Cardiac Flashcards

(49 cards)

1
Q

Primary Prevention

A

QRISK 3 Score - percentage risk of stroke or MI in 10years.
>10% = start a statin - atorvastatin 20mg night
Also CKD and diabetes T1 patient = atorvastatin 20mg
Aim for > 40% reduction in non-HDL cholesterol. Check at months.
SE statin- can cause rise in ALT, AST in first few weeks so LFTs check in 3months. (<3x rise from normal)
Myopathy - check creatine kinase if muscle pain

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2
Q

Secondary prevention

A

4 A’s
Aspirin + second antiplatelet - clopidogrel.
Atorvastatin 80mg
Atenolol (betablocker) or bisoprolol to max tolerated dose
ACE inhibitor - Ramipril to max titrated dose

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3
Q

PCI

A

Percutaneous Coronary Intervention
Angioplasty- dilating the blood vessel with ballon or stent.
Proximal or extensive disease on CTa

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4
Q

CABG

A

Coronary artery bypass graft
Severe stenosis
Open surgery - along sternum (midline sternotomy) graft vein from leg - graft saphenous vein. Bypass stenosis. Higher complication rate to PCI, longer recovery.
ISCES- check for fem/brach / chest scars.

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5
Q

Angina

A

Stable - Sx relived by rest or GTN
Unstable- type of ACS
Pain can radiate to jaw or arms. Constricting

Investigations: CT Coronary angiogram = gold standard 
Phy exam- BMI, Hr Sounds, signs Hr failure
ECG
FBC (anaemia )
LFT’s (prior to statin)
U&Es (prior to ACEI)
Lipid profile 
Thyroid tests
HbA1C and fasting glucose.
Management: RAMP
Refer to cardiology 
Advise
Medical Tx
Procedural or surgical interventions 

GTN - immediate relief, 5min x2
Beta blocker- bisoprolol 5mg OD
Calcium channel blocker - amlodipine 5mg OD
Long acting nitrates - isosorbide mononitrate

Prevention: AAAA
Aspirin 75mg OD
Atorvastatin 80mg OD
Ace I
Already on BB
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6
Q

Acute coronary Syndrome

A
Thrombus from AS Plaque - made up mostly of platelets (fast flowing artery)
3 types: 
Unstable Angina
ST elevation MI - STEMI
NSTEMI 

Diagnosis:
ECG - if elevation/ new LBBB = STEMI
Troponin ^ or other ECG changes (depression, t wave inversion, Path Q waves )= NSTEMI
Non= unstable angina or MSK chest pain.

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7
Q

ACS Sx

A
Central constricting Chet pain associated with:
Nausea and vomiting
Sweating and clamminess 
Feeling of impending doom 
SoB
Palpitations
Pain radiating to jaw or arms 

Sx should continue at rest for >20mins. Diabetics - silent MI

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8
Q

Troponin levels

A

Elevate within 3-4 hours after damage, remain high for 14days.
Other causes ^ trop = myocarditis, PE, drug abuse, vasculitis, sepsis, renal failure, aortic dissection .

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9
Q

Acute STEMI Tx

A

Within 2hr = PCI

If PCI not available within 2hr = thrombolysis - fibrinolytic - streptokinase, alteplase, tenecteplase.

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10
Q

Acute NSTEMI Tx

A
BATMAN
Beta blocker
Aspirin 300mg stat
Ticagrelor 180mg stat (or clopidogrel 300mg)
Morphine 
Anticoagulant LMWH - Enoxaparin 1mg/kg BD 2-8days
Nitrates - GTN to relieve spasm 
O2 only if stats below 95%

GRACE score - PCI in NSTEMI
6month risk of death or repeat MI <5%, 5-10%, >10%
Med, high risk considered for early PCI within 4 days.

