Carbohydrate metabolism Flashcards

1
Q

Digestions is generally completed by the time the stomach contents reach the

A

Junction of the duodenum and jejunum

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2
Q

In the mouth, dietary carbohydrates are first acted upon briefly by the first enzyme ___

A

Salivary amylase (Ptylain)

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3
Q

Salivary amylase hydrolyze___ bonds

A

alpha 1,4 glycosidic bonds

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4
Q

Cellulose contains __ bonds

A

beta 1,4 glycosidic bonds

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5
Q

In the stomach, CHO digestion is stopped temporarily by the

A

Low pH of the gastric juice which inactivates salivary amylase

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6
Q

In the small intestines, further CHo digestion is brought about by

A

Pancreatic a-amylase

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7
Q

Final digestion occurs in the ___

A

mucosal lining of the upper jejunum

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8
Q

Digestive fluid that acts in the upper jejunum

A

Succus entericus

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9
Q

Hydrolyzes alpha 1,6 glycosidic bonds to form glucose from oligosaccharides and isomaltose

A

Isomaltase

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10
Q

Absorption of carbohydrates occurs only in the ___

A

Small intenstines (duodenum and upper jejunum)

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11
Q

Mechanism for absorption of glucose and galactose

A

Active transport, needs energy and a carrier protein molecule, and a co-transport system with Na+

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12
Q

Mechanism for absorption of fructose and mannose

A

Facilitated diffusion (rapid)

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13
Q

Mechanism for absorption pentoses like riboses

A

Simple diffusion through the lipid bilayer

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14
Q

Fructose specifically uses ___ as it moves from the luminal side towards the inside of the cell and into the serosal side

A

GLUT 5 (facilitative glucose transporter)

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15
Q

Tissue distribution of GLUT 1

A
Human RBC
BBB
BRB
BPB
BTB
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16
Q

Tissue distribution of GLUT 2

A

Liver
Kidney
Pancreatic B cell
Serosal surface of intestinal mucosal cells

17
Q

Tissue distribution of GLUT 3

A

Brain

CNS

18
Q

Tissue distribution of GLUT 4

A

Adipose tissue
Skeletal muscle
Heart muscle

19
Q

Tissue distribution of GLUT 5 fructose

A

Intestinal epithelium

Spermatozoa

20
Q

Humans lack this enzyme which breaks down cellulose

A

Beta 1,4 glucosidase

21
Q

Lactase deficiency leads to

A

Lactose intolerance

22
Q

Metabolic hub

A

liver