carbapenems Flashcards
1
Q
what are the broadest spectrum of B-lactams?
A
carbapenems
2
Q
combining what drug with cilastatin is used to treat UTI’s?
A
imipenem
3
Q
Cilastatin inhibits what?
A
dehydropeptidase
4
Q
what does dehydropeptidase do?
A
breaks down imipenem very quickly
5
Q
what are the side effects of imipenem?
A
nausea and vomiting, increased risk of C difficile infection, and seizures
6
Q
which carbapenem results in fewer seizure occurrences than imipenem?
A
meropenem
7
Q
Rx interaction: carbapenems can decrease levels of _____ and thus _____ risk of seizures
A
valproic acid, increase
8
Q
which carbapenem has one day dosing?
A
ertapenem
9
Q
which carbapenem is not used for pneumonia due to increased risk of death?
A
doripenem
