated with alterations in the size of what?
hippocampus (reduced size). Although it is not clear if it is from the trauma or pre-dates the trauma
508
Children with behavioral inhibition are most likely to develop what disorder?
Social anxiety disorder.
509
What is one of the largest risk factors for developing social anxiety disorder?
Behavioral inhibition
510
Compared to adults, weight gain in kids from second generation antipsychotics typically...
is greater
511
Fully structured diagnostic instrument that assesses 34 common psychiatric diagnoses of children and adolescents. It cannot be used to establish a dx for conditions that require the interpretation of specialized test results or substitute for information derived from astute clinical observations. For these reasons, it does not cover diagnoses such as pervasive developmental disorders, speech and language disorders, or the organic brain syndromes.
Diagnostic Interview Schedule for Children (DISC)
512
Consider alt therapy with QTC is > ?
460 msec
513
The Individuals with Disabilities education Act (IDEA) gives what guidelines about the content of an IEP?
It gives guidelines about what topics must be addressed but does not guide the approach to writing it.
514
Mom doubled the DDAVP dose (for bed wetting). The kid has AMS, dizziness, and abdominal pain. What is he at risk for?
Water intoxication and hyponatremia. Can also present with vomiting and depressed reflexes, hallucinations and seizures
515
What case held that a parent or a guardian can commit a minor to a mental institution if a staff physician certifies the minor should be committed?
Parham v JR
516
A child is placed in restraints on the inpatient unit after becoming very aggressive. How often must vitals be monitored?
Q15 minutes
517
A child is undergoing therapy for self-injurious bx. The parents scolding the child when the self-injurious bx occurs and the undesirable bx decreases. In this scenario, scolding functions as which type of operant conditioning?
positive punishment (the addition of an undesirable stimulus to reduce a specific bx).
518
Removal of an undesirable stimulus to increase a specific bx
negative reinforcement
519
Removal of a desirable stimulus to decrease a specific bx
negative punishment
520
Addition of a desirable stimulus to increase a specific bx
Positive reinforcement
521
Punishment =
Reduce a specific bx
522
Reinforcement =
Increase a specific bx
523
During what stage of sleep do NMs occur?
REM (final 3rd of the night/early morning horus)
524
Sleep terrors occur during what stage of sleep?
non-REM (first 3rd of the night). The child is usually not responsive and does not generally remember the episode later.
525
Initial side effects of bupropion?
headaches, dizziness, dry mouth, anxiety, restlessness, anorexia, nausea, and insomnia
526
Patients with conduct disorder may exhibit polymorphism in what gene?
MAO-A
527
Patients with conduct disorder may exhibit what physiologic differences compared to the general population? (3)
1) lower resting heart rates 2) low skin conductance (electrical) 3) Increased testosterone
528
Damage to the ventrolateral preoptic nucleus (VLPO or VLPN) may cause what?
Disturbed sleep-wake cycles
529
Where is the ventrolateral preoptic nucleus (VLPO or VLPN) located?
Hypothalamus. Damage = disruption to sleep-wake cycle
530
TCA overdose - EKG shows?
QRS widening
531
Ingestion of grapefruit juice increases clomipramine concentrationthrough inhibition of CYP?
3A4
532
the half life of clomipramine is?
32 hours, but may increase at higher doses
533
Clomipramine is FDA-approved for the tx of what in kids 10+
OCD
534
Clomipramine is FDA-approved for the tx of OCD in what age group?
10 years +
535
Serious side effects of clomipramine include? (7)
Seizures, arrhythmia, syncope, QTC and QRS prolongation, sudden death, hematological issues (neutropenia, agranulocytosis, thrombocytopenia) and jaundice
536
A 14 month old child cries for 1 hour but is consoled when his mother picks him up from his crib. Which basic conflict describes this child?
trust v mistrust (birth to 18 months)
537
What medication is occasionally used with severe/nightly sleepwalking for a few months?
Benzos
538
At what age are most infants able to turn toward the sound of a voice?