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11
Q

Cor Pulmonale

A

Right Sided heart failure - resp disease
Back pressure into vent, atrium, VC and systemic venous system.
Causes: COPD, PE, Interstitial lung disease, CF, 1 Pulmonary HT
Pres: Often asymptomatic, SoB, Peripheral oedema, syncope, chest pain.
Signs: hypoxia, cyanosis, raised JVP, Edema, third heart sound, murmur ( pan-systolic in tricuspid regurgitate ), hepatomegaly.
Man: LT O2 therapy often, Tx cause.

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12
Q

Causes AF

A
SHIMMERS
Soaring BP, hypertension 
Heart failure
Ischemic heart disease
Myocardial infarction 
Mitral value disease 
Ethanol / endocrine Eg thyrotoxicosis 
Resp causes; pneumonia, PE , bronchial carcinoma, rheumatic heart disease 
Sick sinus syndrome/ Sepsis
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13
Q

Medical cardioversion

If heamodynamically stable

A

IV flecanide or amiodarone if evidence of structural heart disease
Within 48hrs and stable

Plus rate control - bisoprolol

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14
Q

IV adenosine

A

Atrial flutter
PVST: paroxysmal supraventrical tachy
Wolff Parkinson white syndrome

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15
Q

Natural rate of heart parts

A

SA node: 60-100
AV node: 40-55
Bundle of his: 25-40
Bundle branches: 25-40

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16
Q

2 weeks post MI
Fever
Pleuritic chest pain
Pericardial rub on auscultation

A

Dressler’s syndrome
Local immune response causing pericarditis / pericardial effusion
Rarely a tamponade
Diagnosis: ECG- global ST elevation and T wave inversion
Echo
Raised CRP, ESR
Management: NSAIDs , severe cases steroids (prednisolone)
May need pericardiocentesis to remove fluid

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17
Q

Secondary prevention of MI medical management 6 As

A

Aspirin 75mg daily
Another anti platelet : clopidogrel for up to 12months
Atorvastatin 80mg
Ace inhibitor Ramipril
Atenolol
Aldosterone antagonist - those in clinical HF , eplerenone

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18
Q

SVT

A

Narrow QRS complex because rapid excitation of ventricles

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19
Q

VT

A

From ectopic focus
Wide QRS, 120-200 bpm
1. Monomorphic- classically myocardial scarring due to MI
2. Polymorphic - ischemia, not associated with scarring, different areas of V, brugada syndrome (autosomal dominate, Asian, st elevation, pseudo RBBB)
Tornadoes de pointes (k channels effected, prolonged QT interval)- Tx MgSO4

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20
Q

QT prolongation drugs

A
Anti arrhythmics 
B antibiotics macrolides 
C antipsychotics - olanzepine, haloperidol 
D antidepressants - TCA 
E antiemetics   - ondansetron
21
Q

Shockable rhythms

A

Ventricular tachycardia
Ventricular fibrillation
SVT- shock to cardioversion if other Tx fail

22
Q

Non shockable rhythms

A

Pulseless activity

Asystole

23
Q

External cause of 3rd degree heart block

A

Lyme disease
Meds: b blockers, amiodarone, digoxin, calcium channel blockers, adenosine
Neonatal lupus- congenital heart block
Av block may be normal in athletes

