Cardiac Flashcards

(77 cards)

1
Q

Primary cause of death and disability in the US

A
  1. CHA (coronary heart disease)
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2
Q

1 out of every (?) deaths are caused by CHD

A

5

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3
Q

based on the slides what has is the most valuable modifiable risk factor

A

diet

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4
Q

Essential substance required for synthesis of:
Cell membranes
Steroid hormones
Multiple other compounds utilized in daily physiological processes

A

cholesterol

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5
Q

Transport cholesterol and triglycerides

A

Lipid proteins

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6
Q

Transport dietary exogenous triglycerides (TG) and cholesterol from the

intestines to the liver

A

Chylomicrons

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7
Q

Transport endogenous cholesterol from the tissues to the liver

A

HDL

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8
Q

Transport TG & cholesterol from liver into circulation

A

VLDL

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9
Q

Transport TG & cholesterol within circulation

A

LDL

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10
Q

total cholesterol

A

TC: HDL+LDL+VDL

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11
Q

Good cholesterol

A

HDL

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12
Q

TG are elevated when

A

non fasting state

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13
Q

when fasting what cant you have

A

coffee

cum

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14
Q

when fasting can you have water

A

yes

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15
Q

V-LDL carries what

A

primarily TG

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16
Q

what is the good Apolipoprotein

A

A-1

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17
Q

Responsible for reverse cholesterol transport

A

HDL

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18
Q

Fatty material and plaque are deposited in the wall of an artery

A

Atherogenesis

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19
Q

what is the initial stage of Atherogenesis

A

vesicle inflammation

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20
Q

most TG are found in what lipid protein

A

V-LDL

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21
Q

how to calculate V- LDL

A

TG/5

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22
Q

Friedewald equation

A

Total cholesterol= HDL+LDL+ VLDL

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23
Q

normal Total cholesterol

A

< 200 mg/dl

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24
Q

Normal HDL

A

> 40 mg/ dl

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25
Normal V-LDL
<30 mg/ dl
26
Normal LDL
< 130 mg/dl
27
Normal TG levels
< 150 mg/dl
28
3 issues on EKG that would indicate an oh shit
1. T wave inversion 2. ST elevation 3. Abnormal Q wave
29
T wave inversion indicates what
ischemia
30
ST elevation indicates
acute MI
31
Abnormal Q wave indicates what
tissue death
32
CK or CPK stands for what
Creatine Kinase
33
Creatine Kinase is located where
94% CK-MM: muscle 6% CK-MB: Heart 0% CK-BB: Brain These percentages are what you should find in the brain
34
Creatine Kinase hour by hour
Rise 4-6 hours , peak 18-24 hours, normalizes 48-72 hours
35
How is the sensitivity of CKMB for acute MI
Dog shit sn: 52%
36
with cardiac biomarkes MB stands for what
myoglobin
37
MB hour by hour
Rise in 2-4, peak 6-12, normalize 24-36
38
SN and SP for MB
Sensitivity of 83% and specificity of 99%
39
most SN cardiobiomarcker for acute MI
troponin I (sn99%)
40
timeline hour by hour for troponin C
Increases within 2-6, peak 18-24 hours, hours and normalizes in 7-14 days
41
Cut off values for troponin I
.04 MI
42
Most specific test for MI
MB
43
Secreted primarily by the ventricular myocardium in response to wall stress Ventricular volume expansion Pressure overload
BNP
44
BNP value for CHF
>400pg/ml
45
High Sensitivity C-Reactive Protein tests for what
inflammatory disorders
46
A prothrombin time tests what
clotting time
47
INR is associated with what
clotting time
48
Injury to a vein or artery activates the coagulation cascade, creating a blood clot.
D dimer (SP but not SN)
49
Biggest contribute to cardiovascular disease
coronary heart disease
50
Biggest modifiable risk factor to coronary heart disease
poor diet
51
what race has the highest cholesterol
mexican
52
Transport cholesterol and triglycerides
Lipid proteins
53
Cell membranes Steroid hormones Multiple other compounds utilized in daily physiological processes
cholesterol
54
Transport dietary exogenous triglycerides (TG) and cholesterol from the intestines to the liver
Chylomicrons
55
Chylomicrons and VLDL have greatest concentration of what
TG's
56
How long do you have to fast for a TG test
8-10 hours
57
Pre-cursor of IDL and LDL
V-LDL
58
Contains Apolipoprotein B
VLDL
59
Densest and smallest of lipoproteins | Contains Apolipoprotein A-1
HDL
60
Atherosclerosis starts in what decade of life
1st
61
The Friedewald equation should not be used under the following circumstances:
When chylomicrons are present which means that the patient should be fasting for 8 to 10 hours When plasma triglyceride concentration exceeds 400 mg/dL
62
C reative protein has to do with what
vascular injury
63
PT is a coagulation test that measures the time it takes to form a firm fibrin clot after thromboplastin (factor III) and calcium are added to the serum sample.
PT/ INR | prothrombin time
64
who clots faster children or adults
children
65
Injury to a vein or artery activates the coagulation cascade, creating a blood clot.
D dimer
66
D dimer is highly ...
sensitive
67
How long do halter monitors record
1-2 days
68
How long do event reorders monitor
2-30 days
69
until what % do you do a cardiac stress test
85%
70
Dobutamine | Adenosine
chemical stress test
71
Detection and recording of timing and conduction of electrical impulses Induce arrhythmias and see where they originate
EPS
72
what do you not want on a dopler vein
red- This means it;s moving fast
73
what test looks at the structure of teh heart
echo
74
Transesophageal Echocardiography
looks at posterior heart
75
what is the best test for vesicle
CT
76
best for valves and coronary arteries
cardiac catheterization
77
Measures pressure in the RA and RV pulmonary artery
Swan Ganz catheter