3-4 months (hearing is the most sensitive of all senses at birth, depends on increasing neck strength)
539
When is homeostatic sleep drive at its lowest?
When a person wakes up in the morning. It increases throughout the day and lessens once a person is asleep. Circadian sleep drive then takes over for the second half of the night.
540
First degree relatives of a patient with ASPD have a ?x higher risk of being dx'd with ASPD.
5x
541
Prevalence of ASPD is about ?% in males and ?% in females?
3% in males and 1% in females
542
What percent of children with ADHD develop chronic tic disorder?
20%
543
What percent of kids dx'd with chronic tics or Tourette's syndrome have comorbid ADHD?
50%
544
Desmopressin (DDAVP) results in what 2 things re: urine?
Decreased urine outpt and increased urine osmolality
545
Desmopressin (DDAVP) - side effects?
headaches, nausea, flusing, and mild abd cramps
546
Desmopressin (DDAVP) increases factor ? and what else?
Factor VIII and plasominogen activator in the blood.
547
Desmopressin (DDAVP) - results in a ?% decrease in wet nights?
30-60%
548
Desmopressin (DDAVP) - oral dosing may be titrated as tolerated to how many mg at bedtime?
0.6 mg
549
16M involved in a MVA and sustained head trauma. He is now exhibiting a range of behavioral changes, and the psychiatrist is concerned about his executive functioning. What neuropsychological test would be most appropriate for his assessment?
Wisconsin Card-Sorting Test (incorrect = WISC measures intelligence and is often used when there is a discrepancy between a child's intelligence vs performance at school)
550
A child can jump but cannot yet balance on one foot. About 50% of the child's speech is understandable. The child can stack 6 blocks on top of each other. Age?
24 months
551
Gender identity usually begins to form by which age?
3
552
What term reflects the degree of control an individual exerts over the parts of bx that are driven by emotion?
Constraint
553
Kagan and colleagues have identified 2 distinct temperments in infants - what are they?
inhibited and uninhibited
554
What disorder most commonly occurs in patients with ASD?
Anxiety disorders and may have comorbid OCD.
555
When is social communication disorder dx'd?
If no restricted or repetitive bx patterns are present but other criteria for ASD are met.
556
What brain area has a smaller volume in patients with ADHD compared to controls?
Frontal lobe. In general, the total cerebral volume is smaller in individuals with ADHD than in controls.
557
The risk of major depression for 1st degree relatives of major depression probands who suffered an early age of onset and recurrent episode is more than ?x higher than the risk for relatives of probands who suffered a later onset, single episode.
5x
558
Individuals with panic disorder show increased sensitivity to the anxiogenic effects of substances like? (3)
1) carbon dioxide 2) cholecystokinin 3) lactate
559
What infection is linked to PANDAS?
group A beta-hemolytic streptococcal infections
560
Total sleep deprivation and REM sleep deprivation has been shown to lead to a substantial reduction of sxs in patients suffering from what?
Depression
561
By what age are most children able to hop on one foot?
4 years old
562
What are the most effective behavioral regiments for insomnia? (3)
1) stimulus control 2) sleep restriction 3) multi-component cognitive-behavioral interventions
563
What attributes of violent media when watched as a child can contribute to alter violence and aggression in young adulthood? (2)
1) How realistic the violence | 2) Identification with the aggressive character
564
If a young child does all of her chores for a week, she is rewarded with a weekly allowance of $10. What kind of operant conditioning schedule are her parents using?
Fixed interval. Provides reinforcement for a response that occurs after a set amount of time. The child is reinforced at a fixed weekly schedule as long as the bx occurs.
565
This type of schedule provides reinforcement every "n"th response.
Fixed ratio
566
This type of schedule provides reinforcement at a varying response rate.
Variable ratio
567
This type of schedule provides reinforcement for responses that occur after varying amts of time.
Variable interval
568
The visual acuity of a child reaches the adult level of 20/20 by what age?
3-5
569
Myelination of the optic nerves and the development of the visual cortex occur over what time period in kids?