24
Q

Rbbb

A
Wide QRS 
V123 RSR configuration - right side 
MaRRoW
Causes: R ventricular hypertrophy, R HF, pulmonary embolism 
Can be normal
25
Lbbb
``` Qrs wide Lead V5,6 , aVL, 1 Broad S wave in V1 WiLLoW Causes: never in normal hearts Hypertension Ischemia Dilated cardiomyopathy Aortic stenosis May be sign of MI ```
26
SVT
Within AV node Alcohol and coffee Absence of normal p waves 150-250 bpm Collapses for a few seconds Tx : Vagal manoeuvre-carotid sinus stimulated - Vargas nerve - slows HR Adenosine -15seconds , indending dome,
27
Sinus bradycardia
Hypothyroidism Inferior MI Anorexia Cushing reflex - (Brady, hypertension, irregular resp pattern), from increased ICpressure, May indicate brain herniation so emergency Meds: b blockers, opioids, calcium blockers Tx: IV atropine
28
Reentrant arrhythmias
PSVT Atrial flutter AF
29
Atrial flutter
250-350bpm Usually 2:1 av conduction Around tricuspid value
30
Holiday heart syndrome
VF after binge drinking
31
Wolff Parkinson white syndrome
Preexcitation syndrome - can lead to SV arrhythmias, PSVT Bundle of Kent between atria and ventricle ECG: shortening of PR interval, widening of QRS, presence of delta wave (upward slurring of QRS complex) Delta wave indicates V activation earlier than it should be Mostly Asx
32
Commonest cause of viral myocarditis
Coxsackie B virus
33
Slurred upstroke of QRS
Delta wave | Wolff Parkinson white syndrome
34
Splinter haemorrhages Osler nodes Jane way lesions
Infective endocarditis
35
MI management
``` High flow O2 Aspirin and clopidogrel GTN spray Morphine B blocker ```
36
SVTtreatment
Carotid sinus massage and vagal manoeuvres Cardioversion Adenosine Catheter ablastion
37
Systolic murmur heard loudest on back below left scapula. | Infancy
Coarctation or aorta. - Narrowing Sx: difficulty breathing, pale, sweating, irritable or asymptomatic Signs: high BP, headaches, nosebleeds, muscle weakness, cramps, chest pain. BP difference in arms vs legs Murmur Weak or delayed pulse in legs
38
Systolic murmur best heard upper left sternal edge radiating to left shoulder / back Loudest during inspiration
Pulmonary stenosis During inspiration increases preload Quiet in valsalva because decreased preload.
39
Ejection systolic murmur best heard over second intercostal space RHS Radiated to carotid arteries Quiet second heart sound
Aortic stenosis | Murmur softens with standing or valsalva manoeuvre
40
Hypertrophic obstructive cardiomyopathy
HOCM syncope Ejection systolic murmur loudest between apex and left sternal border Can radiate to super-sternal notch but NOT carotids. Murmur typically louder with decrease in preload such as valsalva manoeuvre and standing.
41
ECG changes stay for how long after MI STEMI Days: Weeks/ months : Years:
ST elevation t waves Q Waves
42
Chronotrophic drugs | Effect HR
Beta blockers Some calcium antagonists - verapamil diltiazem Digoxin Ivabradine
43
Low amp oscillations Irregular irregular Absence of P waves Ventricular rate often 100-80
A fib
44
CHA2DS2VASc
Atrial fib stroke risk scoring system - congestive heart failure - hypertension - age >75 - diabetes mellitus - stroke / TIA / thromboembolism - vascular disease ( previous MI, peripheral artery disease) - age 75-74 - sex - female
45
HAS BLED
Major bleeding risk Hypertension Abnormal liver / renal function Stroke history Bleeding tendency / predisposition Labile INR Elderly >65 Drugs (aspirin, NSAIDs , alcohol)
46
Cardiac tamponade triad
Becks triad : Distant heart sounds Distended Jugular veins Decreased arterial pressure Tx : pericardiocentesis - needle under ultrasound
47
25yo male with syncope following palpitations ECG shows Delta waves in V1 No other med Hx generally fit and well.
Wolf Parkinson white syndrome Accessory pathway - fast atrial rhythm Can lead to SVT - syncope
48
Cardioversion for VT | Stable vs unstable
Stable - chemical - amiodarone or lidocaine | Unstable - electrical DC cardioversion (pulseless/ hypotensive)
49
Types of stroke
1. Ischemic 85% - atherosclerosis, afib, small vessel D 2. Haemorrhagic 15% - intracerebral, subarac, aneurysm, anticoagulant meds 3. TIA ``` Tx: thrombolytics within 4.5hours alterplase Thrombectomy Aspirin Clopidogrel Anticoagulant: warfarin, or apixiban ```