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CAPA ABX Flashcards

1
Q

PenG admin

A

IV or IM

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2
Q

Pen VK admin

A

PO

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3
Q

Benzthine penicillin admin

A

long acting IM (syphillus)

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4
Q

Common treatments for natural penicillinss

A

strep pharngitis, cellulitis

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5
Q

Aminopenicillins (2 examples)

A

ampicillin, amoxicillin

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6
Q

Ampicillin admin

A

IV

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7
Q

Common treatment for aminopenicillins

A

pharyngitits, sinusitis, otitis media, endocarditis prophalaxsis, lyme dz (for patients under 8)

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8
Q

Antistaph penicillins do/do not have MRSA coverage

A

DO NOT

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9
Q

Antistaph penicillins examples (2)

A

nafcillin (IV), dicloxacillin

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10
Q

Antistaph penicillins treatments

A

skin and soft tissue with suspected staph, but works well against strep as well

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11
Q

Augmented penicillins examples

A

augmentin, ampicllin/sulbactam (unasyn) (IV)

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12
Q

Coverage of aminopenicillins

A

streps, enterococci, boriellia bordorfi, listeria

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13
Q

Coverage of augmented penicillins

A

streps, enterococci, bergdorfi, lsiteria+ pastuerlla, morxella, Hflu, anaerobes**

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14
Q

treatment for augmented aminopencillins

A

dog bites, human bites, otitist media, sinusistis, acute exacerbation of chronic bronch, dental infections, skin and soft tissue

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15
Q

Augmented extended spectrum example…and added covereage

A

piptazo, all the above + PSEUDOMONAS

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16
Q

MOA of penicillins

A

stops cell wall syntesis by binding penicillin binding protein

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17
Q

Penicillin MOR

A

lactamases and PBP alteration

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18
Q

Peniciliins are ________ processed

A

renally

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19
Q

Clavulanate is associated with __________(adr)

A

diarrhea

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20
Q

Ceaphalosporins (1 gen) has great ___________ but poor _________ coverage

A

gram + (EXCEPT MRSA), gram-

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21
Q

examples of 1st gen cephalosporins

A

cefazolin (ancef IV) or cephalexin (Keflex PO)

22
Q

What doesn’t 1st gen cephalosporin cover?

23
Q

Common treatment indiciations for 1st gen cephalosporins

A

skin and soft tissue, strep pharyngitis, preof prophalzais (cefazolin), uncomplicated cyctisit

24
Q

2nd gen cephalosporins examples

A

cefuroxime (ceftin)

25
2nd gen coverage
covers same as 1st, +strep pneumo, mcat, hflu
26
1st gen ceph coverage
strep pyogenes, MSSA, some gram - E coli, klebsiella, proteus
27
2nd generation cephalosporins exampel
cefuroxime (ceftin PO)
28
3rd generation cephalosporins examples
Ceftriazone (IV IM), cefdini (omnicef PO)
29
3rd gen ceph coverage
gram - with some gram +, NOT enteroccosu or MRSA
30
4th gen name and coverage
cefepime (IV) most gram - rods, +PSEUDOMONAS***
31
Next gen cephalosporins name and coverage
very broad gram - and gram + coverage, MRSA coverage****
32
penem general coverage
broad, excellent gram -, includes pseudomonas** (except ertapenem)
33
Carbapenems are usually used for __________
more resistant bacteria such as ESBL and pseudomonas
34
ADRs for carbapenems
seizures (especially imipnenm) and nephrotoxicity
35
Tetracyclines does or do not cover MRSA
do
36
MOA of tetercyclines
protein synthesis inhibition at 30S bacterial ribosome
37
MOR of tetracyclines
efflux pump
38
ADRs for tetracyclines
photosensitivity, contrainidicated in pregnancy
39
examples of tetracyclines
mino, tetra, doxy
40
Macrolides examples
ACE, Azitrho (PO or IV), claritho (PO), erythromycin (PO or IV)
41
Macrolide coverage
strep pneumo, strep pyogenes, mcat,, Hflu, ***chlamydia, mycoplasm, hpylori, bordetella pertusis
42
MOA of macrolides
protein synthesis inhibition at 50S ribosome
43
MOR of macrolides ribosolmal changes and efflux pump
kj
44
Safety concerns with macrolides
Clrithro is a CYPA4 inhibitor, monitor warfarin. QT prolonations (azithro)
45
ADR to erythromycin
nausea/vomiting/diarrhea
46
Special treatment for macrolides
whooping cough****
47
Lincosamides examples
clindamycin (PO, IV)
48
Coverage of lincosamides
anaerobes above diaphragm, Staph/strep in PCN allergic patient
49
MOA of lincosamides
protein synt inhibition at the 50S ribosome
50
MOR of lincosamides
ribosomal modications
51
ADRS of lincosamides
Nause/ diarrhea, CDIFF

ross hypothermia (2 decks)

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