Over the first two years
570
When does myelination begin?
Around 28 weeks gestation
571
Parietal and temporal lobes experience a growth spurt from what age range?
6-13. This growth spurt may correspond with a critical period of language development.
572
What technique is used in IPT to get a sense for what is going on?
An illness (depression) timeline reflecting major mood changes and significant interpersonal events.
573
MOA for PCP?
NMDA receptor antagonist.
574
PCP use in children - sxs?
Nystagmus, blank staring, strange bx, AMS, agitation, choreoathetosis, seizures, and acute psychosis
575
According to Piaget, conservation is achieved during what stage?
Concrete operational
576
According to Piaget, egocentrism and centering are part of what stage?
Preoperational
577
According to Piaget, logical and concrete reasoning occurs during what stage?
Concrete operational
578
According to Piaget, primary/secondary/tertiary circular reasoning occurs during what stage?
Sensorimotor
579
According to Piaget, primary circular reasoning occurs during the sensorimotor stage. What is this?
Primary Circular Reactions (1-4 months): This substage involves coordinating sensation and new schemas. For example, a child may suck his or her thumb by accident and then later intentionally repeat the action. These actions are repeated because the infant finds them pleasurable.
580
According to Piaget, secondary circular reasoning occurs during the sensorimotor stage. What is this?
Secondary Circular Reactions (4-8 months): During this substage, the child becomes more focused on the world and begins to intentionally repeat an action in order to trigger a response in the environment. For example, a child will purposefully pick up a toy in order to put it in his or her mouth.
581
According to Piaget, tertiary circular reasoning occurs during the sensorimotor stage. What is thi
Tertiary Circular Reactions (12-18 months): Children begin a period of trial-and-error experimentation during the fifth substage. For example, a child may try out different sounds or actions as a way of getting attention from a caregiver.
582
CY-BOCS age range?
6-17
583
CY-BOCS is based on three factors - what are they?
1) patient report 2) subjective report from parents 3) observation from clinician
584
The Brief Psychiatric Rating Scale (BPRS) is used to measure psychiatric sxs such as :
depression, anxiety, hallucinations, and unusual bx
585
At high doses trazodone works as a ?
Serotonin agonist
586
At low doses trazodone works as a ?
Serotonin antagonist
587
Trazodone: Oral absorption is ?% higher when taken with food.
20%
588
Trazodone may be arrhythmogenic - true or false?
TRUE
589
The onset of bipolar disorder prior to age 13 carries an especially poor prognosis. What percent of patients with bipolar disorder began to exhibit sxs at age 13 or earlier?
25-30%
590
What percent of individuals dx'd with bipolar disorder as adults had sxs prior to age 20?
60%
591
What percent of individuals dx'd with bipolar disorder as adults had sxs beginning between ages 13 and 18?
40%
592
A 504 plan specifies what but not what?
Specifies accommodations for disabilities but does not specific special education services.
593
In utero exposure to opiate does what to the incidence of SIDS?
It increases incidence of SIDS
594
Who is considered the founder of the strategic family therapy model?
Jay Haley
595
What is the process by which the expression of emotion by a group member stimulates the awareness of a similar emotion in another group member?
Contagion
596
The process of imparting a sense of optimism to group members
Inspiration
597
A study compares the incidence of SAs with BPD vs nl controls. The BPD group has 50 individuals and the control group has 500. The # of SA in the BPD group and the control group is 5. Calculation that determines the suicide risk attributable to BPD?
(5/50)-(5/500) = attributable risk = experimental event rate (events/subjects) = control event rate.
598
A study compares the incidence of SAs with BPD vs nl controls. The BPD group has 50 individuals and the control group has 500. The # of SA in the BPD group and the control group is 5. Calculation for relative risk?
(experimental event rate/control rate) = (5/50)/(5/500)
599
A study compares the incidence of SAs with BPD vs nl controls. The BPD group has 50 individuals and the control group has 500. The # of SA in the BPD group and the control group is 5. Calculation for odds ratio?
