Carbohydrates Flashcards

1
Q

Which of the following autoantibody assay is commonly detected with an adult-onset Type 1 Diabetes mellitus?
a. GAD65
b. Zinc transporter 8
c. IAA
d. Insulinoma-associated protein 2

A

a. GAD65

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2
Q

Which of the following conditions is associated with a high insulin and low C-peptide level?
a. Insulinoma
b. Diabetes mellitus
c. Congenital hyperinsulinism
d. Hypoglycemia from exogenous insulin

A

d. Hypoglycemia from exogenous insulin

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3
Q

Which of the following is associated with an abnormal glucose homeostasis but glucose level is not high enough to classify as diabetes?
a. Cystic fibrosis
b. Pre-diabetes
c. Insulin deficiency
d. Glucagonoma

A

b. Pre-diabetes

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4
Q

Which of the following is the most common disorder of carbohydrate metabolism?
a. Von Gierke disease
b. Hypoglycemia
c. Glycogen storage disease
d. Diabetes

A

d. Diabetes

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5
Q

Which of the following best characterizes amylin?
a. Lowers post prandial hyperglycemia
b. Stimulate glucose production
c. Stimulates appetite
d. Stimulates glucose uptake and the formation of
glycogen

A

a. Lowers post prandial hyperglycemia

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6
Q

What is the most common cause of non-iatrogenic hypoglycemia in ages 18 months to 5 years old?
a. Hers disease
b. Ketogenic hypoglycemia
c. Insulinoma
d. ongenital hyperinsulinism

A

b. Ketogenic hypoglycemia

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7
Q

A 56-year-old male suddenly complained of palpitation, tremulousness, anxiety and frequent hunger. The patient was on maintenance medication for hypertension and was recently shifted to Carvedilol. Laboratory work-up was done and only revealed hypoglycemia. The attending
physician suspected Carvedilol as the cause of hypoglycemia. Which of the following explains the cause of hypoglycemia due to the patient’s present medication?
a. Increases insulin and C-peptide
b. Blocks Kir6.2 subunit of the pancreatic beta cell
c. Inhibits hepatic gluconeogenesis
d. Antagonizes catecholamine-mediated
glycogenolysis

A

d. Antagonizes catecholamine-mediated
glycogenolysis

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8
Q

An 11-month-old baby boy was brought to the OPD for consult. The parents noticed that the baby started to have cloudiness of both eyes and they also noticed that the he had limp extremities. The baby does not respond to any sounds and still cannot babble vocally. Which of the following best explains the condition of the patient?
a. GALE deficiency
b. GAKT deficiency
c. GALT deficiency
d. GALK deficiency

A

a. GALE deficiency

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9
Q

Which of the following is responsible in converting proinsulin to insulin?
a. C-peptide
b. Phosphorylase kinase
c. Glycogen synthase
d. Beta-hydroxybutyrate

A

a. C-peptide

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10
Q

When is the best time to draw blood for testing in drug-induced hypoglycemia?
a. After 8 hours fasting
b. Hypoglycemic episode
c. 2 hours post prandial
d. Anytime

A

b. Hypoglycemic episode

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