(5/45)/(5/495)
600
What is central to any reunification plan for children in foster care?
To support parents in resolving issues that lead to maltreatment and placement.
601
A psychiatrist is a consultant for her local elementary school. She is referred a patient from this school to see on an outpatient basis. Can she accept this patient?
Yes. As long as there is no active solicitation of these patients or other financial conflict of interest.
602
What are correctable causes of cognitive and behavioral disturbance?
Vision and hearing impairment, seizure disorders, recent head injury.
603
The solitary tract is critical for which part of sleep?
NREM sleep. The solitary tract projects ventrally through the basal forebrain to the cortex through the thalamus. It allows progressive hyperpolarization of the corticothalamic circuits during NREM sleep that underly the characteristic delta waves through which "deep sleep" is recognized.
604
What is meant by the term "goodness of fit" as described by Chess and Thomas?
match or mismatch between a person's temperament and features of his or her environment.
605
What are aspects of "goodness of fit"?
When the properties of the environment and its expectations and demands are in accord with the organism's own capacities, characteristics and style of behaving. Specific values, cultural differences, and SES must be taken into consideration.
606
3 classic FAS facial features?
1) smooth philtrum 2) thin vermilion border 3) palpebral fissures
607
Features of congenital rubella?
Sensorineural deafness, retinopathy, cataracts, congenital heart disease, microcephaly, micrognathia, and ID
608
Features of Down syndrome?
Upslanting palpebral fissures, epicanthic folds, folded or dysplastic ears, low-set small ears, and a flat nasal bridge
609
Features of congenital hypothyroidism?
lethargy, hoarse cry, feeding problems, myxedematous facies, macroglossia, umbilical hernia
610
Rhythmicity is a dimension of temperament - what does it refer to?
Indicates regularity of timing in the child's biological functions such as eating and sleeping
611
What is the third stage of Erik Erikson's therapy of psychosocial development?
Initiative vs. Guilt (age 3-5) Children begin to plan activities, make up games, and initiate activities with others. If given this opportunity, children develop a sense of initiative and feel secure in their ability to lead others and make decisions. Conversely, if this tendency is squelched, either through criticism or control, children develop a sense of guilt. The child will often overstep the mark in his forcefulness, and the danger is that the parents will tend to punish the child and restrict his initiatives too much.
612
Initiative vs. Guilt - age range?
3-5
613
Child is 75% understandable, can jump and hop a dn can stack around 8 blocks. Age?
36 months
614
Sxs of acute cocaine w/d?
Mild muscle pain and chills. There is a risk of MI d/t coronary vasospasm
615
How many hours after last drink does alcohol w/d start?
8-10 hours
616
Modafinil activates what area of the brain?
Hypothalamic regions
617
In clinical trials with children, modafinil has proven efficacy in reducing sxs of ADHD. Why did it not get FDA-approval for use in children?
Risk of SJS
618
What are the phenotypic attributes of fetal VPA?
1) epicanthic fold 2) infraorbital groove 3) medial deficiency of eyebrows 4) flat nasal bridge 5) broad nasal root 6) anteverterd nares 7) shallow philitrum 8) long upper lip 9) thick lower lip 10) small downturned mouth
619
Non-episodic irritability in youth has not been shown to increase the risk of bipolar disorder. It carries an associated risk for what disorders?
Anxiety and unipolar depressive disorders
620
MDD has a heritability of what percent?
40-60%
621
AN occur in females what percent of the time?
> 90%
622
The lifetime prevalence of AN in females is ?
0.5%
623
The long-term mortality rate of AN?
>10%
624
The lifetime prevalence of BN in females is ?
1-3%
625
BN occur in females what percent of the time?
90%
626
Duration of an untreated episode of MDD?
4+ months
627
A father presents with his 6 y/o daughter and asks about bringing her to the funeral of a 9 y/o sibling who died suddenly in a car accident. What factor is most relevant for advising the family?
Availability of supportive adults to provide comfort Generally, attendance can be helpful